Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jiemiao Hu"'
Autor:
Jian Wang, Wei-Lien Wang, Jiemiao Hu, Wendong Zhang, Xueqing Xia, Richard Gorlick, Shulin Li, Alexander J Lazar, Davis Ingram, Kris Mahadeo, Zhiliang Jia, Dristhi Ragoonanan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background The extracellular matrix (ECM) and cancer-associated fibroblasts (CAFs) play major roles in tumor progression, metastasis, and the poor response of many solid tumors to immunotherapy. CAF-targeted chimeric antigen receptor-T cell therapy c
Externí odkaz:
https://doaj.org/article/d9c32a3a2c1f4de797c8debfb1ea3835
Autor:
Qingnan Zhao, Jiemiao Hu, Lingyuan Kong, Shan Jiang, Xiangjun Tian, Jing Wang, Rintaro Hashizume, Zhiliang Jia, Natalie Wall Fowlkes, Jun Yan, Xueqing Xia, Sofia F. Yi, Long Hoang Dao, David Masopust, Amy B. Heimberger, Shulin Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Glioblastoma is an aggressive type of cancer with poor patient prognosis. Here, the authors show that T cells armed with an FGL2-specific scFV can induce antitumour responses mediated by tissue-resident memory T cells in the brain.
Externí odkaz:
https://doaj.org/article/a82f40cd9e5e4bbf9d2fef575b4df240
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The biological functions of WSX1, the alpha subunit of the interleukin-27 receptor, in non-immune cells are largely unknown. Here, the authors propose an IL-27-independent tumor suppressor role for WSX1 in hepatocytes, showing that WSX1 restricts tum
Externí odkaz:
https://doaj.org/article/51393f02d5054a7ea8bbacf798de9020
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Receptor-ligand binding has been analyzed at the protein level using isothermal titration calorimetry and surface plasmon resonance and at the cellular level using interaction-associated downstream gene induction/suppression. However, no currently av
Externí odkaz:
https://doaj.org/article/87cd1c2596864b3dbe8b4539514bc030
Autor:
Qing Yang, Gianpietro Dotti, Qingnan Zhao, Jiemiao Hu, Wendong Zhang, Zhongting Zhang, Xueqing Xia, Richard Gorlick, Shulin Li, Hongwei Du, Yuhui Chen, Long Dao, Fowlkes Natalie Wall, Kris Mahadeo, S Kopetz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/e02e77743cd840eb8ab54ef47dbebeb9
Autor:
Qingnan Zhao, Jiemiao Hu, Abhisek Mitra, Jeffry Cutrera, Wendong Zhang, Zhongting Zhang, Jun Yan, Xueqing Xia, Kris Michael Mahadeo, John Andrew Livingston, Richard Gorlick, Shulin Li
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Background Although accumulated evidence provides a strong scientific premise for using immune profiles to predict survival in patients with cancer, a universal immune profile across tumor types is still lacking, and how to achieve a surviva
Externí odkaz:
https://doaj.org/article/4bc1fc5e21a741b6b075c03a5520d299
Herceptin conjugates linked by EDC boost direct tumor cell death via programmed tumor cell necrosis.
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23270 (2011)
Tumor-targeted antibody therapy is one of the safest biological therapeutics for cancer patients, but it is often ineffective at inducing direct tumor cell death and is ineffective against resistant tumor cells. Currently, the antitumor efficacy of a
Externí odkaz:
https://doaj.org/article/a47b93ab8bae4aa588c16c03b6cd4e09
Publikováno v:
Neuropsychiatric Disease and Treatment. 18:2529-2541
Feng Jiang,1,2 Zhicheng Chen,1,2 Jiemiao Hu,1,2 Qianzhi Liu1,2 1Department of Neurosurgery, Ningbo Hangzhou Bay Hospital, Ningbo, 315336, Peopleâs Republic of China; 2Department of Neurosurgery, Ningbo Branch, Ren Ji Hospital, Shanghai Jiao Tong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39edbe372c2afcd6ec56d11c5ec4e325
https://doi.org/10.2147/ndt.s387487
https://doi.org/10.2147/ndt.s387487
Autor:
Shulin Li, Patrick Hwu, Mien-Chie Hung, Eugenie S. Kleinerman, Xueqing Xia, Liangfang Zhang, Chantale Bernatchez, Jiemiao Hu
Fig. S1. Gradual reduction of Rae-1 during tumor progression. Fig. S2. Induction of Rae-1 by chemotherapy in vitro but not in vivo. Fig. S3 Effector molecule perforin expression in tumors after indicated treatments. Fig. S4 Rae-1 expression is not in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905f8dce8b4601de76e82b3f62013a34
https://doi.org/10.1158/2326-6066.22538630
https://doi.org/10.1158/2326-6066.22538630
Autor:
Shulin Li, Patrick Hwu, Mien-Chie Hung, Eugenie S. Kleinerman, Xueqing Xia, Liangfang Zhang, Chantale Bernatchez, Jiemiao Hu
NKG2D-mediated immune surveillance is crucial for inhibiting tumor growth and metastases. Malignant tumor cells often downregulate NKG2D ligands to escape from immune surveillance. High-profile studies have shown that restoring NKG2D ligand expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d973dd23ea48c3842b184ffa881d6340
https://doi.org/10.1158/2326-6066.c.6548837.v1
https://doi.org/10.1158/2326-6066.c.6548837.v1