Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jieyou Zhang"'
Autor:
Lijuan Zhang, Kai Zhang, Jieyou Zhang, Jinrong Zhu, Qing Xi, Huafeng Wang, Zimu Zhang, Yingnan Cheng, Guangze Yang, Hongkun Liu, Xiangdong Guo, Dongmei Zhou, Zhenyi Xue, Yan Li, Qi Zhang, Yurong Da, Li Liu, Zhinan Yin, Zhi Yao, Rongxin Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The role of common fragile site associated genes such as FATS in the immune system is unclear. Here the authors show that deletion of Fats in a mouse tumour model leads to reduced tumour growth and change of macrophage phenotype from an M2-like to M1
Externí odkaz:
https://doaj.org/article/0d57473fefd244258eb00c325b39d0e2
Autor:
Li Liu, Yan Li, Ying Chen, Qi Zhang, Lijuan Zhang, Chengzhi Wang, Qing Xi, Jieyou Zhang, Guangze Yang, Zimu Zhang, Xiangdong Guo, Jingyi Zhao, Zhenyi Xue, Yurong Da, Zhi Yao, Rongxin Zhang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Immune checkpoint blockade has emerged as a potential cancer immunotherapy. The “don’t eat me” signal CD47 in cancer cells binds signal regulatory protein-α on macrophages and prevents their phagocytosis. The role of miR-340 in panc
Externí odkaz:
https://doaj.org/article/6fb9c48de0f84bcf8e5d56c5cd0063d0
Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics
Autor:
Shuai Ma, Jieyou Zhang, Qiushi Guo, Cheng Cao, Kaiwen Bao, Ling Liu, Charlie Degui Chen, Zhe Liu, Jie Yang, Na Yang, Zhi Yao, Lei Shi
Publikováno v:
Cancer Letters. 530:29-44
The DNA damage response (DDR) pathway generally protects against genome instability, and defects in DDR have been exploited therapeutically in cancer treatment. We have reported that histone demethylase PHF8 demethylates TOPBP1 K118 mono-methylation
Autor:
Yurong Da, Xiangdong Guo, Guangze Yang, Lijuan Zhang, Hongkun Liu, Qing Xi, Dongmei Zhou, Yan Li, Qi Zhang, Li Liu, Jinrong Zhu, Jieyou Zhang, Rongxin Zhang, Huafeng Wang, Zhenyi Xue, Yingnan Cheng, Zhinan Yin, Zimu Zhang, Kai Zhang, Zhi Yao
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Common fragile sites (CFSs) are specific breakage-prone genomic regions and are present frequently in cancer cells. The (E2-independent) E3 ubiquitin-conjugating enzyme FATS (fragile site-associated tumor suppressor) has antitumor activity in cancer
Autor:
Rongxin Zhang, Xin Ran, Yingnan Cheng, Ying Chen, Guangze Yang, Lalit Chudal, Wei Chen, Yan Li, Yuping Ran, Li Liu, Jingyi Zhao, Zhi Yao, Qing Xi, Jieyou Zhang, Qi Zhang, Chengzhi Wang, Nil Kanatha Pandey, Lun Ma, Xiangdong Guo
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-3 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Autor:
Lijuan Zhang, Guangze Yang, Yurong Da, Qi Zhang, Jienv Lv, Xiangdong Guo, Yinghui Ren, Rongxin Zhang, Yan Li, Dongmei Zhou, Zimu Zhang, Jieyou Zhang, Zhi Yao, Ze-Han Liu, Qing Xi, Zhenyi Xue, Hongkun Liu
Publikováno v:
Journal of Cellular Biochemistry. 120:15695-15708
Muscle redox disturbances and oxidative stress have emerged as a common pathogenetic mechanism and potential therapeutic intervention in some muscle diseases. Parthenolide (PTL), a sesquiterpene lactone found in large amounts in the leaves of feverfe
Autor:
Jiao Zhao, Shanshan Tian, Qiushi Guo, Kaiwen Bao, Guohui Yu, Xiaodan Wang, Xilin Shen, Jieyou Zhang, Jiaxin Chen, Ying Yang, Ling Liu, Xiangchun Li, Jihui Hao, Na Yang, Zhe Liu, Ding Ai, Jie Yang, Yi Zhu, Zhi Yao, Shuai Ma, Kai Zhang, Lei Shi
Publikováno v:
Molecular Cell. 82:2571-2587.e9
The efficiency of homologous recombination (HR) in the repair of DNA double-strand breaks (DSBs) is closely associated with genome stability and tumor response to chemotherapy. While many factors have been functionally characterized in HR, such as TO
Autor:
Ying Chen, Lijuan Zhang, Ruijie Dong, Jieyou Zhang, Chao Gu, Guangze Yang, Rongxin Zhang, Jingyi Zhao, Xin Li, Chengzhi Wang, Xiangdong Guo, Qing Xi, Yan Li
Publikováno v:
International immunopharmacology. 97
Pancreatic cancer is a highly malignant cancer of the digestive tract. Studies have shown that in some types of cancer, a high level of microRNA-194-5p (miR-194-5p) is beneficial for controlling tumor progression, while in other cancers it plays a co
Autor:
Lijuan Zhang, Jieyou Zhang, Chengzhi Wang, Rongxin Zhang, Xiangdong Guo, Ying Chen, Qing Xi, Lijun Dong, Yan Li, Zhenyi Xue, Ruijie Dong, Jingyi Zhao, Xin Li, Guangze Yang, Dongmei Zhou
Publikováno v:
Pharmacology Research & Perspectives
Acute peritonitis is an acute inflammatory response of the peritoneal cavity to physical injury and chemical stimulation. Timely resolution of this response is critical to prevent further damage to the body, which can eventually lead to more severe c
Autor:
Qing Xi, Yan Li, Zhenyi Xue, Zhi Yao, Rongxin Zhang, Jieyou Zhang, Li Liu, Qi Zhang, Zimu Zhang, Yurong Da, Guangze Yang, Xiangdong Guo, Lijuan Zhang, Jingyi Zhao, Ying Chen, Chengzhi Wang
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundImmune checkpoint blockade has emerged as a potential cancer immunotherapy. The “don’t eat me” signalCD47in cancer cells binds signal regulatory protein-α on macrophages and prevents their phagocytosis. The role of miR-340 in pancrea