Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jigna Bhalla"'
Publikováno v:
Gynecologic Oncology. 162:S111-S112
Objectives: Olaparib is approved as a first line (1L) maintenance (mtx) option, as monotherapy for BRCA mutated (BRCAm) ovarian cancer (OC) and in combination with bevacizumab (Bev) for homologous recombination deficient (HRD) OC. Niraparib monothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a3f8d56c6a5e99f66ac1357d32e4743
https://doi.org/10.1016/s0090-8258(21)00854-4
https://doi.org/10.1016/s0090-8258(21)00854-4
Autor:
Emma V. Jones, Jigna Bhalla, Alison Stopeck, Lea N. Baer, Jules Cohen, Patricia A. Thompson, Christina Preece, Jinyu Li, Andrew J. Pierce
Publikováno v:
Journal of Clinical Oncology. 38:e12642-e12642
e12642 Background: Translesion synthesis (TLS) of DNA by specialized polymerases (POLs) and REV1, a scaffold protein that recruits other TLS DNA POLs for nascent strand extension, experimentally enable tumor cells to replicate through DNA damage. TLS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcae00a24e48cba2071ddc9b28a51c5
https://doi.org/10.1200/jco.2020.38.15_suppl.e12642
https://doi.org/10.1200/jco.2020.38.15_suppl.e12642