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The Traditional Chinese Medicine Compound, GRS, Alleviates Blood–Brain Barrier Dysfunction

Autor: Yang Hu, Yuanyuan Zhang, Boyang Yu, Gengshuo Guo, Jieman Wang, Fang Li, Min Li, Junping Kou

Publikováno v: Drug Design, Development and Therapy. 14:933-947

Introduction Traditional Chinese medicine (TCM) provides unique advantages for treatment of ischemic stroke, an aging-related vascular disease. Shengmai powder (GRS) is composed of three active components, specifically, ginsenoside Rb1, ruscogenin an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62e154d4450d2036f20d4c408b6e6348
https://doi.org/10.2147/dddt.s229302

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Innovative Research on Collaborative Design of Blended English Teaching in Higher Vocational Colleges Based on Digital Technology

Autor: Hua Huang, Jieman Wang

Publikováno v: Scientific Programming.

By combining the advantages of online teaching and offline teaching under digital technology, blended teaching can break the limitation of time and space, which reflects the transformation of the “student-centered” teaching paradigm. With the exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc777f19ad762225114654c62a58e5e1

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Ginsenoside Rb1 Improves Brain, Lung, and Intestinal Barrier Damage in Middle Cerebral Artery Occlusion/Reperfusion (MCAO/R) Mice Through the PPARγ Signaling Pathway

Autor: Shuaishuai Gong, zhuo Chen, Fang Li, Yuan-yuan Zhang, Junping Kou, Jieman Wang, Yuchuan Ren

BackgroundIschemic stroke causes brain inflammation and multi-organ injury, in which the peroxisome proliferator-activated receptor-gamma (PPARγ) signaling pathway plays a key role. Studies have indicated that ginsenoside Rb1 (GRb1) can protect bloo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c41805d173f15c1cc931f39782cd2505
https://doi.org/10.21203/rs.3.rs-141957/v1

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NMMHC IIA triggers neuronal autophagic cell death by promoting F-actin-dependent ATG9A trafficking in cerebral ischemia/reperfusion

Autor: Tiezheng Wang, Wentao Liu, Yuanyuan Zhang, Boyang Yu, Guangyun Wang, Yang Hu, Yan Wang, Junping Kou, Fang Li, Yang Sun, Jieman Wang

Publikováno v: Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 6, Pp 1-17 (2020)

Previous findings have shown that non-muscle myosin heavy-chain IIA (NMMHC IIA) is involved in autophagy induction triggered by starvation in D. melanogaster; however, its functional contribution to neuronal autophagy remains unclear. The aim of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd6e0a4137833e2569fd233f06a0694
http://europepmc.org/articles/PMC7280511

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Targeting blood-brain barrier leakage for visualizing , monitoring, and evaluating ischemia reperfusion injury with Rus-Tc99m Probe

Autor: Jieman Wang, Yuanyuan Zhang, Junping Kou, Zhipeng Chen, Fang Li, Yunhao Wu, Shuai-Shuai Gong, Boyang Yu, Xue-wei Pan

Cerebral ischemia-reperfusion (I/R) injury as a serious threat to human health is characterized by cerebral endothelial leakage, as a result of the damage of blood-brain barrier (BBB). It is thus quite attractive to realize real-time monitoring of BB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b2502dd7f551043be2f4876e1fcdb8c
https://doi.org/10.21203/rs.3.rs-26295/v1

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Targeting Blood-Brain Barrier Leakage for Visualizing, Monitoring, and Evaluating Ischemia Reperfusion Injury with Rus-Tc 99m Probe

Autor: Shuaishuai Gong, Jieman Wang, Zhuo Chen, Xuewei Pan, Yunhao Wu, Yuanyuan Zhang, Boyang Yu, Fang Li, Junping Kou

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::817013a74a5e9276d2ee3ece84afc29d
https://doi.org/10.2139/ssrn.3566120

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