Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jie Ying Chan"'
All supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fdbafde967165affc1283240531a7d
https://doi.org/10.1158/1535-7163.22504326.v1
https://doi.org/10.1158/1535-7163.22504326.v1
Publikováno v:
Oncogene
The insulin-like growth factor (IGF) system is a well-studied growth regulatory pathway implicated in breast cancer biology. Clinical trials testing monoclonal antibodies directed against the type I IGF receptor (IGF1R) in combination with estrogen r
Publikováno v:
Hormonescancer. 9(6)
Insulin and insulin-like growth factor (IGF) signaling systems regulate breast cancer growth, progression, and metastasis. The insulin receptor substrates 1 and 2 (IRS1/2) transduce signaling from the type I IGF receptor (IGF-IR) and insulin receptor
Publikováno v:
Cancer Research. 75:P4-06
Selective estrogen receptor modulators (SERMs) such as tamoxifen have been a conventional therapy for breast cancer patients expressing estrogen receptor, representing the most common breast cancer type. The development of secondary resistance to SER
Publikováno v:
Molecular cancer therapeutics. 16(7)
Insulin receptor (InsR) and the type I insulin-like growth factor (IGF1R) are homologous receptors necessary for signal transduction by their cognate ligands insulin, IGF-I and IGF-II. IGF1R mAbs, intended to inhibit malignant phenotypic signaling, f
Publikováno v:
The Journal of Physical Chemistry C. 113:10446-10451
Nanoscale-driven design of electron emission materials can significantly increase their overall efficiency as cathodes for field-induced electron emission by taking advantage of the field enhancement effect. The refractory nature and low work functio
Publikováno v:
Cancer Research. 76:1881-1881
Selective estrogen receptor modulators (SERMs) such as tamoxifen are used to treat estrogen receptor (ER) positive breast cancers, the most common intrinsic subtype. The development of secondary resistance to SERMs is an unsolved clinical dilemma, le
Autor:
Yuzhe Yang, Dedra H. Fagan, Heather Beckwith, Aleksandra M. Ochnik, Jie Ying Chan, Xihong Zhang, Douglas Yee, Lynsey Fettig Anderson, Kelly LaPara
Publikováno v:
Molecular Cancer Research. 11:IA17-IA17
Transmembrane growth factor receptors mediate signaling through multiple intracellular pathways. In breast cancer cells, the type I insulin-like growth factor receptor (IGF1R) has been implicated in the malignant phenotype. However, clinical trials w