Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jichun Gu"'
Autor:
Siyu Zhou, Baian Tao, Yujie Guo, Jichun Gu, Hengchao Li, Caifeng Zou, Sichong Tang, Shuheng Jiang, Deliang Fu, Ji Li
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Deciphering the role of plasma proteins in pancreatic cancer (PC) susceptibility can aid in identifying novel targets for diagnosis and treatment. Methods We examined the relationship between genetically determined levels of plasm
Externí odkaz:
https://doaj.org/article/1f1a3065927f45bcb1b82c0c30ef2ea4
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Abstract Background Sodium glucose transporters (SGLTs) play vital roles in glucose uptake in many solid cancers, including pancreatic cancer (PC). However, their expression profile in pancreatic cancer and correlation with prognosis are not clear. T
Externí odkaz:
https://doaj.org/article/48933a9120544fa58eb2668f0578b9eb
Autor:
Lei Kong, Jiali Du, Jichun Gu, Junyuan Deng, Yujie Guo, Baian Tao, Chen Jin, Deliang Fu, Ji Li
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
PurposeGemcitabine (GEM) is the first-line chemotherapeutic drug for pancreatic cancer treatment in clinical practice. However, many reasons can reduce the efficacy of GEM, among which the high expression of ATP-binding cassette (ABC) transporters is
Externí odkaz:
https://doaj.org/article/483e1d9c7ca44124ade12d00d01a7890
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Increased insulin level (or “hyperinsulinemia”) is a common phenomenon in pancreatic ductal adenocarcinoma (PDA) patients and signals poor clinical outcomes. Insulin is safe in low PDA risk population, while insulin significantly promotes PDA ris
Externí odkaz:
https://doaj.org/article/33132f18981b45f6a089da4f7cf76fca
Publikováno v:
Cancer Medicine, Vol 9, Iss 15, Pp 5535-5545 (2020)
Abstract Pancreatic cancer (PC) is a highly lethal tumor with controversial high glucose uptake and hypomicrovascularity, and the hypomicrovasculature, which is considered to have poor perfusion, blocks the delivery of drugs to tumors. The preferenti
Externí odkaz:
https://doaj.org/article/ae644067eba64cfdafa36abd3d26105d
Autor:
Jichun Gu, Jiali Du, Zhibo Xie, Caifeng Zou, Hang He, Hengchao Li, Lie Yao, Sijie Hao, Deliang Fu, Chen Jin, Ji Li
Publikováno v:
Surgery in Practice and Science, Vol 1, Iss , Pp 100009- (2020)
Background: : Postoperative pancreatic fistula (POPF) is one of the most common complications and the leading cause of morbidity and mortality after pancreatic operation with pancreatojejunostomy (PJ). Many strategies have been used to prevent the in
Externí odkaz:
https://doaj.org/article/d776935647c54cf4be420cf2464b1797
Autor:
Jichun Gu, Yujie Guo, Jiali Du, Lei Kong, Junyuan Deng, Baian Tao, Hengchao Li, Chen Jin, Deliang Fu, Ji Li
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5434
(1) Background: Recently, cell division cycle associated 8 (CDCA8) was found to be overexpressed in pancreatic ductal adenocarcinoma (PDAC). Here, we aimed to explore the specific mechanism of action of CDCA8 in PDAC progression. (2) Methods: All hum
Publikováno v:
Cancer Management and Research.
Junyuan Deng, Yujie Guo, Jichun Gu, Jiali Du, Lei Kong, Boan Tao, Ji Li, Deliang Fu Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Fudan University, Shanghai, Peopleâs Republic of ChinaCorrespondence: Ji Li, De
Publikováno v:
The Journal of Pathology
Apical microvilli of polarized epithelial cells govern the absorption of metabolites and the transport of fluid in tissues. Previously, we reported that tall and dense basal microvilli present on the endothelial cells of pancreatic cancers, a lethal
Autor:
Yang Di, Jia Song, Deliang Fu, Shangli Cai, Ji Li, Shiqing Chen, Jichun Gu, Yongjian Jiang, Lie Yao, Zhou Yuan, Hang He, Hengchao Li, Chen Jin, Jiajun Lu
Publikováno v:
Journal of Cancer
Objective: Pancreatic cancer (PC) is a malignant tumor with limited therapeutic choices and extremely poor prognosis. Personalized therapy based on gene alternations is a promising choice. Considering tumor heterogeneity, the practice of ctDNA analys