Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jiezhong, Yu"'
Autor:
Jingwen Yu, Bingtao Mu, Minfang Guo, Chunyun Liu, Tao Meng, Yuqing Yan, Lijuan Song, Jiezhong Yu, Gajendra Kumar, Cungen Ma
Publikováno v:
Folia Neuropathologica, Vol 61, Iss 3, Pp 273-290 (2023)
Astragaloside IV (AST IV), a major saponin component and active ingredient isolated from Astragalus membranaceus, has been well known to exhibit neuroprotective effects on diverse models of neurological diseases. Accumulating evidence suggests that d
Externí odkaz:
https://doaj.org/article/50700f6014c246de91738b988ac4ee3e
Autor:
Wenhui Zhu, Weifen Li, Jian Jiang, Dilong Wang, Xinliang Mao, Jin Zhang, Xunzhi Zhang, Jinlong Chang, Peijia Yao, Xiuyan Yang, Clive Da Costa, Ying Zhang, Jiezhong Yu, Huiliang Li, Shupeng Li, Xinjin Chi, Ningning Li
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Depression is a common recurrent psychiatric disorder with a high lifetime prevalence and suicide rate. At present, although several traditional clinical drugs such as fluoxetine and ketamine, are widely used, medications with a high efficiency and r
Externí odkaz:
https://doaj.org/article/19c48917f81e41e6a01af424ee77399b
Autor:
Wenyue Wei, Yuyin Wang, Jing Zhang, Qingfang Gu, Xiaoqin Liu, Lijuan Song, Zhi Chai, Minfang Guo, Jiezhong Yu, Cungen Ma
Publikováno v:
Folia Neuropathologica, Vol 59, Iss 1, Pp 32-49 (2021)
Alzheimer’s disease (AD) is a severe neurodegenerative disorder of the central nervous system (CNS) characterized by neuron loss and dementia. Previous abundant evidence demonstrates that the first critical step in the course of AD is the state of
Externí odkaz:
https://doaj.org/article/9f9d3da2cd2c4fa1b5ed0ab71fc8125a
Autor:
Jian Jiang, Jun Ju, Liang Luo, Ze Song, Huanquan Liao, Xiuyan Yang, Shoupeng Wei, Dilong Wang, Wenhui Zhu, Jinlong Chang, Junzhe Ma, Hao Hu, Jiezhong Yu, Huiqing Wang, Sheng-Tao Hou, Shupeng Li, Huiliang Li, Ningning Li
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Depressive disorder is defined as a psychiatric disease characterized by the core symptoms of anhedonia and learned helplessness. Currently, the treatment of depression still calls for medications with high effectiveness, rapid action, and few side e
Externí odkaz:
https://doaj.org/article/7de048154ee4448ba892fab1061e8afe
Autor:
Jingwen Yu, Minfang Guo, Yanhua Li, Huiyu Zhang, Zhi Chai, Qing Wang, Yuqing Yan, Jiezhong Yu, Chunyun Liu, Guangxian Zhang, Ma Cungen
Publikováno v:
Folia Neuropathologica, Vol 57, Iss 2, Pp 170-181 (2019)
Astragaloside IV (AST-IV) is a major active ingredient of astragalus, with a neuroprotective effect. The current study is aimed to investigate the impact of AST-IV on the M1/M2 microglial activation in response to lipopolysaccharide (LPS) stimulation
Externí odkaz:
https://doaj.org/article/045fddd11a3a45d9952a1552f8c74266
Autor:
Rui-Yuan Pan, Jing Zhang, Jinlei Wang, Yingyi Wang, Zhihui Li, Yang Liao, Yajin Liao, Chenggang Zhang, Zhiqiang Liu, Lijuan Song, Jiezhong Yu, Zengqiang Yuan
Publikováno v:
Nature Aging. 2:1024-1039
Autor:
Jiezhong Yu, Yuqing Yan, Qingfang Gu, Gajendra Kumar, Hongqiang Yu, Yijin Zhao, Chunyun Liu, Ye Gao, Zhi Chai, Jasleen Chumber, Bao-Guo Xiao, Guang-Xian Zhang, Han-Ting Zhang, Yuqiang Jiang, Cun-Gen Ma
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Alzheimer’s disease (AD) is a chronic progressive neurodegenerative disease. Its mechanism is still not clear. Majority of research focused on the central nervous system (CNS) changes, while few studies emphasize on peripheral immune system modulat
Externí odkaz:
https://doaj.org/article/4c85771925654c6689dbb879bc970bd0
Autor:
Jingwen, Yu, Minfang, Guo, Pengwei, Yang, Yanhua, Li, Chunyun, Liu, Lijuan, Song, Zhi, Chai, Jiezhong, Yu, Cungen, Ma
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 38(11)
Objective To investigate the protective effect and mechanism of astragaloside IV (AST4) on H
Autor:
Minfang, Guo, Huiyu, Zhang, Jingwen, Yu, Peijun, Zhang, Yuyin, Wang, Wenyue, Wei, Lijuan, Song, Zhi, Chai, Jiezhong, Yu, Cungen, Ma
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 38(7)
Objective To investigate the effect of Fasudil on H
Autor:
Han Hu, Shuoshuo Li, Jifeng Guo, Xiangxi Kong, Cungen Ma, Mingtao Li, Xiaoheng Li, Jiezhong Yu, Jinbo Cheng, Jianke Li, Nannan Yang, Zengqiang Yuan, Lixia Qin, Yajin Liao, Yuan Dong, Beisha Tang
Publikováno v:
Autophagy
Microglial activation-induced neuroinflammation is closely associated with the development of Parkinson disease (PD). Macroautophagy/autophagy regulates many biological processes, but the role of autophagy in microglial activation during PD developme