Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jie Hong, Hu"'
Publikováno v:
In Journal of Rock Mechanics and Geotechnical Engineering September 2024 16(9):3575-3594
Autor:
Hao Wei, Jie Hong Hu, Stoyan N. Angelov, Kate Fox, James Yan, Rachel Enstrom, Alexandra Smith, David A. Dichek
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 1 (2017)
BackgroundMarfan syndrome (MFS) is caused by mutations in the gene encoding fibrillin‐1 (FBN1); however, the mechanisms through which fibrillin‐1 deficiency causes MFS‐associated aortopathy are uncertain. Recently, attention was focused on the
Externí odkaz:
https://doaj.org/article/8bcff69578404b68bce0efd4f35d5ec6
Autor:
Francis Kim, Mark W. Majesky, Hao Wei, David A. Dichek, Jay Zhu, Ilkay Alp Yildirim, Frank V. Brozovich, Stoyan N. Angelov, Jie Hong Hu
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Humans and mice with loss-of-function variants of genes in the TGF-β (transforming growth factor beta) signaling pathway develop aortic aneurysms. These aneurysms could be caused by decreased aortic smooth muscle cell (SMC) contractile-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7dbb9008bae6f91f034af65a9c96f8
https://pubmed.ncbi.nlm.nih.gov/33853348
https://pubmed.ncbi.nlm.nih.gov/33853348
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37:2102-2113
Objective— The role of TGF-β (transforming growth factor-β) signaling in abdominal aortic aneurysm (AAA) formation is controversial. Others reported that systemic blockade of TGF-β by neutralizing antibodies accelerated AAA development in angiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a313663c75fe830a01b59fe21cb4e2d
https://doi.org/10.1161/atvbaha.117.309401
https://doi.org/10.1161/atvbaha.117.309401
Autor:
James Yan, Alexandra Smith, Kate Fox, Julie K. Allen, Thomas N. Wight, Hao Wei, Inkyung Kang, David A. Dichek, Jie Hong Hu, Stoyan N. Angelov, Liang Du, Nathan Airhart, Rachel Enstrom, Mia Jaffe
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35:2647-2656
Objective— Prenatal deletion of the type II transforming growth factor-β (TGF-β) receptor (TBRII) prevents normal vascular morphogenesis and smooth muscle cell (SMC) differentiation, causing embryonic death. The role of TBRII in adult SMC is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67c0dffbb6ed71423165b22c1acb341
https://doi.org/10.1161/atvbaha.115.306573
https://doi.org/10.1161/atvbaha.115.306573
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 37(5)
Supravalvular aortic stenosis (SVAS), a localized narrowing of the aorta just distal to the aortic valve, has been encountered sporadically for over 130 years.1,2 In 1961, Williams reported 4 patients with SVAS who shared syndromic features, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a893169ba41e2db3934bcc9c0b3515
https://pubmed.ncbi.nlm.nih.gov/28254817
https://pubmed.ncbi.nlm.nih.gov/28254817
Autor:
Alexandra Smith, Stoyan N. Angelov, James Yan, Rachel Enstrom, David A. Dichek, Hao Wei, Jie Hong Hu, Kate Fox
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Marfan syndrome ( MFS ) is caused by mutations in the gene encoding fibrillin‐1 ( FBN 1 ); however, the mechanisms through which fibrillin‐1 deficiency causes MFS ‐associated aortopathy are uncertain. Recently, attention was focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88ad78bdbd000949ae30423bbfa46b9
https://pubmed.ncbi.nlm.nih.gov/28119286
https://pubmed.ncbi.nlm.nih.gov/28119286
Autor:
Michal Kremen, Isaac Emery, Stephen A. Ramsey, David A. Dichek, Stephen D. Farris, Elizabeth S. Gold, Ranjini M. Krishnan, Helén L. Dichek, Talyn Chu, Jie Hong Hu, Liang Du
Publikováno v:
Journal of Biological Chemistry. 286:22665-22677
Data from clinical studies, cell culture, and animal models implicate the urokinase plasminogen activator (uPA)/uPA receptor (uPAR)/plasminogen system in the development of atherosclerosis and aneurysms. However, the mechanisms through which uPA/uPAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008efea7d815eec15f8f1c73b90e8009
https://doi.org/10.1074/jbc.m110.202135
https://doi.org/10.1074/jbc.m110.202135
Autor:
Jie Hong Hu, Helén L. Dichek, Liang Du, Stephen D. Farris, Katherine I. Slezicki, Talyn Chu, Isaac Emery, David A. Dichek, Michal Kremen, Ranjini M. Krishnan
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1737-1744
Objective— Enhanced plasminogen activation, mediated by overexpression of urokinase-type plasminogen activator (uPA), accelerates atherosclerosis in apolipoprotein E–null mice. However, the mechanisms through which uPA acts remain unclear. In add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61267225389de06e7ee6d4c1d513954d
https://doi.org/10.1161/atvbaha.109.195529
https://doi.org/10.1161/atvbaha.109.195529
Autor:
Caroline J. Pennington, Casilde Sesti, Liang Du, April Stempien-Otero, Dylan R. Edwards, Michael R. Preusch, Madeline Nieves-Cintrón, David A. Dichek, Andrew D. Frutkin, Helén L. Dichek, Daniel Minter, Mia Jaffe, Goro Otsuka, Julien C. Marie, Jie Hong Hu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:1251-1257
Objective—Impairment of transforming growth factor (TGF)-β1 signaling accelerates atherosclerosis in experimental mice. However, it is uncertain whether increased TGF-β1 expression would retard atherosclerosis. The role of TGF-β1 in aneurysm for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc87cc5a1138042453a131a3dfad85d
https://doi.org/10.1161/atvbaha.109.186593
https://doi.org/10.1161/atvbaha.109.186593