Výsledky vyhledávání - "Jihane Mriouah"

Akademický článek

Synergistic antitumor effect between gefitinib and fractionated irradiation in anaplastic oligodendrogliomas cannot be predicted by the Egfr signaling activity.

Autor: Sophie Pinel, Jihane Mriouah, Marc Vandamme, Alicia Chateau, François Plénat, Eric Guérin, Luc Taillandier, Valérie Bernier-Chastagner, Jean-Louis Merlin, Pascal Chastagner

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e68333 (2013)

In high-grade gliomas, the identification of patients that could benefit from EGFR inhibitors remains a challenge, hindering the use of these agents. Using xenografts models, we evaluated the antitumor effect of the combined treatment "gefitinib + ra

Externí odkaz: https://doaj.org/article/8c51b36a3e4b40fa84e118415674f46d

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Preclinical studies of pegylated- and non-pegylated liposomal forms of doxorubicin as radiosensitizer on orthotopic high-grade glioma xenografts

Autor: Sophie Pinel, Muriel Barberi-Heyob, Pascal Chastagner, H. Sudour, Valérie Bernier-Chastagner, Jihane Mriouah

Publikováno v: Pharmaceutical Research
Pharmaceutical Research, American Association of Pharmaceutical Scientists, 2015, 32 (1), pp.158-166. ⟨10.1007/s11095-014-1452-x⟩

International audience; Free doxorubicin (DXR) is not currently used to treat brain tumors because (i) the blood-brain barrier limits the drug deposition into the brain (ii) lethal toxic effects occur when combined with radiation therapy. Since encap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4b402018e4a5e8c3b92f6c4d376194
https://hal.archives-ouvertes.fr/hal-01079724

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Abstract 5143: Fusogenic targeted liposomes: novel nanotherapy for specific treatment of prostate cancer

Autor: Andries Zijlstra, John D. Lewis, Susan Richter, Rae Lynn Nesbitt, Desmond Pink, Roy Duncan, Deborah Sosnowski, Frank Wuest, Melinda Wuest, Jihane Mriouah

Publikováno v: Cancer Research. 77:5143-5143

Metastatic or castrate-resistant prostate cancer is the second-leading cause of cancer mortality in males. In the past 3 years, chemotherapies have extended survival, but efficacy is limited by dose-limiting toxicities due to suboptimal biodistributi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c67ec597931b4e274d0818e65733f58
https://doi.org/10.1158/1538-7445.am2017-5143

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PTEN expression is involved in the invasive properties of HNSCC: a key protein to consider in locoregional recurrence

Autor: Béatrice Faivre, Jihane Mriouah, François Plénat, Myriem Gargouri, Cédric Boura

Publikováno v: International Journal of Oncology
International Journal of Oncology, Spandidos Publications, 2014, 44 (3), pp.709-716. ⟨10.3892/ijo.2013.2219⟩

International audience; Specific phenotypic effects of PTEN in head and neck squamous cell carcinoma (HNSCC) remain poorly defined without a direct causal connection between the loss of PTEN function and the progression of cancer. Here, we describe a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ceabbf7ab86fc306a3ab4d13e618229
https://pubmed.ncbi.nlm.nih.gov/24366426

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Tumor vascular responses to antivascular and antiangiogenic strategies: looking for suitable models

Autor: Muriel Barberi-Heyob, Cédric Boura, Thierry Bastogne, Magalie Thomassin, Béatrice Faivre, Jihane Mriouah, Dominique Dumas

Publikováno v: Trends in Biotechnology
Trends in Biotechnology, 2012, 30 (12), pp.649-658. ⟨10.1016/j.tibtech.2012.08.006⟩
Trends in Biotechnology, Elsevier, 2012, 30 (12), pp.649-658. ⟨10.1016/j.tibtech.2012.08.006⟩

International audience; Antiangiogenic and vascular disrupting agents are in the current cancer therapeutic armamentarium. A better understanding of the intricate mechanisms ruling neovessel survival within tumors during or after treatment is needed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4b05528490e5b14595edcc09ca69b4
https://hal.science/hal-00726417

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Cellular response to cetuximab in PTEN-silenced head and neck squamous cell carcinoma cell line

Autor: Anne-Sophie Chretien, Sophie Pinel, Béatrice Faivre, Jihane Mriouah, Cédric Boura, Jean-Louis Merlin, Alexandre Fifre

Publikováno v: International Journal of Oncology. 37

The implication of loss of PTEN expression in resistance to targeted therapy has already been described in many tumor types. The absence of response to anti-EGFR agents in PTEN-deficient tumors relies on persistent activation of signaling pathways do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87dacb9c07cee677ca20f06be13e7594
https://doi.org/10.3892/ijo_00000809

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Resistance to cetuximab – implication of PTEN expression in the cellular sensitivity to cetuximab (Erbitux®) of Head and Neck Squamous Cell Carcinoma (HNSCC)

Autor: Cédric Boura, C. Chartier, Alexandre Fifre, I. Fries, C. Ramacci, Jean-Louis Merlin, Béatrice Faivre, Jihane Mriouah

Publikováno v: European Journal of Cancer Supplements. 6:112

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c7f58ef607f6e360abdcf7a0e9ad642
https://doi.org/10.1016/s1359-6349(08)71601-x

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