Výsledky vyhledávání

In Vivo Cloning and Characterization of a New Growth Suppressor Protein TOE1 as a Direct Target Gene of Egr1

Autor: Ian de Belle, Eileen D. Adamson, Dan Mercola, Sabina Sperandio, Jie-Xin Wu

Publikováno v: Journal of Biological Chemistry. 278:14306-14312

Egr1, an immediate early transcription factor, responds to diverse stimuli and affects gene transcription to accomplish its biological effects. One important effect of Egr1 expression is to decrease the growth and tumorigenic potential of several tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c2b3dc1fb8a02e0afbc084a8032601
https://doi.org/10.1074/jbc.m210502200

Zobrazit plný text záznamu

Preneoplastic mammary tumor markers: Cripto and amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice

Autor: Bradley Spencer-Dene, Jie-Xin Wu, Eileen D. Adamson, Christina C. Niemeyer

Publikováno v: International Journal of Cancer. 81:588-591

Amphiregulin (Ar) and Cripto (Cr) are autocrine growth factors for mammary cells and both have been observed to exhibit high expression in human mammary tumors, in contrast with adjacent tissues. To investigate whether Ar and Cr play roles in the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1032a408f03389646b2d57d543e3905d
https://doi.org/10.1002/(sici)1097-0215(19990517)81:4<588::aid-ijc14>3.0.co

Zobrazit plný text záznamu

UV activates growth factor receptors via reactive oxygen intermediates

Autor: Eileen D. Adamson, Yan Fan, Jie-Xin Wu, Ruo-Pan Huang

Publikováno v: The Journal of Cell Biology

Exposure of mammalian cells to UV irradiation induces rapid and transient expression of early growth response-1 gene (Egr-1) encoding a transcription factor that plays a role in cell survival. These signals from the irradiated cell surface are likely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba37d42a7c5cd6de8b3e366dfc9d226
https://doi.org/10.1083/jcb.133.1.211

Zobrazit plný text záznamu

Inhibition of Differentiation in P19 Embryonal Carcinoma Cells by the Expression of Vectors Encoding Truncated or Antisense EGF Receptor

Autor: Eileen D. Adamson, Jie-Xin Wu

Publikováno v: Developmental Biology. 159:208-222

Murine embryonal carcinoma cells do not express detectable cell-surface epidermal growth factor receptors (EGF-R) but after 2 days of differentiation induced by retinoic acid (RA) increasingly express mRNA and protein encoded by the EGF receptor gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2bc8704001f786fffae9f109b87ada
https://doi.org/10.1006/dbio.1993.1234

Zobrazit plný text záznamu

Modulation of mouse preimplantation development by epidermal growth factor receptor antibodies, antisense RNA, and deoxyoligonucleotides

Autor: Eleanor C. Brice, Jie-Xin Wu, Lynn M. Wiley, Raffaella Muraro, Eileen D. Adamson

Publikováno v: Developmental Genetics. 14:174-184

Two-cell mouse preimplantation embryos were cultured for 48 h in four different reagents to modulate epidermal growth factor (EGF) receptor function. These were rabbit polyclonal and mouse monoclonal antibodies to EGF receptor, EGF receptor antisense

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf14c44df6a658706e8f3c7f93e181f
https://doi.org/10.1002/dvg.1020140304

Zobrazit plný text záznamu

Epidermal growth factor receptor mRNA and protein increase after the four-cell preimplantation stage in murine development

Autor: Ilana Harari, Lynn M. Wiley, Jie-Xin Wu, Eileen D. Adamson

Publikováno v: Developmental Biology. 149:247-260

Epidermal growth factor receptors (EGF-Rs) are expressed at increasing levels on mouse preimplantation embryos. Immunofluorescence assays were used to show that unfertilized eggs and 2-cell embryos have a very low level of reactivity to antimouse EGF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73482b5d866b29d4c145292299d67cdf
https://doi.org/10.1016/0012-1606(92)90282-l

Zobrazit plný text záznamu

Kinase-negative mutant epidermal growth factor receptor (EGFR) expression during embryonal stem cell differentiation favours EGFR-independent lineages

Autor: Jie-Xin Wu, Eileen D. Adamson

Publikováno v: Development (Cambridge, England). 122(10)

EGF receptors are expressed on most fetal and adult cells but their precise roles are not well known. We previously reported that, in P19 embryonal carcinoma cells, the expression of kinase-negative EGFR inhibits retinoic acid (RA)-induced differenti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c731880a080a129fed3305024d92af63
https://pubmed.ncbi.nlm.nih.gov/8898244

Zobrazit plný text záznamu

Growth Factor Receptor Changes During Development

Autor: Jie-Xin Wu, Eileen D Adamson

Publikováno v: Journal of Animal Science. 74:72

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f302567b4b9604b1aa5d271576e8549
https://doi.org/10.2527/1996.74suppl_272x

Zobrazit plný text záznamu

Akademický článek

In Vivo Cloning and Characterization of a New Growth Suppressor Protein TOE1 as a Direct Target Gene of Egr1.

Autor: de Belle, Ian, Jie-Xin Wu, Sperandio, Sabina, Mercola, Dan, Adamson, Eileen D.

Publikováno v: Journal of Biological Chemistry. 4/18/2003, Vol. 278 Issue 16, p14306. 7p. 8 Color Photographs, 23 Black and White Photographs, 5 Graphs.

Zobrazit plný text záznamu

Akademický článek

UV activates growth factor receptors via reactive oxygen...

Autor: Ruo-Pan Huang, Jie-Xin Wu

Publikováno v: Journal of Cell Biology. Apr96, Vol. 133 Issue 1, p211. 10p. 23 Black and White Photographs, 1 Chart, 3 Graphs.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání