Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jie gen Jiang"'
Autor:
Hsiang-chi Tseng, Wei Xiong, Saiaditya Badeti, Yan Yang, Minh Ma, Ting Liu, Carlos A. Ramos, Gianpietro Dotti, Luke Fritzky, Jie-gen Jiang, Qing Yi, James Guarrera, Wei-Xing Zong, Chen Liu, Dongfang Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Chimeric antigen receptor (CAR)-based therapy for the treatment of liver cancer represents a promising therapeutic strategy. Here the authors show that CD147-targeting CAR-NK or CAR-T can induce anti-tumor activity against hepatocellular carcinoma in
Externí odkaz:
https://doaj.org/article/d4aefc73f7c342c4befc39c05ef9b986
Autor:
Yan Yang, Saiaditya Badeti, Hsiang-chi Tseng, Minh Tuyet Ma, Ting Liu, Jie-Gen Jiang, Chen Liu, Dongfang Liu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 428-445 (2020)
Clinical success of chimeric antigen receptor (CAR) T cell immunotherapy requires the engineering of autologous T cells, which limits the broader implementation of CAR cell therapy. The development of allogeneic and universal cell products will signi
Externí odkaz:
https://doaj.org/article/b32c869fc35848b8a505260675717d7b
Autor:
Dongfang Liu, Saiaditya Badeti, Gianpietro Dotti, Jie-gen Jiang, He Wang, James Dermody, Patricia Soteropoulos, Deanna Streck, Raymond B. Birge, Chen Liu
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-20 (2020)
Abstract Chimeric Antigen Receptor (CAR) immunotherapy utilizes genetically-engineered immune cells that express a unique cell surface receptor that combines tumor antigen specificity with immune cell activation. In recent clinical trials, the adopti
Externí odkaz:
https://doaj.org/article/7359be6b7a24434a8270639c06e284ad
Autor:
Ruifang Zheng, Zhiwei Yin, Albert Alhatem, Derek Lyle, Bei You, Andrew S. Jiang, Dongfang Liu, Zsolt Jobbagy, Qing Wang, Seena Aisner, Jie-Gen Jiang
Publikováno v:
Cancers, Vol 12, Iss 12, p 3492 (2020)
Targeted therapy has changed the paradigm of advanced NSCLC management by improving the survival rate of patients carrying actionable gene alterations using specific inhibitors. The epidemiologic features of these alterations vary among races. Unders
Externí odkaz:
https://doaj.org/article/ed02a9d35e1a4f13a47f5d86cdbea3d1
Autor:
Luke F Fritzky, Qing Yi, Hsiang chi Tseng, Jie gen Jiang, James V. Guarrera, Wei-Xing Zong, Ting Liu, Minh Ma, Wei Xiong, Yan Yang, Dongfang Liu, Saiaditya Badeti, Gianpietro Dotti, Carlos A. Ramos, Chen Liu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Chimeric antigen receptor (CAR) therapy is a promising immunotherapeutic strategy for treating multiple refractory blood cancers, but further advances are required for solid tumor CAR therapy. One challenge is identifying a safe and effective tumor a
Autor:
Patricia Soteropoulos, Saiaditya Badeti, He Wang, Jie-Gen Jiang, Raymond B. Birge, Chen Liu, Gianpietro Dotti, Dongfang Liu, James Dermody, Deanna Streck
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-20 (2020)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Abstract Chimeric Antigen Receptor (CAR) immunotherapy utilizes genetically-engineered immune cells that express a unique cell surface receptor that combines tumor antigen specificity with immune cell activation. In recent clinical trials, the adopti
Autor:
Bei You, Deanna Streck, Jie-Gen Jiang, James Dermody, Changqing Xia, Lisa Osborne, Dibyendu Kumar, Beth A. Pletcher
Publikováno v:
Journal of Pediatric Genetics.
Wolf-Hirschhorn syndrome (WHS) is a contiguous gene deletion condition. The WHS core phenotype includes developmental delays, intellectual disabilities, seizures, and distinctive facial features. Various other comorbidities have also been reported, s
Publikováno v:
International journal of surgical pathology. 29(7)
Hamartomas are primary, benign neoplastic lesions that most commonly derive from a single variably differentiated cell lineage. Here, we report an unusual case of a cardiac hamartoma. A 62-year-old woman presented with chest pain and palpitations. Se
Publikováno v:
Cureus
Autoimmune hepatitis (AIH) and Langerhans cell histiocytosis (LCH) are two independently rare disease processes that can have similar presentations. We present a unique, complex case that required a multidisciplinary approach to ultimately diagnose a
Autor:
Dongfang Liu, Seena C. Aisner, Qing Wang, Jie Gen Jiang, Derek Lyle, Zsolt Jobbagy, Zhiwei Yin, Albert Alhatem, Bei You, Ruifang Zheng, Andrew S. Jiang
Publikováno v:
Cancers, Vol 12, Iss 3492, p 3492 (2020)
Cancers
Volume 12
Issue 12
Cancers
Volume 12
Issue 12
Targeted therapy has changed the paradigm of advanced NSCLC management by improving the survival rate of patients carrying actionable gene alterations using specific inhibitors. The epidemiologic features of these alterations vary among races. Unders