Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jihane Pakradouni"'
Autor:
Renaud Sabatier, Cécile Vicier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Nicolas Isambert, Florence Dalenc, Marie Robert, Christelle Levy, Jihane Pakradouni, José Adelaïde, Max Chaffanet, Patrick Sfumato, Emilie Mamessier, François Bertucci, Anthony Goncalves
Publikováno v:
Molecular Oncology, Vol 16, Iss 10, Pp 2057-2070 (2022)
The phosphatidylinositol‐3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway is frequently activated in HER2‐negative breast cancer and may play a role in taxane resistance. The phase IB/II TAKTIC trial (NCT01980277) has shown that
Externí odkaz:
https://doaj.org/article/703ca5faef324c5b808393f820024f09
Autor:
Renaud Sabatier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Jihane Pakradouni, José Adelaide, Magali Provansal, Maria Cappiello, Frédérique Rousseau, Max Chaffanet, Daniel Birnbaum, Emilie Mamessier, Anthony Gonçalves, François Bertucci
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionThe poor prognosis of ovarian carcinoma (OvC) is due to the advanced stage at diagnosis, a high risk of relapse after first-line therapies, and the lack of efficient treatments in the recurrence setting. Circulating tumor DNA (ctDNA) anal
Externí odkaz:
https://doaj.org/article/e8ca0d11810341ec999c93a85f969100
Autor:
François Bertucci, Anthony Gonçalves, Arnaud Guille, José Adelaïde, Séverine Garnier, Nadine Carbuccia, Emilien Billon, Pascal Finetti, Patrick Sfumato, Audrey Monneur, Christophe Pécheux, Martin Khran, Serge Brunelle, Lenaïg Mescam, Jeanne Thomassin-Piana, Flora Poizat, Emmanuelle Charafe-Jauffret, Olivier Turrini, Eric Lambaudie, Magali Provansal, Jean-Marc Extra, Anne Madroszyk, Marine Gilabert, Renaud Sabatier, Cécile Vicier, Emilie Mamessier, Christian Chabannon, Jihane Pakradouni, Patrice Viens, Fabrice André, Gwenaelle Gravis, Cornel Popovici, Daniel Birnbaum, Max Chaffanet
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background The benefit of precision medicine based on relatively limited gene sets and often-archived samples remains unproven. PERMED-01 (NCT02342158) was a prospective monocentric clinical trial assessing, in adults with advanced solid can
Externí odkaz:
https://doaj.org/article/685cee8dc4e4477fb464978bcebb91ff
Molecular Profiles of Advanced Urological Cancers in the PERMED-01 Precision Medicine Clinical Trial
Autor:
Emilien Billon, Gwenaelle Gravis, Arnaud Guille, Nadine Carbuccia, Jose Adelaide, Séverine Garnier, Pascal Finetti, Emilie Denicolaï, Patrick Sfumato, Serge Brunelle, Jeanne Thomassin-Piana, Géraldine Pignot, Jochen Walz, Christian Chabannon, Jihane Pakradouni, Renaud Sabatier, Cécile Vicier, Cornel Popovici, Emilie Mamessier, Anthony Gonçalves, Daniel Birnbaum, Max Chaffanet, François Bertucci
Publikováno v:
Cancers, Vol 14, Iss 9, p 2275 (2022)
Introduction. The prognosis of advanced urological cancers (AUC) remains unfavorable, and few data are available regarding precision medicine. Methods: the PERMED-01 prospective clinical trial assessed the impact of molecular profiling in adults with
Externí odkaz:
https://doaj.org/article/bc983ea1279a4b5fa1c28af700686434
Publikováno v:
Cancers, Vol 14, Iss 7, p 1794 (2022)
Cancer patients commonly experience psychological distress that may increase with the current COVID-19 pandemic. This prospective study aimed to measure post-traumatic stress disorder (PTSD) and anxiety in cancer patients following France’s first C
Externí odkaz:
https://doaj.org/article/2cc2cd97d1cf4875bc611a43fe61ffce
