Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jie Hui Lim"'
Autor:
Conrad E Z Chan, Shirley G K Seah, De Hoe Chye, Shane Massey, Maricela Torres, Angeline P C Lim, Steven K K Wong, Jacklyn J Y Neo, Pui San Wong, Jie Hui Lim, Gary S L Loh, Dongling Wang, Jerome D Boyd-Kirkup, Siyu Guan, Dipti Thakkar, Guo Hui Teo, Kiren Purushotorman, Paul E Hutchinson, Barnaby E Young, Jenny G Low, Paul A MacAry, Hannes Hentze, Venkateshan S Prativadibhayankara, Kantharaj Ethirajulu, Jason E Comer, Chien-Te K Tseng, Alan D T Barrett, Piers J Ingram, Trevor Brasel, Brendon John Hanson
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253487 (2021)
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19, little is known about their mechanism(s) of action or effective dosing windows. We report the generation and development of SC31, a potent SARS-CoV-2 neutralizin
Externí odkaz:
https://doaj.org/article/98d0e9238a8f44f8a516de81e7cb9d0e
Autor:
Conrad En-Zuo Chan, Ching-Ging Ng, Angeline Pei-Chew Lim, Shirley Lay-Kheng Seah, De-Hoe Chye, Steven Ka-Khuen Wong, Jie-Hui Lim, Vanessa Zi-Yun Lim, Soak-Kuan Lai, Pui-San Wong, Kok-Mun Leong, Yi-Chun Liu, Richard J. Sugrue, Boon-Huan Tan
Publikováno v:
Journal of Virology. 96
A human monoclonal antibody panel (PD4, PD5, PD7, SC23, and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2-infected cells. While all five antibodies bound conformational-specific epitopes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecf7e543845d9ae3806448ce0836308
https://doi.org/10.1128/jvi.00455-22
https://doi.org/10.1128/jvi.00455-22
Autor:
Conrad En-Zuo Chan, Ching-Ging Ng, Angeline Pei-Chew Lim, Shirley Lay-Kheng Seah, De-Hoe Chye, Steven Ka-Khuen Wong, Jie-Hui Lim, Vanessa Zi-Yun Lim, Soak-Kuan Lai, Pui-San Wong, Kok-Mun Leong, Yi-Chun Liu, Richard J Sugrue, Boon-Huan Tan
A human monoclonal antibody panel (PD4, PD5, PD7, SC23 and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2- infected cells. While all five antibodies bound conformational-specific epitopes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ad3dd6e3be64a5f34854fc60afdecb
https://doi.org/10.1101/2021.12.06.471528
https://doi.org/10.1101/2021.12.06.471528
Autor:
Chien-Te K Tseng, Dipti Thakkar, Boyd-Kirkup Jerome Douglas, Trevor Brasel, Paul A. MacAry, Dong Ling Wang, Jason E. Comer, Hannes Hentze, Ingram Piers, Brendon J. Hanson, Angeline P.C. Lim, Guan Siyu, Maricela Torres, Kiren Purushotorman, Damian O’Connell, Jacklyn J.Y. Neo, Guo Hui Teo, Steven K.K. Wong, Conrad E.Z. Chan, Shirley Gek Kheng Seah, Venkateshan S. Prativadibhayankara, Paul Edward Hutchinson, De Hoe Chye, Jenny G. Low, Gary S.L. Loh, Kantharaj Ethirajulu, David C. Lye, Jie Hui Lim, Pui San Wong, Barnaby Edward Young, Alan D.T. Barrett, Shane Massey
SARS-CoV-2-neutralizing antibodies are promising therapeutics for COVID-19. However, little is known about the mechanisms of action of these antibodies or their effective dosing windows. We report the discovery and development of SC31, a potent SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::606850ac3cb09b13cecd9961dbe2c00e
https://doi.org/10.1101/2020.10.26.355107
https://doi.org/10.1101/2020.10.26.355107
Autor:
Jie Hui Lim, Pui San Wong, Steven K.K. Wong, Chien Te K. Tseng, Guan Siyu, Paul A. MacAry, Shane Massey, Shirley Gek Kheng Seah, Alan D.T. Barrett, Dipti Thakkar, Jenny G. Low, Guo Hui Teo, Kantharaj Ethirajulu, Jason E. Comer, Brendon J. Hanson, Boyd-Kirkup Jerome Douglas, Ingram Piers, Venkateshan S. Prativadibhayankara, Barnaby Edward Young, Trevor Brasel, Angeline P.C. Lim, Hannes Hentze, Maricela Torres, Dongling Wang, Kiren Purushotorman, Jacklyn J.Y. Neo, Conrad E.Z. Chan, De Hoe Chye, Paul Edward Hutchinson, Gary S.L. Loh
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253487 (2021)
PLoS ONE
PLoS ONE
Although SARS-CoV-2-neutralizing antibodies are promising therapeutics against COVID-19, little is known about their mechanism(s) of action or effective dosing windows. We report the generation and development of SC31, a potent SARS-CoV-2 neutralizin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b552438306ce977645ca8b0816814c54
https://doi.org/10.1371/journal.pone.0253487
https://doi.org/10.1371/journal.pone.0253487
Autor:
Elaine W. Lamirande, Wan-Ling Sin, Li-Fang Kuah, Yuk-Fai Lau, Jie-Hui Lim, Kanta Subbarao, Lay-Hoon Tang, Troy C. Sutton
Publikováno v:
Journal of General Virology. 98:155-165
Human infections with A/Jiangxi-Donghu/346/2013 (H10N8) virus have raised concerns about its pandemic potential. In order to develop a vaccine against this virus, the immunogenicity of its haemagglutinin protein was evaluated in mice. Using both whol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138fdb0e28e30716049d333e84c29b78
https://doi.org/10.1099/jgv.0.000683
https://doi.org/10.1099/jgv.0.000683
Publikováno v:
Vaccine. 32(42)
A prototype H7 influenza vaccine constructed based on the H7N7 outbreak in 2003 was tested for the protective efficacy against the novel H7N9 virus in a lethal murine challenge model. Serum samples from vaccinated mice showed significant neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8298cc4c40f8a1d33099428a5b7f7e90
https://pubmed.ncbi.nlm.nih.gov/25130540
https://pubmed.ncbi.nlm.nih.gov/25130540
Autor:
En-Zuo Chan, Conrad1,2 Conrad_EZ_CHAN@ncid.sg, Ching-Ging Ng1, Pei-Chew Lim, Angeline1, Lay-Kheng Seah, Shirley1, De-Hoe Chye1, Ka-Khuen Wong, Steven1, Jie-Hui Lim1, Zi-Yun Lim, Vanessa3, Soak-Kuan Lai3, Pui-San Wong1, Kok-Mun Leong1, Yi-Chun Liu1, Sugrue, Richard J.3 rjsugrue@ntu.edu.sg, Boon-Huan Tan1,3,4 tboonhua@dso.org.sg
Publikováno v:
Journal of Virology. Jul2022, Vol. 96 Issue 13, p1-27. 27p.