Myeloid-specific Hdac10 deletion protects against LPS-induced acute lung injury via P62 acetylation at lysine 165

Autor: Yuanyuan Xiang, Yu Zhong, Xianwen Lai, Zhenfu Fang, Guomei Su, Yingying Lv, Xiantong Tang, Lihuan Ouyang, Xiao Gao, Hongying Zheng, Lilin He, Jialong Chen, Jiewen Huang, Tianwen Lai

Publikováno v: Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)

Abstract Background Aberrant activation of macrophages is associated with pathogenesis of acute lung injury (ALI). However, the potential pathogenesis has not been explored. Objectives We aimed to identify whether histone deacetylase (HDAC) 10 is inv

Externí odkaz: https://doaj.org/article/f4327818ba574e83a1fc119d2a71b6e5

Epithelial SIRT6 governs IL-17A pathogenicity and drives allergic airway inflammation and remodeling

Autor: Jingyun Quan, Xiaoxia Wen, Guomei Su, Yu Zhong, Tong Huang, Zhilin Xiong, Jiewen Huang, Yingying Lv, Shihai Li, Shuhua Luo, Chaole Luo, Xin Cai, Xianwen Lai, Yuanyuan Xiang, Song Guo Zheng, Yiming Shao, Haitao Lin, Xiao Gao, Jing Tang, Tianwen Lai

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Abstract Dysregulation of IL-17A is closely associated with airway inflammation and remodeling in severe asthma. However, the molecular mechanisms by which IL-17A is regulated remain unclear. Here we identify epithelial sirtuin 6 (SIRT6) as an epigen

Externí odkaz: https://doaj.org/article/e3a288d3476c4dd08ea3736c3ba24a6a

Immunological evaluation of patients with Alzheimer's disease based on mitogen-stimulated cytokine productions and mitochondrial DNA indicators

Autor: Jiewen Huang, Zhen Song, Beiwen Wei, Qingtian Li, Ping Lin, Hui Li, Ke Dong

Publikováno v: BMC Psychiatry, Vol 23, Iss 1, Pp 1-8 (2023)

Abstract Background Based on its objective characteristics, laboratory markers have always been the research direction of clinical diagnosis and assessment of mental disorders including Alzheimer's disease. Methods MTT Colorimetric Assay, ELISA, and

Externí odkaz: https://doaj.org/article/c9ce6c1907164e6faf80f27ba5e79e4b

Predicting a Failure of Public Speaking Performance Using Multidimensional Assessment

Autor: David Antonio Gómez Jáuregui, Jiewen Hua, Laurence Devillers, Mariette Soury, Tom Giraud, Jean-Claude Martin, Edith Filaire, Christine Le Scanff

Publikováno v: HAL
Journal of Sports Sciences
Journal of Sports Sciences, Taylor & Francis, 2016, pp.197-209
International journal of Sports Science and Coaching
International journal of Sports Science and Coaching, Multi-Science Publishing, 2016, 4 (4), ⟨10.17265/2332-7839/2016.04.003⟩

International audience; The present study aimed to examine multidimensional factors that contribute to a poor performance in a public speakingtask. An adapted version of the Trier Social Stress Test (TSST) as used to elicit psychosocial stress among

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939305ad4366f4e81f6e217f4c82a51f
https://hal.science/hal-01838646

Development and validation of a genomic nomogram based on a ceRNA network for comprehensive analysis of obstructive sleep apnea

Autor: Wang Liu, Xishi Sun, Jiewen Huang, Jinjian Zhang, Zhengshi Liang, Jinru Zhu, Tao Chen, Yu Zeng, Min Peng, Xiongbin Li, Lijuan Zeng, Wei Lei, Junfen Cheng

Publikováno v: Frontiers in Genetics, Vol 14 (2023)

Objectives: Some ceRNA associated with lncRNA have been considered as possible diagnostic and therapeutic biomarkers for obstructive sleep apnea (OSA). We intend to identify the potential hub genes for the development of OSA, which will provide a fou

Externí odkaz: https://doaj.org/article/75c50ec11d2d43f19c56a9e4cccbdf28