Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jiexia Yang"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/998a24a019f24bfdae28a7b198a5b81a
Autor:
Yimo Zeng, Hongke Ding, Xingwang Wang, Yanlin Huang, Ling Liu, Li Du, Jian Lu, Jing Wu, Yukun Zeng, Mingqin Mai, Juan Zhu, Lihua Yu, Wei He, Fangfang Guo, Haishan Peng, Cuize Yao, Yiming Qi, Yuan Liu, Fake Li, Jiexia Yang, Rong Hu, Jie Liang, Jicheng Wang, Wei Wang, Yan Zhang, Aihua Yin
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Genetic disorders often manifest as abnormal fetal or childhood development. Copy number variations (CNVs) represent a significant genetic mechanism underlying such disorders. Despite their importance, the effectiveness of clinica
Externí odkaz:
https://doaj.org/article/433d3f2043ea4df4a876a0f806b3fcd1
Autor:
Xiaoli Gong, Wei He, Wan Jin, Hongwei Ma, Gang Wang, Jiaxin Li, Yu Xiao, Yangyu Zhao, Qiong Chen, Huanhuan Guo, Jiexia Yang, Yiming Qi, Wei Dong, Meng Fu, Xiaojuan Li, Jiusi Liu, Xinghui Liu, Aihua Yin, Yi Zhang, Yuan Wei
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-46 (2024)
Abstract Background Preeclampsia, one of the most lethal pregnancy-related diseases, is associated with the disruption of uterine spiral artery remodeling during placentation. However, the early molecular events leading to preeclampsia remain unknown
Externí odkaz:
https://doaj.org/article/07fbf085e6484c66b31e784c915c50d2
Autor:
Hui Tang, Jingjing Hu, Ling Liu, Lijuan Lv, Jian Lu, Jiexia Yang, Jiaqi Lu, Zhenhui Chen, Chaoxiang Yang, Dan Chen, Jintao Fu, Jing Wu
Publikováno v:
Molecular Cytogenetics, Vol 16, Iss 1, Pp 1-8 (2023)
Abstract Background Down syndrome myeloid hyperplasia includes transient abnormal myelopoiesis (TAM) and the myeloid leukemia associated with Down syndrome (ML-DS). The mutation of GATA1 gene is essential in the development of Down syndrome combined
Externí odkaz:
https://doaj.org/article/6275bd30a41d48e39dd0a7309fb94b4e
Autor:
Yaping Hou, Jiexia Yang, Fuli Deng, Fanghua Wang, Haishan Peng, Fangfang Guo, Dongmei Wang, Aihua Yin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract To determine the association between cell-free DNA fetal fraction (cffDNA) and various prenatal characters to better guide the clinical application of noninvasive prenatal screening (NIPS), a retrospective cohort study of 27,793 women with s
Externí odkaz:
https://doaj.org/article/98c1f0b35b7e4122a5a9881c2fe25b8c
Autor:
Wei He, Yi Zhang, Kai Wu, Yunan Wang, Xin Zhao, Lijuan Lv, Congmian Ren, Jiaqi Lu, Jiexia Yang, Aihua Yin, Guocheng Liu
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 43, Iss 2 (2023)
AbstractBackground In the current study, we sought to characterise the methylation haplotypes and nucleosome positioning patterns of placental DNA and plasma cell-free DNA of pregnant women with early-onset preeclampsia using whole genome bisulphite
Externí odkaz:
https://doaj.org/article/ead937da80d248a1aab69a09158a1cf5
Publikováno v:
Molecular Cytogenetics, Vol 14, Iss 1, Pp 1-6 (2021)
Abstract Background Trisomy 16 (T16) is thought to be the most frequent chromosome abnormality at conception, which is often associated with a high risk of abnormal outcomes. Methods A retrospective analysis of 14 cases with high risk of T16 by nonin
Externí odkaz:
https://doaj.org/article/c747af9b135247c4ad127cd33560ae9b
Autor:
Jiexia Yang, Jing Wu, Haishan Peng, Yaping Hou, Fangfang Guo, Dongmei Wang, Haoxin Ouyang, Yixia Wang, Aihua Yin
Publikováno v:
Human Genomics, Vol 15, Iss 1, Pp 1-8 (2021)
Abstract Objective To evaluate the performance of noninvasive prenatal testing (NIPT) and NIPT-PLUS for the detection of genome-wide microdeletion and microduplication syndromes (MMSs) at different sequencing depths. The NIPT sequencing depth was 0.1
Externí odkaz:
https://doaj.org/article/eef462c859354957a18f122e16392100
Autor:
Jia Li, Jiaqi Lu, Fengxia Su, Jiexia Yang, Jia Ju, Yu Lin, Jinjin Xu, Yiming Qi, Yaping Hou, Jing Wu, Wei He, Zhengtao Yang, Yujing Wu, Zhuangyuan Tang, Yingping Huang, Guohong Zhang, Ying Yang, Zhou Long, Xiaofang Cheng, Ping Liu, Jun Xia, Yanyan Zhang, Yicong Wang, Fang Chen, Jianguo Zhang, Lijian Zhao, Xin Jin, Ya Gao, Aihua Yin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Non-invasive prenatal diagnosis (NIPD) can identify monogenic diseases early during pregnancy with negligible risk to fetus or mother, but the haplotyping methods involved sometimes cannot infer parental inheritance at heterozygous matern
Externí odkaz:
https://doaj.org/article/083ef07e01a34220ac88b11dd15e9bf1
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Background Small subchromosomal deletions and duplications caused by copy number variants (CNVs) can now be detected with noninvasive prenatal testing (NIPT) technology. However, the clinical utility and validity of this screening for CNVs a
Externí odkaz:
https://doaj.org/article/8053af7e10cb457ea3f6a1b06dd02996