Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jieyuan Wu"'
Autor:
Hengxu Mao, Yaoyun Kuang, Du Feng, Xiang Chen, Lin Lu, Wencheng Xia, Tingting Gan, Weimeng Huang, Wenyuan Guo, Hancun Yi, Yirong Yang, Zhuohua Wu, Wei Dai, Hui Sun, Jieyuan Wu, Rui Zhang, Shenqing Zhang, Xiuli Lin, Yuxuan Yong, Xinling Yang, Hongyan Li, Wenjun Wu, Xiaoyun Huang, Zhaoxiang Bian, Hoi Leong Xavier Wong, Xin-Lu Wang, Michael Poppell, Yi Ren, Cong Liu, Wen-Quan Zou, Shengdi Chen, Ping-Yi Xu
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2024)
Abstract Background Seed amplification assays (SAA) enable the amplification of pathological misfolded proteins, including α-synuclein (αSyn), in both tissue homogenates and body fluids of Parkinson’s disease (PD) patients. SAA involves repeated
Externí odkaz:
https://doaj.org/article/d23c5a987e634c22a6f7e6300ff16365
Autor:
La Xiang, Xuanxuan Zhang, Yanyan Lei, Jieyuan Wu, Guangru Yan, Wei Chen, Shizhong Li, Wenzhao Wang, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang
Publikováno v:
Biotechnology for Biofuels and Bioproducts, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background Polyketide synthases (PKSs) are classified into three types based on their enzyme structures. Among them, type III PKSs, catalyzing the iterative condensation of malonyl-coenzyme A (CoA) with a CoA-linked starter molecule, are imp
Externí odkaz:
https://doaj.org/article/8ee8377fcd844700812f097e38a76a32
Autor:
Jieyuan Wu, Chaoning Liang, Yufei Li, Yueting Zeng, Xu Sun, Peixia Jiang, Wei Chen, Dandan Xiong, Jian‐Ming Jin, Shuang‐Yan Tang
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 3, Pp n/a-n/a (2024)
Abstract Optimal transcriptional regulatory circuits are expected to exhibit stringent control, maintaining silence in the absence of inducers while exhibiting a broad induction dynamic range upon the addition of effectors. In the Plac/LacI pair, the
Externí odkaz:
https://doaj.org/article/e0b35caf83fc421dac2b50b4cc661bc3
Autor:
Yanyan Lei, Wei Chen, La Xiang, Jieyuan Wu, Zhen Zhen, Jian-Ming Jin, Chaoning Liang, Shuang-Yan Tang
Publikováno v:
Metabolic engineering. 74
Elegant controllable protein degradation tools have great applications in metabolic engineering and synthetic biology designs. SspB-mediated ClpXP proteolysis system is well characterized, and SspB acts as an adaptor tethering ssrA-tagged substrates
Publikováno v:
Journal of Agricultural and Food Chemistry. 68:10772-10779
The biosynthetic efficiency of curcumin, a highly bioactive compound from the plant Curcuma longa, needs to be improved. In this study, we performed host cell and biosynthetic pathway engineering to improve curcumin biosynthesis. Using in vivo-direct
Publikováno v:
Journal of agricultural and food chemistry. 68(39)
The biosynthetic efficiency of curcumin, a highly bioactive compound from the plant
Autor:
Dandan Xiong, Wei Wang, Chaoning Liang, Jieyuan Wu, Wenzhao Wang, Jian-Ming Jin, Shuang-Yan Tang, Shikun Lu
Publikováno v:
Metabolic Engineering. 40:115-123
Overexpressing key enzymes of biosynthetic pathways for overproduction of value-added products usually imposes metabolic burdens on cells, which can be circumvented by improving the key enzyme activities. p-Coumarate: CoA ligase (4CL) is a critical e
Autor:
A. John Hart, Adam G. Stevens, Jieyuan Wu, Jenna Garber, Lillian Chin, Chad Robert Archer, Casey Boyle, C. Ryan Oliver, Matthieu Kirchmeyer, Erik S. Polsen
Publikováno v:
3D Printing and Additive Manufacturing. 3:226-235
Additive manufacturing by layerwise photopolymerization, commonly called stereolithography (SLA), is attractive due to its high resolution and diversity of materials chemistry. However, traditional SLA methods are restricted to planar substrates and
Autor:
Jian-Ming Jin, Xuanxuan Zhang, Zhe Wu, Shuang-Yan Tang, Chaoning Liang, Shanshan Mu, Jieyuan Wu
Publikováno v:
Metabolic engineering. 57
To mimic the delicately regulated metabolism in nature for improved efficiency, artificial and customized regulatory components for dynamically controlling metabolic networks in multiple layers are essential in laboratory engineering. For this purpos
Autor:
Xiongwei Deng, Zhongliang Zheng, Jieyuan Wu, Li Zhu, Wei Bao, Guolin Zou, Meizhi Weng, Yan Jia, Yongjun Cai
Publikováno v:
Biochemical and Biophysical Research Communications. 465:580-586
Nattokinase (NK), a bacterial serine protease from Bacillus subtilis var. natto, is a potential cardiovascular drug exhibiting strong fibrinolytic activity. To broaden its commercial and medical applications, we constructed a single-mutant (I31L) and