Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jihua Guan"'
Publikováno v:
CyTA - Journal of Food, Vol 21, Iss 1, Pp 171-180 (2023)
ABSTRACTCamellia oleifera（C. oleifera）is one of the four main woody oils of the world. Research on improving the productivity of C. oleifera has focused on the growth process, with much less research on the mechanism of lipid accumulation post-ri
Externí odkaz:
https://doaj.org/article/b7caf9ab0ac44933a1678f668b63cadc
Autor:
Jianwen WU, Xing FAN, Xiangying HUANG, Guiqing LI, Jihua GUAN, Xingyue TANG, Mi QIU, Suhua YANG, Shunzhong LU
Publikováno v:
South African Journal of Chemical Engineering, Vol 35, Iss , Pp 8-13 (2021)
The traditional drying method of Camellia oleifera seeds is sun drying and shade drying. In order to further improve the oil content and production efficiency, light and no light treatment were carried out and the oil quality was compared. The result
Externí odkaz:
https://doaj.org/article/b93302215ed940adb7e2946217cdda44
Autor:
Zhihua Sui, George F. Allan, James C. Lanter, Olivia Linton, Raymond A. Ng, Tifanie Sbriscia, Scott G. Lundeen, Vernon C. Alford, Jihua Guan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:784-788
The synthesis and in vivo SAR of 5,6-dichloro-benzimidazole derivatives as novel selective androgen receptor antagonists are described. During screening of 2-alkyl benzimidazoles, it was found that a trifluoromethyl group greatly enhances antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c946c8236b59026fcce73b3babce7dbe
https://doi.org/10.1016/j.bmcl.2006.10.071
https://doi.org/10.1016/j.bmcl.2006.10.071
Autor:
George F. Allan, Peifang Zhu, Joseph W. Gunnet, Olivia Linton, Nareshkumar F. Jain, Keith T. Demarest, Scott G. Lundeen, Jihua Guan, Pamela Tannenbaum, Xin Chen, Fu-An Kang, Jun Xu, Zhihua Sui
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:907-910
A novel series of oxa-steroids 6 derived from (8S, 13S, 14R)-7-oxa-estra-4,9-diene-3,17-dione 1 have been synthesized and identified as potent and selective progesterone receptor antagonists. These novel oxa-steroids showed similar potency to mifepri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1159f96481f08897c9d24f53de4a2ce7
https://doi.org/10.1016/j.bmcl.2006.11.062
https://doi.org/10.1016/j.bmcl.2006.11.062
Autor:
Joanna Clancy, Weiqin Jiang, Elizabeth Craig, Donna Haynes-Johnson, T. Mathew John, Patricia Kraft, Zhihua Sui, Mark J. Macielag, Sheela Bhattacharjee, Jihua Guan, Scott G. Lundeen, Yuhong Qiu
Publikováno v:
European Journal of Pharmacology. 472:73-80
We have characterized a novel, potent, and selective phosphodiesterase type 5 inhibitor, JNJ-10258859 ((R)-(−)-3-(2,3-dihydro-benzofuran-5-yl)-2-[5-(4-methoxy-phenyl)-pyrimidin-2-yl]-1,2,3,4-tetrahydro-pyrrolo[3,4-b]quinolin-9-one). Its inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791017e04b27dcb9f66397eb46dc9f1c
https://doi.org/10.1016/s0014-2999(03)01868-5
https://doi.org/10.1016/s0014-2999(03)01868-5
Autor:
Weiqin Jiang, Yuhong Qiu, Zhihua Sui, Patricia Kraft, Mark J. Macielag, T. Matthew John, Elizabeth Craig, Joanna Clancy, Sheela Bhattacharjee, Jihua Guan, Donna Haynes-Johnson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:761-765
A series of N(2)-furoyl and N(2)pyrimidinyl beta-carbolines was discovered to possess potent inhibitory activity against PDE5. During the synthesis we developed a tandem resin quenching protocol, which allowed us to synthesize large number of target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2413d565e29bc564da6c797b2216b0e4
https://doi.org/10.1016/s0960-894x(02)01036-3
https://doi.org/10.1016/s0960-894x(02)01036-3
Autor:
Michael Loeloff, Glenda C. Webb, Jihua Guan, Zhihua Sui, John F. Barrett, Mark J. Macielag, Raul Goldschmidt, Barbara D. Foleno, Dennis J. Hlasta
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:1929-1934
A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/SpoOF and NRII/NRI. They also showed inhibitory activity in whole cell mechanism-based assays, and they possessed pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c7572a1abb6146db6f2c11179fce2f
https://doi.org/10.1016/s0960-894x(98)00325-4
https://doi.org/10.1016/s0960-894x(98)00325-4
Autor:
Yuhong Qiu, Joanna Clancy, Suying Zhang, Patricia Kraft, Sheela Bhattacharjee, Mark J. Macielag, Zhihua Sui, T. Matthew John, Donna Haynes-Johnson, Weiqin Jiang, Jihua Guan
Publikováno v:
Journal of Medicinal Chemistry. 45:4094-4096
A series of N-pyrimidinylpyrroloquinolones were discovered as extremely potent and selective PDE5 inhibitors. Representative compounds demonstrated in vivo efficacy in dog erectile dysfunction models and are orally bioavailable.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46df627fe3c6d42a6f7bfed4928f2f4b
https://doi.org/10.1021/jm025545d
https://doi.org/10.1021/jm025545d
Autor:
Glenda C. Webb, Michael Loeloff, Dennis J. Hlasta, Raul Goldschmidt, Jihua Guan, Barbara D. Foleno, Mark J. Macielag, Zhihua Sui, John F. Barrett
Publikováno v:
ChemInform. 29
A series of diaryltriazole analogs was discovered to inhibit bacterial two-component regulatory systems in our primary assays, KinA/SpoOF and NRII/NRI. They also showed inhibitory activity in whole cell mechanism-based assays, and they possessed pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc286cf06ffd0f3a44459f6199a68f49
https://doi.org/10.1002/chin.199847288
https://doi.org/10.1002/chin.199847288
Autor:
Monica Singer, Michael Paul Ferro, Michele Steber, Dennis C. Argentieri, Michael P. Wachter, Kathy McCoy, William V. Murray, Dave M. Ritchie, Jihua Guan, Zhihua Sui
Publikováno v:
ChemInform. 31
Novel 1,3-diarylcycloalkanopyrazoles 1, and diphenyl hydrazides 2 were identified as selective inhibitors of cyclooxygenase-2. The 1,3-diaryl substitution pattern of the pyrazole ring in 1 differentiates these compounds from most of the known selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6d7793e802874d9a7f8749a9d2315b1
https://doi.org/10.1002/chin.200028121
https://doi.org/10.1002/chin.200028121