Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jie-Bin Ou"'
Publikováno v:
Molecules, Vol 28, Iss 14, p 5598 (2023)
MSN8C, an analog of mansonone E, has been identified as a novel catalytic inhibitor of human DNA topoisomerase II that induces tumor regression and differs from VP-16(etoposide). Treatment with MSN8C showed significant antiproliferative activity agai
Externí odkaz:
https://doaj.org/article/c0863f1cca36440f8b5b54c87cada5ed
Autor:
Pei-Fen Yao, Jie-Bin Ou, Du-Chao Zhou, Honggen Wang, Zhi-Shu Huang, Hua-Ting Xie, Cheng-Cheng Liang, Shi-Liang Huang, Shuo-Bin Chen, Yan-Wen Mai
Publikováno v:
Bioorganic chemistry. 114
Novel mansonone F derivative MSN54 (9-bromo-2,3-diethylbenzo[de]chromene-7,8-dione) exhibited significant cytotoxicity against twelve human tumor cell lines in vitro, with particularly strong potency against HL-60/MX2 cell line resistant to Topo II p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7fa484813b297f89abfb342f2d55d5
https://pubmed.ncbi.nlm.nih.gov/34171594
https://pubmed.ncbi.nlm.nih.gov/34171594
Autor:
Shuo-Bin Chen, Jie-Bin Ou, Jia-Heng Tan, Ding Li, Zhi-Shu Huang, Tian-Miao Ou, Liu-Lan Shen, Lian-Quan Gu, Shi-Liang Huang, Zhi-Hong Huang, Wei-Bin Wu
Publikováno v:
European Journal of Medicinal Chemistry. 46:3339-3347
A series of mansonone F (MF) derivatives were designed and synthesized. These compounds were found to be strong inhibitors for topoisomerases, with much more significant inhibition for topoisomerase II rather than topoisomerase I. The best inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e0064cc5de0c3fa3a86ba802559d9d
https://doi.org/10.1016/j.ejmech.2011.04.059
https://doi.org/10.1016/j.ejmech.2011.04.059
Autor:
Ou, Jie-Bin1 (AUTHOR) oujieb3@mail.sysu.edu.cn, Huang, Wei-Hao2 (AUTHOR) huangwh28@mail2.sysu.edu.cn, Liu, Xing-Zi2 (AUTHOR) liuxz7@mail2.sysu.edu.cn, Dai, Guo-Yao2 (AUTHOR) daigy8@mail2.sysu.edu.cn, Wang, Lu2 (AUTHOR) wanglu79@mail2.sysu.edu.cn, Huang, Zhi-Shu2,3 (AUTHOR) ceshzs@mail.sysu.edu.cn, Huang, Shi-Liang2,3 (AUTHOR) lsshsl@mail.sysu.edu.cn
Publikováno v:
Molecules. Jul2023, Vol. 28 Issue 14, p5598. 8p.
Publikováno v:
Analytical Methods; 11/21/2017, Vol. 9 Issue 43, p6087-6091, 5p