Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jieqiong You"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
As an essential mediator of inflammation and innate immunity, the receptor-interacting serine/threonine-protein kinase-2 (RIPK2) is responsible for transducing signaling downstream of the intracellular peptidoglycan sensors nucleotide oligomerization
Externí odkaz:
https://doaj.org/article/560b63b72c804f3c92fd2b663b10b1a0
Autor:
Xiaomeng Gao, Jieqiong You, Yanling Gong, Meng Yuan, Haiying Zhu, Liang Fang, Hong Zhu, Meidan Ying, Qiaojun He, Bo Yang, Ji Cao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1225-1239 (2022)
The dysregulation of transcription factors is widely associated with tumorigenesis. As the most well-defined transcription factor in multiple types of cancer, c-Myc can transform cells by transactivating various downstream genes. Given that there is
Externí odkaz:
https://doaj.org/article/9676cfef19674ac88ccbf278689f23d2
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2738-2748 (2021)
Synthetic lethality is a proven effective antitumor strategy that has attracted great attention. Large-scale screening has revealed many synthetic lethal genetic phenotypes, and relevant small-molecule drugs have also been implemented in clinical pra
Externí odkaz:
https://doaj.org/article/fe8825316a834fadaa7988ecdb6ab51e
Autor:
Bo Yang, Meidan Ying, Qiaojun He, Hong Zhu, Qinjie Weng, Ning Zhang, Zhanlei Chen, Wen Meng, Jieqiong You, Meng Yuan, Yanling Gong, Li Jiang, Rong Dong, Ji Cao
table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac1ea0b379b00b3bd14828e5cb42fe6
https://doi.org/10.1158/2326-6066.22539383.v1
https://doi.org/10.1158/2326-6066.22539383.v1
Autor:
Bo Yang, Meidan Ying, Qiaojun He, Hong Zhu, Qinjie Weng, Ning Zhang, Zhanlei Chen, Wen Meng, Jieqiong You, Meng Yuan, Yanling Gong, Li Jiang, Rong Dong, Ji Cao
M2 polarization of macrophages is essential for their function in immunologic tolerance, which might promote tumorigenesis. However, the molecular mechanism behind the polarization process is not fully understood. Given that several lines of evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b78967a986be3f2f76d0f4e77694da07
https://doi.org/10.1158/2326-6066.c.6549077.v1
https://doi.org/10.1158/2326-6066.c.6549077.v1
Autor:
Bo Yang, Meidan Ying, Qiaojun He, Hong Zhu, Qinjie Weng, Ning Zhang, Zhanlei Chen, Wen Meng, Jieqiong You, Meng Yuan, Yanling Gong, Li Jiang, Rong Dong, Ji Cao
Supplementary figures and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3eab86132654f77a118d497ed421f6
https://doi.org/10.1158/2326-6066.22539392
https://doi.org/10.1158/2326-6066.22539392
Autor:
Meidan Ying, Liang Fang, Jieqiong You, Meng Yuan, Bo Yang, Hong Zhu, Qiaojun He, Xiaomeng Gao, Yanling Gong, Haiying Zhu, Ji Cao
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1225-1239
The dysregulation of transcription factors is widely associated with tumorigenesis. As the most well-defined transcription factor in multiple types of cancer, c-Myc can transform cells by transactivating various downstream genes. Given that there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d9082ee9a4d49170996acee71176c82
https://doi.org/10.1016/j.apsb.2021.10.021
https://doi.org/10.1016/j.apsb.2021.10.021
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2738-2748 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Synthetic lethality is a proven effective antitumor strategy that has attracted great attention. Large-scale screening has revealed many synthetic lethal genetic phenotypes, and relevant small-molecule drugs have also been implemented in clinical pra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e354227b07a5cabcdb43f19242548e7
http://www.sciencedirect.com/science/article/pii/S221138352100006X
http://www.sciencedirect.com/science/article/pii/S221138352100006X
Autor:
Jieqiong You, Hong Zhu, Bo Yang, Zegao Jin, Jinxin Che, Fangjie Yan, Ji Cao, Binhui Chen, Qiaojun He, Jiangfeng Xie, Yongzhou Hu, Xiaowu Dong, Gang Cheng
Publikováno v:
Journal of Medicinal Chemistry. 64:8621-8643
The gain of cell motility is an essential prerequisite for cancer metastasis. The ubiquitin ligase subunit WD repeat and SOCS box-containing 1 (WSB1) has been demonstrated to regulate hypoxia-driven tumor cell migration. However, there is still a lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9274212d95ca378d8647168a5d01f76c
https://doi.org/10.1021/acs.jmedchem.1c00586
https://doi.org/10.1021/acs.jmedchem.1c00586
Publikováno v:
Current Drug Targets. 20:705-715
Background: Cellular senescence is generally understood as a permanent cell cycle arrest stemming from different causes. The mechanism of cellular senescence-induced cell cycle arrest is complex, involving interactions between telomere shortening, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1811bcc0eb2fbe348868c28c0aa282c2
https://doi.org/10.2174/1389450120666181217100833
https://doi.org/10.2174/1389450120666181217100833