Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Jiejun, Shi"'
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The prevalence of non-alcoholic fatty liver disease (NAFLD) keeps increasing annually worldwide. Non-invasive assessment tools for evaluating the risk and severity of the disease are still limited. Insulin resistance (IR) and abdo
Externí odkaz:
https://doaj.org/article/458d955f51154bd98c16e0c5cda68092
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionCryptococcosis is the second most common invasive yeast infection in China. Pulmonary cryptococcosis (PC) is difficult to diagnose due to the lack of specific clinical features and the limitation of diagnostic techniques. Although lateral
Externí odkaz:
https://doaj.org/article/7f3a86ee079c4140b5a5c2f308ff2aea
Autor:
Jiejun Shi, Jianhua Chen, Liqing Hu, Ada Hoi Yan Ma, Haoxuan Hu, Chuwen Wang, Jiajia Huang, Qifa Song, Guoqing Qian
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Cryptococcosis is an invasive fungal disease with increased morbidity in China over the past two decades. Cryptococci can infect immunocompromised hosts as well as immunocompetent ones. In this study, we reviewed data of 71 inpatients with c
Externí odkaz:
https://doaj.org/article/1fa10062a1cf43fa95f4cc34b09095ad
Autor:
Li Yang, Xiaomin Chen, Christy Lee, Jiejun Shi, Emily B. Lawrence, Lanjing Zhang, Yumei Li, Nan Gao, Sung Yun Jung, Chad J. Creighton, Jingyi Jessica Li, Ya Cui, Sumimasa Arimura, Yunping Lei, Wei Li, Lanlan Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background Methylation of the p16 promoter resulting in epigenetic gene silencing—known as p16 epimutation—is frequently found in human colorectal cancer and is also common in normal-appearing colonic mucosa of aging individuals. Thus, t
Externí odkaz:
https://doaj.org/article/d10a6307bd33412e88191550ddc155f1
Autor:
Pranavi Koppula, Guang Lei, Yilei Zhang, Yuelong Yan, Chao Mao, Lavanya Kondiparthi, Jiejun Shi, Xiaoguang Liu, Amber Horbath, Molina Das, Wei Li, Masha V. Poyurovsky, Kellen Olszewski, Boyi Gan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
KEAP1 mutations are frequently observed in NSCLC and lead to drug resistance. Here, the authors show that KEAP1 mutations in lung cancer cells leads to FSP1 upregulation through NRF2, resulting in ferroptosis resistance and radioresistance.
Externí odkaz:
https://doaj.org/article/5fc916fe8ad34fc4b73b85133a6b2a8c
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-24 (2022)
Abstract Sestrins (Sesns), highly conserved stress-inducible metabolic proteins, are known to protect organisms against various noxious stimuli including DNA damage, oxidative stress, starvation, endoplasmic reticulum (ER) stress, and hypoxia. Sesns
Externí odkaz:
https://doaj.org/article/e5d48cd8363a42e49c629b5312d3549a
Autor:
Chuwen Wang, Danying Yan, Jiajia Huang, Naibin Yang, Jiejun Shi, Shou Pan, Gaoqiang Lin, Ying Liu, Yingying Zhang, Xueyan Bian, Qifa Song, Guoqing Qian
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundCompared with traditional diagnostic methods (TDMs), rapid diagnostic methods for infectious diseases (IDs) are urgently needed. Metagenomic next-generation sequencing (mNGS) has emerged as a promising diagnostic technology for clinical inf
Externí odkaz:
https://doaj.org/article/4bc800a7b2de48c18b039f522898c954
Autor:
Jiejun Shi, Jianfeng Xu, Yiling Elaine Chen, Jason Sheng Li, Ya Cui, Lanlan Shen, Jingyi Jessica Li, Wei Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The global pattern of the mammalian methylome is formed by changes in methylation and demethylation. Here the authors describe a metric methylation concurrence that measures the ratio of unmethylated CpGs inside the partially methylated reads and sho
Externí odkaz:
https://doaj.org/article/f3d9fde93e384899b5a04283a78052d0
Autor:
Jianfeng Xu, Jiejun Shi, Xiaodong Cui, Ya Cui, Jingyi Jessica Li, Ajay Goel, Xi Chen, Jean-Pierre Issa, Jianzhong Su, Wei Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Here, the authors introduce Cell Heterogeneity–Adjusted cLonal Methylation (CHALM) as a methylation quantification method that considers the heterogeneity of sequenced bulk cells. They apply CHALM to methylation datasets to detect differentially me
Externí odkaz:
https://doaj.org/article/b40f1c110ebc470486f84acea582f1c8
Publikováno v:
SAGE Open Medical Case Reports, Vol 9 (2021)
Cryptococcosis is a rare complication of sarcoidosis, especially when it grows in lungs. It may escape from being diagnosed because of low prevalence and non-specific radiological presentation. Hereby, we reported an unusual case of pulmonary cryptoc
Externí odkaz:
https://doaj.org/article/d34efb8d7a3341acbc6eda4efe3b2787