Výsledky vyhledávání - "Jie Y. Cavanaugh"

Role of mass spectrometry in the purification of peptides and proteins

Autor: Dorothy J. Phillips, Cecilia B. Mazza, Uwe D. Neue, Jie Y. Cavanaugh

Publikováno v: Journal of Chromatography B. 790:91-97

Experiments were carried out to evaluate the fractionation of proteins and peptides according to mass. Model mixtures were separated by either reversed-phase or ion-exchange chromatography with mass spectrometry-compatible mobile phase additives. Fra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46333bd28acbf92b31b9a07ff4a64a77
https://doi.org/10.1016/s1570-0232(03)00089-8

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At-column dilution for improved loading in preparative chromatography

Autor: Jie Y. Cavanaugh, Thomas E. Wheat, Cecilia B. Mazza, Ziling Lu, Uwe D. Neue

Publikováno v: Chromatographia. 57:S121-S127

Maximizing column loadability is an important part of preparative chromatography, since both the cost of the equipment and the cost of the operation increase with the size of the column. We have studied the parameters that determine column loadabilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b41c032c24a700e0ab75c9decab5959
https://doi.org/10.1007/bf02492093

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Differences in preparative loadability between the charged and uncharged forms of ionizable compounds

Autor: Diane M. Diehl, Thomas E. Wheat, Fang Xia, Jie Y. Cavanaugh, Cecilia B. Mazza, Uwe D. Neue, Jeffrey R. Mazzeo

Publikováno v: Journal of chromatography. A. 1030(1-2)

Ionizable compounds experience a drastic difference in preparative loadability as a function of pH. It can be shown that the preparative loadability of a compound in the ionic form is by a factor of 20 or more inferior to the loadability of the same

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65507f00dd752d09a28f52d17247d9dc
https://pubmed.ncbi.nlm.nih.gov/15043262

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