Výsledky vyhledávání

Akademický článek

New role of endoplasmic reticulum chaperones in regulating metaplasia during tumorigenesis

Autor: Jieli Shen, Daisy F. Rangel, Dat Ha, Amy S. Lee

Publikováno v: Molecular & Cellular Oncology, Vol 4, Iss 6 (2017)

Metaplasia is emerging as a key process in tumorigenesis. We discovered that 2 essential endoplasmic reticulum (ER) chaperones, 78-kilodalton glucose-regulated protein (GRP78) and 94-kilodalton glucose-regulated protein (GRP94) have a role in metapla

Externí odkaz: https://doaj.org/article/320f76021daa4e5fa370b30ecc786b6b

Zobrazit plný text záznamu

Low-energy electron-driven observation of nanometer-sized Laves phases at alloy surfaces enabling statistical characterization with high precision and efficiency

Autor: Wenbin Guo, Songquan Wu, Liu Chengze, Yingdong Zhang, Fuzhou Han, Fusen Yuan, Jie Ren, Hengfei Gu, Muhammad Ubaid Ali, Jieli Shen, Geping Li, Lifeng Zhang

Publikováno v: Applied Nanoscience. 11:1549-1564

Alloys strengthened by nanometer-sized Laves phases have been used as structural components working in corrosive environments at high temperatures owing to the favorable physical and chemical properties of Laves phases. However, due to the small size

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97f4ef69d25beeebb418f01aa276e72d
https://doi.org/10.1007/s13204-021-01796-6

Zobrazit plný text záznamu

iFusion: Individualized Fusion Learning

Autor: Jieli Shen, Regina Y. Liu, Minge Xie

Publikováno v: Journal of the American Statistical Association. 115:1251-1267

Inferences from different data sources can often be fused together, a process referred to as “fusion learning,” to yield more powerful findings than those from individual data sources alone. Effect...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5e3e33bc353f85a5929512482d1cef6
https://doi.org/10.1080/01621459.2019.1672557

Zobrazit plný text záznamu

Nonparametric predictive distributions based on conformal prediction

Autor: Jieli Shen, Vladimir Vovk, Valery Manokhin, Minge Xie

Publikováno v: Machine Learning

This paper applies conformal prediction to derive predictive distributions that are valid under a nonparametric assumption. Namely, we introduce and explore predictive distribution functions that always satisfy a natural property of validity in terms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca64f9fff624c676b13fc0ac9dfefc9
https://doi.org/10.1007/s10994-018-5755-8

Zobrazit plný text záznamu

Prediction with confidence—A general framework for predictive inference

Autor: Jieli Shen, Minge Xie, Regina Y. Liu

Publikováno v: Journal of Statistical Planning and Inference. 195:126-140

This paper proposes a general framework for prediction in which a prediction is presented in the form of a distribution function, called predictive distribution function. This predictive distribution function is well suited for the notion of confiden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2024def6d9aabb763b8e731acbe94c26
https://doi.org/10.1016/j.jspi.2017.09.012

Zobrazit plný text záznamu

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

Autor: Amy S. Lee, Louis Dubeau, Jieli Shen, Francesco J. DeMayo, Yvonne G. Lin, Lijing Yao, John P. Lydon

Publikováno v: Oncotarget

// Jieli Shen 1 , Lijing Yao 1 , Yvonne G. Lin 2 , Francesco J. DeMayo 3 , John P. Lydon 3 , Louis Dubeau 4 , Amy S. Lee 1 1 Department of Biochemistry and Molecular Biology, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c91168953d357ce2e85e2c46759129
https://doi.org/10.18632/oncotarget.7450

Zobrazit plný text záznamu

Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis

Autor: Amy S. Lee, Atefeh Rajaei, Arjun Mehta, Wangrong Yang, Yvonne G. Lin, Jieli Shen, Francesco J. DeMayo, Hai-yun Yen, Parkash S. Gill, Eunjeong Yoo, John P. Lydon, Paulette Mhawech-Fauceglia, Ren Liu

Publikováno v: Oncogene

Rates of the most common gynecologic cancer, endometrioid adenocarcinoma (EAC), continue to rise, mirroring the global epidemic of obesity, a well-known EAC risk factor. Thus, identifying novel molecular targets to prevent and/or mitigate EAC is impe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c8bf064b9085d51e8cc7477c7f386c
https://doi.org/10.1038/onc.2015.4

Zobrazit plný text záznamu

GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice

Autor: Genyuan Zhu, Daisy F. Rangel, Parkash S. Gill, Susan Groshen, Louis Dubeau, Amy S. Lee, Dat P. Ha, Jieli Shen, Agnieszka Kobielak

Pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease in critical need of new therapeutic strategies. Here, we report that the stress-inducible 78-kDa glucose-regulated protein (GRP78/HSPA5), a key regulator of endoplasmic reticulum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a13920cf43a09f9358a5757b1c27b00c
https://europepmc.org/articles/PMC5441757/

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání