Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jie-Xin Xiao"'
Publikováno v:
Steroids. 140:173-178
A novel synthetic route of producing ursodeoxycholic acid (UDCA) and obeticholic acid (OCA) was developed through multiple reactions from cheap and readily-available cholic acid. The reaction conditions of the key elimination reaction of mesylate est
Autor:
Wen-Wei Qiu, Jinhua Wang, Jia Xie, Wei Gao, Lian-Fang Yang, Jie-Xin Xiao, Jiuqing Xie, Xing Yajing, Zhengfang Yi, Wang Liting, Mingyao Liu
Publikováno v:
ACS Medicinal Chemistry Letters. 9:1105-1110
[Image: see text] Bmi-1 is overexpressed in colorectal cancer (CRC) and served as a novel therapeutic target for the treatment of CRC. A series of novel cyanoenone-modified diterpenoid analogs was synthesized and investigated for their antiproliferat
Autor:
Zhengfang Yi, Ying-Ying Wang, Jie-Xin Xiao, Wen-Wei Qiu, Xiang-Zhong Gu, Xiao-Long He, Xing Yajing
Publikováno v:
Steroids. 125
In this paper, a new and concise synthetic route of lithocholic acid (LCA) using commercially available steroid source deoxycholic acid is reported. A series of amide derivatives of LCA were also synthesized and investigated for their activity agains