Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jiejie Geng"'
Autor:
Zhuan Feng, Feiyang Meng, Fei Huo, Yumeng Zhu, Yifei Qin, Yu Gui, Hai Zhang, Peng Lin, Qian He, Yong Li, Jiejie Geng, Jiao Wu
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103255- (2024)
Ferroptosis is a type of programmed cell death driven by iron-dependent lipid peroxidation. The TNF-mediated biosynthesis of glutathione has been shown to protect synovial fibroblasts from ferroptosis in the hyperplastic synovium. Ferroptosis inducti
Externí odkaz:
https://doaj.org/article/6ba34bdf33944c9097523c08c4f74c45
Autor:
Xiyu Song, Ruo Chen, Jiaxin Li, Yumeng Zhu, Jianhua Jiao, Hongjiao Liu, Zhinan Chen, Jiejie Geng
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107297- (2024)
Regulatory T (Treg) cells play a key role in maintaining immune tolerance and tissue homeostasis. However, in some disease microenvironments, Treg cells exhibit fragility, which manifests as preserved FoxP3 expression accompanied by inflammation and
Externí odkaz:
https://doaj.org/article/9b7d3264a08e493f92b296da27efd0ed
Autor:
Jiejie Geng, Xu Yang, Kun Wang, Ke Wang, Ruo Chen, Zhi-Nan Chen, Chuan Qin, Guizhen Wu, Youchun Wang, Ke Xu, Peng Du, Jiangning Liu, Shirui Chen, Tao Zhang, Xiuxuan Sun, Ting Guo, Ying Shi, Zheng Zhang, Ding Wei, Peng Lin, Qingyi Wang, Jing Yuan, Jiuxin Qu, Jin Zou, Yingxia Liu, Hongzhou Lu, Ping Zhu, Huijie Bian, Liang Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract The Omicron variants of SARS-CoV-2, primarily authenticated in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here, we systemically examined immunological and metabolic characteristics of Omicron variants infe
Externí odkaz:
https://doaj.org/article/502933fdde7444868e45a88e3af47999
Autor:
Jiao Wu, Liang Chen, Chuan Qin, Fei Huo, Xue Liang, Xu Yang, Kui Zhang, Peng Lin, Jiangning Liu, Zhuan Feng, Jiansheng Zhou, Zhuo Pei, Yatao Wang, Xiu-Xuan Sun, Ke Wang, Jiejie Geng, Zhaohui Zheng, Xianghui Fu, Man Liu, Qingyi Wang, Zheng Zhang, Huijie Bian, Ping Zhu, Zhi-Nan Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract COVID‐19 patients can develop clinical and histopathological features associated with fibrosis, but the pathogenesis of fibrosis remains poorly understood. CD147 has been identified as a universal receptor for SARS-CoV-2 and its variants,
Externí odkaz:
https://doaj.org/article/f3e46ee400804832b5eb1b08549fe995
Autor:
Jiao Wu, Zhuan Feng, Liang Chen, Yong Li, Huijie Bian, Jiejie Geng, Zhao-Hui Zheng, Xianghui Fu, Zhuo Pei, Yifei Qin, Liu Yang, Yilin Zhao, Ke Wang, Ruo Chen, Qian He, Gang Nan, Xuejun Jiang, Zhi-Nan Chen, Ping Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Expansion of synovial fibroblast is associated with rheumatoid arthritis (RA) progression, but how this expansion is regulated is still not clear. Here the authors use a mouse RA model, single cell RNA sequencing and in vitro analyses to show that in
Externí odkaz:
https://doaj.org/article/30a3aee147db4af3aa058615f826173a
Autor:
Jiejie Geng, Liang Chen, Yufeng Yuan, Ke Wang, Youchun Wang, Chuan Qin, Guizhen Wu, Ruo Chen, Zheng Zhang, Ding Wei, Peng Du, Jun Zhang, Peng Lin, Kui Zhang, Yongqiang Deng, Ke Xu, Jiangning Liu, Xiuxuan Sun, Ting Guo, Xu Yang, Jiao Wu, Jianli Jiang, Ling Li, Kun Zhang, Zhe Wang, Jing Zhang, Qingguo Yan, Hua Zhu, Zhaohui Zheng, Jinlin Miao, Xianghui Fu, Fengfan Yang, Xiaochun Chen, Hao Tang, Yang Zhang, Ying Shi, Yumeng Zhu, Zhuo Pei, Fei Huo, Xue Liang, Yatao Wang, Qingyi Wang, Wen Xie, Yirong Li, Mingyan Shi, Huijie Bian, Ping Zhu, Zhi-Nan Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract SARS-CoV-2 mutations contribute to increased viral transmissibility and immune escape, compromising the effectiveness of existing vaccines and neutralizing antibodies. An in-depth investigation on COVID-19 pathogenesis is urgently needed to
Externí odkaz:
https://doaj.org/article/d1f04b0eac0d470686ec6b84af237f4c
Autor:
Jiejie Geng, Liang Chen, Yufeng Yuan, Ruo Chen, Ke Wang, Yongqiang Deng, Peng Du, Jiangning Liu, Guizhen Wu, Youchun Wang, Ke Xu, Xiuxuan Sun, Ting Guo, Xu Yang, Jiao Wu, Jianli Jiang, Ling Li, Jun Zhang, Kui Zhang, Hua Zhu, Zhaohui Zheng, Xianghui Fu, Fengfan Yang, Xiaochun Chen, Hao Tang, Zheng Zhang, Ding Wei, Yang Zhang, Ying Shi, Yumeng Zhu, Zhuo Pei, Fei Huo, Shirui Chen, Qingyi Wang, Wen Xie, Yirong Li, Mingyan Shi, Huijie Bian, Ping Zhu, Zhi-Nan Chen
SARS-CoV-2 and its variants are raging worldwide. Unfortunately, the global vaccination is not efficient enough to attain a vaccine-based herd-immunity and yet no special and effective drug is developed to contain the spread of the disease. Previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fb47c7e68acc6bd28f1e819b8384efc
https://doi.org/10.1101/2021.05.14.444111
https://doi.org/10.1101/2021.05.14.444111
