Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jie-quan Wang"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Gout arthritis (GA) is a common and curable type of inflammatory arthritis that has been attributed to a combination of genetic, environmental and metabolic factors. Chronic deposition of monosodium urate (MSU) crystals in articular and periarticular
Externí odkaz:
https://doaj.org/article/7e41614a62b4430aaae455b931dae997
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Innate immunity activates the corresponding immune response relying on multiple pattern recognition receptors (PRRs) that includes pattern recognition receptors (PRRs), like NOD-like receptors (NLRs), RIG-I-like receptors (RLRs), and C-type lectin re
Externí odkaz:
https://doaj.org/article/af26c5c53e1d48239ef066aa64d251f7
Publikováno v:
International Journal of Biological Sciences. 19:1316-1335
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebdf415d3c4cca38263743473e382fe5
https://doi.org/10.7150/ijbs.81518
https://doi.org/10.7150/ijbs.81518
Publikováno v:
International Immunopharmacology. 117:109997
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19fedd1b671fbf10938744de5d32f94f
https://doi.org/10.1016/j.intimp.2023.109997
https://doi.org/10.1016/j.intimp.2023.109997
Publikováno v:
European Journal of Medicinal Chemistry. 156:493-509
In this study, twenty curcumin analogue hybrids as potential anticancer agents through regulation protein of TrxR were designed and synthesized. Results of anticancer activity showed that 5,7-dimethoxy-3-(3-(2-((1E, 4E)-3-oxo-5-(pyridin-2-yl)penta-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68383a50a69c2e1fa17ca97b38f5cb50
https://doi.org/10.1016/j.ejmech.2018.07.013
https://doi.org/10.1016/j.ejmech.2018.07.013
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1266-1270 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Based on our previous docking model, in order to carry out more rational drug design, totally 82 vinyl sulfonyl fluorides, including some 2-(hetero)arylethenesulfonyl fluorides and 1,3-dienylsulfonyl fluorides derivatives as potential human telomeras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3608b506c40ab8122c159b93a1296f5a
https://doi.org/10.1080/14756366.2018.1484735
https://doi.org/10.1080/14756366.2018.1484735
Autor:
Jie Quan Wang, Jing Bo Shi, Wen Jian Tang, Wei Wei Sun, Liu Zeng Chen, Li Bo, Xin Hua Liu, Hai Pin Zhou, Cheng Xiu
Publikováno v:
European Journal of Medicinal Chemistry. 138:170-181
To develop new anti-inflammatory agents with improved pharmaceutical profiles, a series of new phenyl-pyrazoline-coumarin derivatives (4a∼4m) were designed and synthesized. Compounds 4a and 4b were determined by X-ray crystallography. All of the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ceba4ae5d7cc435944e6bb8a10d7bc
https://doi.org/10.1016/j.ejmech.2017.06.044
https://doi.org/10.1016/j.ejmech.2017.06.044
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 1199-1211 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
A series of new trimethoxyphenyl-4H-chromen derivatives as telomerase inhibitors through regulation dyskerin were designed and synthesised. The anticancer activity assay in vitro showed that compound 5i 3-(4-(4-isonicotinoylpiperazin-1-yl)butoxy)-5,7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6971ec7457eea7ebb7300bf57f884e84
NLRC5 promotes cell proliferation via regulating the NF-κB signaling pathway in Rheumatoid arthritis
Autor:
Taotao Ma, Jun Li, Yao Yao, Xing Yan, Yaru Liu, Xiao-Feng Li, Hai-xia Yu, Cheng Huang, Ruo-nan Chen, Jie-quan Wang, Qingqing Xu
Publikováno v:
Molecular immunology. 91
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease and the pathogenesis remains unclear. Previous studies suggested that fibroblast-like synoviocytes (FLSs) play an important role in RA pathogenesis, including the injury of cartil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812f2199fcab3d786ed4810cbab9baa8
https://pubmed.ncbi.nlm.nih.gov/28865311
https://pubmed.ncbi.nlm.nih.gov/28865311
Autor:
Hai Ping Zhou, Li Qin, Liu Zeng Chen, Wei Xue, Xin Hua Liu, Juping Zhang, Jie Quan Wang, Wen Jian Tang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 130-138 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 130-138 (2018)
To develop novel anti-inflammatory agents, a series of new pentadienone oxime ester compounds were designed and synthesized. The structures were determined by IR, 1H NMR, 13 C NMR, and HRMS. All compounds have been screened for their anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f642ab811d1cc88b716086c89bc6eb0