Corticosteroid treatment ameliorates acute lung injury induced by 2009 swine origin influenza A (H1N1) virus in mice.

Autor: Chenggang Li, Penghui Yang, Yanli Zhang, Yang Sun, Wei Wang, Zhen Zou, Li Xing, Zhongwei Chen, Chong Tang, Feng Guo, Jiejie Deng, Yan Zhao, Yiwu Yan, Jun Tang, Xiliang Wang, Chengyu Jiang

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e44110 (2012)

BACKGROUND: The 2009 influenza pandemic affected people in almost all countries in the world, especially in younger age groups. During this time, the debate over whether to use corticosteroid treatment in severe influenza H1N1 infections patients res

Externí odkaz: https://doaj.org/article/547d10fac32b4b718a0e9002dd2d18fd

Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans.

Autor: Jianshe Lang, Ning Yang, Jiejie Deng, Kangtai Liu, Peng Yang, Guigen Zhang, Chengyu Jiang

Publikováno v: PLoS ONE, Vol 6, Iss 8, p e23710 (2011)

It has been reported that lactoferrin (LF) participates in the host immune response against Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) invasion by enhancing NK cell activity and stimulating neutrophil aggregation and adhesion. We furthe

Externí odkaz: https://doaj.org/article/bb204b66c65b46fd94ff709cf2751ffb

Emergence of Chinese Drug Discovery Research: Impact of Hit and Lead Identification

Autor: Caihong Zhou, Ming-Wei Wang, Jiejie Deng, Jia Wang, Yue Zhu, Yan Zhou

Publikováno v: SLAS Discovery. 20:318-329

The identification of hits and the generation of viable leads is an early and yet crucial step in drug discovery. In the West, the main players of drug discovery are pharmaceutical and biotechnology companies, while in China, academic institutions re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce227c98986edcdac601588509324dc6
https://doi.org/10.1177/1087057114561950

Highly efficient catalytic oxidation of cyclohexanol with TBHP over Cr-13X catalysts in a solvent-free system

Autor: Xinhuan Lu, Kun Li, Dan Zhou, Jiejie Deng, Qinghua Xia

Publikováno v: Journal of Molecular Catalysis A: Chemical. 387:31-37

With respect to the consideration of environment and economy, simple, inexpensive, and reusable solid catalysts have been attracting much attention. In this work, a series of non-noble transition-metal ion-exchanged zeolite catalysts have been prepar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f77caf72d754fe89c2369e5204ffee45
https://doi.org/10.1016/j.molcata.2014.02.015

Glucagon-like peptide-1 and its class B G Protein-coupled receptors: A long march to therapeutic successes

Autor: Madeleine M. Fletcher, Ming-Wei Wang, Jesper Lau, Patrick M. Sexton, Alastair J H Brown, Jung-Mo Ahn, Jiejie Deng, Jiayu Liao, Caihong Zhou, Dan Donnelly, Laurence J. Miller, Dehua Yang, Chris de Graaf, Denise Wootten

Publikováno v: de Graaf, C, Donnely, D, Wootten, D, Lau, J, Sexton, P M, Miller, L J, Ahn, J M, Liao, J, Fletcher, M M, Yang, D, Brown, A J, Zhou, C, Deng, J & Wang, M W 2016, ' Glucagon-like peptide-1 and its class B G Protein-coupled receptors: A long march to therapeutic successes. ', Pharmacological Reviews, vol. 68, no. 4, pp. 954-1013 . https://doi.org/10.1124/pr.115.011395
Pharmacological Reviews, 68(4), 954-1013. American Society for Pharmacology and Experimental Therapeutics
Pharmacological Reviews

The glucagon-like peptide (GLP)-1 receptor (GLP-1R) is a class B G protein–coupled receptor (GPCR) that mediates the action of GLP-1, a peptide hormone secreted from three major tissues in humans, enteroendocrine L cells in the distal intestine, α

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b3c58f9a679d784eb66efc8e8300c2
https://hdl.handle.net/1871.1/06e057a7-e398-4aaa-a37f-b3766c848bc8