The crosstalk between glomerular endothelial cells and podocytes controls their responses to metabolic stimuli in diabetic nephropathy

Autor: Michael Albrecht, Carsten Sticht, Tabea Wagner, Steffen A. Hettler, Carolina De La Torre, Jiedong Qiu, Norbert Gretz, Thomas Albrecht, Benito Yard, Jonathan P. Sleeman, Boyan K. Garvalov

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)

Abstract In diabetic nephropathy (DN), glomerular endothelial cells (GECs) and podocytes undergo pathological alterations, which are influenced by metabolic changes characteristic of diabetes, including hyperglycaemia (HG) and elevated methylglyoxal

Externí odkaz: https://doaj.org/article/5f11865b1b404ee3a36eeb1be0df89ad

Hypomagnesemia in persons with type 1 diabetes: associations with clinical parameters and oxidative stress

Autor: Peter R. van Dijk, F. Waanders, Jiedong Qiu, Hannah H. R. de Boer, H. van Goor, H. J. G. Bilo

Publikováno v: Therapeutic Advances in Endocrinology and Metabolism, Vol 11 (2020)

Background: Among persons with type 1 diabetes mellitus (T1DM) low concentrations of magnesium have been reported. Previous (small) studies also suggested a relation of hypomagnesemia with (poor) glycaemic control and complications. We aimed to inves

Externí odkaz: https://doaj.org/article/6f5f5955e6c648708484d7155ed96c87

The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration

Autor: Thomas Albrecht, Shiqi Zhang, Jana D. Braun, Li Xia, Angelica Rodriquez, Jiedong Qiu, Verena Peters, Claus P. Schmitt, Jacob van den Born, Stephan J. L. Bakker, Alexander Lammert, Hannes Köppel, Peter Schnuelle, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske

Publikováno v: Journal of Diabetes Research, Vol 2017 (2017)

Considering that the homozygous CNDP1 (CTG)5 genotype affords protection against diabetic nephropathy (DN) in female patients with type 2 diabetes, this study assessed if this association remains gender-specific when applying clinical inclusion crite

Externí odkaz: https://doaj.org/article/4401c6d5bd114c28a0b7fbf0e4c602fd

Flame-Retardant and Thermal Degradation Mechanism of Caged Phosphate Charring Agent with Melamine Pyrophosphate for Polypropylene

Autor: Xuejun Lai, Jiedong Qiu, Hongqiang Li, Xingrong Zeng, Shuang Tang, Ye Chen, Zhen Chen

Publikováno v: International Journal of Polymer Science, Vol 2015 (2015)

An efficient caged phosphate charring agent named PEPA was synthesized and combined with melamine pyrophosphate (MPP) to flame-retard polypropylene (PP). The effects of MPP/PEPA on the flame retardancy and thermal degradation of PP were investigated

Externí odkaz: https://doaj.org/article/bee582f311ce46e583586a58956a5a9a

Effects of Hydrochlorothiazide and Metformin on Aquaresis and Nephroprotection by a Vasopressin V2 Receptor Antagonist in ADPKD: A Randomized Crossover Trial

Autor: Bart J. Kramers, Iris W. Koorevaar, Maatje D.A. van Gastel, Harry van Goor, Kenneth R. Hallows, Hiddo L. Heerspink, Hui Li, Wouter N. Leonhard, Dorien J.M. Peters, Jiedong Qiu, Daan J. Touw, Ron T. Gansevoort, Esther Meijer

Publikováno v: Clinical journal of the American Society of Nephrology : CJASN, 17(4), 507-517. AMER SOC NEPHROLOGY
Clinical Journal of the American Society of Nephrology, 17(4), 507-517. AMER SOC NEPHROLOGY
Clin J Am Soc Nephrol

BACKGROUND AND OBJECTIVES: The vasopressin V2 receptor antagonist tolvaptan is the only drug that has been proven to be nephroprotective in autosomal dominant polycystic kidney disease (ADPKD). Tolvaptan also causes polyuria, limiting tolerability. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc76626fad9fbc5138956fcc5d7eb37e
https://research.rug.nl/en/publications/09cb50f6-b06f-4127-8f7d-39307f6c9f3f