Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Jiho Jang"'
Publikováno v:
MethodsX, Vol 13, Iss , Pp 102807- (2024)
The method presented herein is associated with the Lab Resource article titled “Generation of αMHC-EGFP knock-in in human pluripotent stem cell line, SNUe003-A-3, using CRISPR/CAS9-based gene targeting” [1]. The cardiac muscle-specific protein,
Externí odkaz:
https://doaj.org/article/1e2047556a094d1ba87b903328e9c34c
Autor:
Minhan Park, Seunghye Lee, Haebum Lee, Ma. Cristine Faye J. Denna, Jiho Jang, Dahye Oh, Min-Suk Bae, Kyoung-Soon Jang, Kihong Park
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25310- (2024)
Toxicological data and exposure levels of fine particulate matters (PM2.5) are necessary to better understand their health effects. Simultaneous measurements of PM2.5 oxidative potential (OP) and cell toxicity in urban areas (Beijing, China and Gwang
Externí odkaz:
https://doaj.org/article/871cdda1832d4d19ba69ac491525691f
Autor:
A-Hyeon Kim, Ha Myoung Lee, Hong-Sik Kim, Juwon Jung, Hyewon Seol, Eunmi Choi, Seongeun Lee, Young Min Choi, Jong Kwan Jun, Han-Soo Kim, Jiho Jang
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103064- (2023)
TUBB3 is a structural neuronal protein important for multiple neuronal functions including axonal guidance and maturation. This study aimed to generate a human pluripotent stem cell (hPSC) line with a TUBB3-mCherry reporter using CRISPR/SpCas9 nuclea
Externí odkaz:
https://doaj.org/article/959aefd8c6cf46638af3fd2da0db7f09
Autor:
Ha Myoung Lee, A-Hyeon Kim, Sunsook Hwang, Juwon Jung, Hyewon Seol, Jin Jea Sung, Seung Min Jeong, Young Min Choi, Jong Kwan Jun, Han-Soo Kim, Jiho Jang
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102779- (2022)
The cardiac muscle-specific protein, α-myosin heavy chain (αMHC), is a major component of cardiac muscle filaments involved in cardiac muscle contraction. Here, we established an αMHC-enhanced fluorescent protein (EGFP) knock-in human pluripotent
Externí odkaz:
https://doaj.org/article/9a6f07bb982e4ad38f547b12302c91ad
Autor:
Eul Sik Jung, Ji Hun Kim, Mi-Yoon Chang, Wonjun Hong, Zhejiu Quan, Seung Hyun Kim, Seungkwon You, Dae-Sung Kim, Jiho Jang, Sang-Hun Lee, Hyongbum Henry Kim, Hoon Chul Kang
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102664- (2022)
X-linked adrenoleukodystrophy (ALD) caused by the ABCD1 mutation, is the most common inherited peroxisomal disease. Previously, we generated an ALD patient-derived SCHi001-A iPSC model. In this study, we have performed the first genome editing of ALD
Externí odkaz:
https://doaj.org/article/5d11b80c4cb347fb883062844b1ab6e8
Autor:
Juwon Jung, Sunsook Hwang, Hyewon Seol, A-Hyeon Kim, Ha Myoung Lee, Jin Jea Sung, Seung Min Jeong, Young Min Choi, Jong Kwan Jun, Dong-wook Kim, Jiho Jang
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102321- (2021)
Brachyury is an embryonic nuclear transcription factor required for mesoderm formation and differentiation. Here, we introduced an mCherry reporter into the C-terminus of Brachyury in the human pluripotent stem cell line SNUhES3 using the CRISPR/Cas9
Externí odkaz:
https://doaj.org/article/8bfca9068611400c900d16f80a1908c4
Publikováno v:
Stem Cell Reports, Vol 9, Iss 2, Pp 629-641 (2017)
Summary: Human embryonic stem cells (hESCs) hold great promise for the treatment of many incurable diseases. Sirtuin1 (SIRT1), a class III histone deacetylase, is abundantly expressed in hESCs and is known to regulate early differentiation and telome
Externí odkaz:
https://doaj.org/article/3db8e56f83b14e35af8473dbda06ef8f
Autor:
Sanghyun Park, Jeong-Eun Yoo, Dongjin R. Lee, Jiho Jang, Myung Soo Cho, Dae-Sung Kim, Dong-Wook Kim
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
Pituitary homeobox 3 (Pitx3) is a key transcription factor that plays an important role in the development and maintenance of midbrain dopaminergic (mDA) neurons. Here, we established a PITX3-mCherry knock-in reporter human embryonic stem cell (hESC)
Externí odkaz:
https://doaj.org/article/eebc35d729ab47f993ce88760d4f260e
Autor:
Jiho Jang, Sangjun Park, Hye Jin Hur, Hyun-Ju Cho, Inhwa Hwang, Yun Pyo Kang, Isak Im, Hyunji Lee, Eunju Lee, Wonsuk Yang, Hoon-Chul Kang, Sung Won Kwon, Je-Wook Yu, Dong-Wook Kim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
The mechanism underlying neuroinflammation in X-linked adrenoleukodystrophy (ALD) is poorly understood. Here authors identify aberrant production of 25-hydroxycholesterol (25-HC) in ALD patient-derived cells, and show that 25-HC mediates neuroinflamm
Externí odkaz:
https://doaj.org/article/20c6b5bb71f44d98aad419a4cf590e6d
Autor:
Minhan Park, Yujue Wang, Jihyo Chong, Haebum Lee, Jiho Jang, Hangyul Song, Nohhyeon Kwak, Lucille Joanna S. Borlaza, Hyunok Maeng, Enrique Mikhael R. Cosep, Ma. Cristine Faye J. Denna, Shiyi Chen, Ilhwa Seo, Min-Suk Bae, Kyoung-Soon Jang, Mira Choi, Young Hwan Kim, Moonhee Park, Jong-Sik Ryu, Sanghee Park, Min Hu, Kihong Park
Publikováno v:
Atmosphere, Vol 11, Iss 3, p 292 (2020)
We performed simultaneous measurements of chemical compositions of fine particles in Beijing, China and Gwangju, Korea to better understand their sources during winter haze period. We identified PM2.5 events in Beijing, possibly caused by a combinati
Externí odkaz:
https://doaj.org/article/babddb9f48f74990acbbfe095142a291