Autor:
Alexia Lopresti, Claire Acquaviva, Laurys Boudin, Pascal Finetti, Séverine Garnier, Anaïs Aulas, Maria Lucia Liberatoscioli, Olivier Cabaud, Arnaud Guille, Alexandre de Nonneville, Quentin Da Costa, Emilie Denicolai, Jihane Pakradouni, Anthony Goncalves, Daniel Birnbaum, François Bertucci, Emilie Mamessier
Publikováno v:
Cancers, Vol 14, Iss 4, p 932 (2022)
Circulating tumor cells have a strong potential as a quasi-non-invasive tool for setting up a precision medicine strategy for cancer patients. Using a second-generation “filtration-based” technology to isolate CTCs, the Screencell™ technology (
Externí odkaz:
https://doaj.org/article/c780956bbd3d49afa5aab1954d4af3b0
Autor:
Stéphane Fattori, Laurent Gorvel, Samuel Granjeaud, Philippe Rochigneux, Marie-Sarah Rouvière, Amira Ben Amara, Nicolas Boucherit, Magali Paul, Marie Mélanie Dauplat, Jeanne Thomassin-Piana, Maria Paciencia-Gros, Morgan Avenin, Jihane Pakradouni, Julien Barrou, Emmanuelle Charafe-Jauffret, Gilles Houvenaeghel, Eric Lambaudie, François Bertucci, Anthony Goncalves, Carole Tarpin, Jacques A. Nunès, Raynier Devillier, Anne-Sophie Chretien, Daniel Olive
Publikováno v:
Cancers, Vol 13, Iss 3, p 441 (2021)
The rationale for therapeutic targeting of Vδ2+ γδ T cells in breast cancer is strongly supported by in vitro and murine preclinical investigations, characterizing them as potent breast tumor cell killers and source of Th1-related cytokines, backi
Externí odkaz:
https://doaj.org/article/8aaab227ed064d5f9cd639bcf95b1796
Autor:
Jihane Pakradouni, Wilfried Le Goff, Claire Calmel, Bénédicte Antoine, Elise Villard, Eric Frisdal, Marianne Abifadel, Joan Tordjman, Christine Poitou, Dominique Bonnefont-Rousselot, Randa Bittar, Eric Bruckert, Karine Clément, Bruno Fève, Cécile Martinerie, Maryse Guérin
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66788 (2013)
OBJECTIVE:Evidence points to a founder of the multifunctional CCN family, NOV/CCN3, as a circulating molecule involved in cardiac development, vascular homeostasis and inflammation. No data are available on the relationship between plasma NOV/CCN3 le
Externí odkaz:
https://doaj.org/article/b2e4f187d15a43ef969468e840ebe89c
Autor:
Jihane Pakradouni, Jean-Marie Boher, Charlène Villaron-Goetgheluck, Patrice Viens, Sarah Calvin, Pierre Dantin, Sarah Cuvelier, Angela Granata, Sabine Furst, Sebastien Justafré, Didier Blaise
Publikováno v:
Bone Marrow Transplantation
Bone Marrow Transplantation, 2021, 56 (11), pp.2755-2762. ⟨10.1038/s41409-021-01401-y⟩
Bone Marrow Transplantation, 2021, 56 (11), pp.2755-2762. ⟨10.1038/s41409-021-01401-y⟩
International audience; A need for social support is often expressed after hospitalization post HSCT. Emotional support and positive psychological constructs play an important role in post-HSCT recovery. Interventions generating positive affect can i
Autor:
Stéphane FATTORI, Aude Le Roy, Jemila Houacine, Lucie Robert, Riad Abes, Laurent Gorvel, Samuel Granjeaud, Marie-Sarah Rouvière, Amira Ben Amara, Nicolas Boucherit, Carole Tarpin, Jihane Pakradouni, Emmanuelle Charafe-Jauffret, Julien Barrou, Gilles Houvenaeghel, Eric Lambaudie, François Bertucci, Philippe Rochigneux, Anthony Gonçalves, Arnaud Foussat, Anne-Sophie Chrétien, Daniel Olive
Publikováno v:
Cancer Research. 83:3239-3239
Background: PD-1 blockade (αPD-1) has shown limited efficacy in breast & gynecologic cancers. In other types of solid tumor, regulatory T cells (Tregs) harbouring markers of highly suppressive effector Tregs (eTregs) correlates with poor responses t