Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jiefang Chen"'
Publikováno v:
Aggregate, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract Amyloid‐β peptide (Aβ) oligomers, characteristic symptom of Alzheimer's disease (AD), have been identified as the most neurotoxic species and significant contributors to neurodegeneration in AD. However, due to their transient and hetero
Externí odkaz:
https://doaj.org/article/5f2f20980a1741d68f87917e88339a69
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Aims: To summarize and clarify the current research status and indicate possible future directions in the field of autophagy in ischemic stroke, we performed a comprehensive and multidimensional bibliometric analysis of the literature in this field p
Externí odkaz:
https://doaj.org/article/7a44f93c24294c42b73dcf8f922e747a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/fa45dbc19a3147538fec7c9b015c17c5
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
MicroRNAs (miRNAs) participate in the regulation of various important biological processes by regulating the expression of various genes at the post-transcriptional level. Podocytopathies are a series of renal diseases in which direct or indirect dam
Externí odkaz:
https://doaj.org/article/c67ba6d9a0a74819819401dcbb7c8660
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling receptor belonging to the LDL receptor (LDLR) gene family and that is widely expressed in several tissues. LRP1 comprises a large extracellular domain (ECD
Externí odkaz:
https://doaj.org/article/c200095e23604bdb9080e36625f66185
Publikováno v:
Genes, Vol 13, Iss 5, p 796 (2022)
Renal aging has attracted increasing attention in today’s aging society, as elderly people with advanced age are more susceptible to various kidney disorders such as acute kidney injury (AKI) and chronic kidney disease (CKD). There is no clear-cut
Externí odkaz:
https://doaj.org/article/562b7ad2c63440aabb0451ddb0f6f7d3
Publikováno v:
Organic & Biomolecular Chemistry.
This review discusses the recent advances in amyloid-β oligomer-targeting agents in terms of their structural design, recognition mechanisms, and potential applications in diagnostics, therapeutics, and pathogenesis studies of Alzheimer's disease.
Autor:
Huijuan Jin, Jiefang Chen, Bo Hu, Rentang Bi, Jianzhuang Li, Zhifang Li, Shengcai Chen, Qiwei Peng
Publikováno v:
CNS Neuroscience & Therapeutics
Aims To explore the association of total bilirubin (TBIL), direct bilirubin (DBIL), and indirect bilirubin (IBIL) levels with, as well as the incremental predictive value of different bilirubin subtypes for, poor outcomes in acute ischemic stroke pat
Autor:
Jiefang Chen, Rentang Bi, Shengcai Chen, Yi Xu, Hongkai Li, Huijuan Jin, Zhifang Li, Guan-Feng Lu, Hexiang Xu, Qiwei Peng, Jianzhuang Li, Bo Hu
Publikováno v:
CNS Neuroscience & Therapeutics
Aims Morinda officinalis oligosaccharides (MOOs), a traditional Chinese medicine, have been used to treat mild and moderate depressive episodes. In this study, we investigated whether MOOs can ameliorate depressive‐like behaviors in post‐stroke d