Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jichuan Shan"'
Autor:
Hedi Zhao, Vanessa Moarbes, Véronique Gaudreault, Jichuan Shan, Haya Aldossary, Louis Cyr, Elizabeth D. Fixman
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Sex differences in asthma prevalence are well-documented but poorly understood. Murine models have contributed to our understanding of mechanisms that could regulate this sex disparity, though the majority of these studies have examined responses pre
Externí odkaz:
https://doaj.org/article/0f69a4fbb47a42adafe1ab5db0e45d96
Autor:
Vanessa Moarbes, Véronique Gaudreault, Rami Karkout, Lydia Labrie, Hedi Zhao, Jichuan Shan, Elizabeth D. Fixman
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950).
Recent interest has focused on innate-type cytokines as promoters of type 2 immunity and targets for drug development in asthma. IL-33 induces production of IL-4 and/or IL-13, which is associated with STAT6-dependent responses in innate cells, includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a441e0d8021473d1cb41ef843eb5f6
https://pubmed.ncbi.nlm.nih.gov/36241369
https://pubmed.ncbi.nlm.nih.gov/36241369
Autor:
Elizabeth D. Fixman, Véronique Gaudreault, Soojin Lee, Mark Bazett, Jichuan Shan, Haya Aldossary
Publikováno v:
European Journal of Immunology. 49:157-169
Type 2 immunity in the lung is promoted through the release of innate cytokines, including TSLP, from lung structural cells. These cytokines drive Type 2 immunity in part through upregulation of OX40L on dendritic cells (DCs). DCs expressing OX40L ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ea748ec6f375e3d30de3b04d006843
https://doi.org/10.1002/eji.201847534
https://doi.org/10.1002/eji.201847534
Autor:
Louis Cyr, Hedi Zhao, Vanessa Moarbes, Elizabeth D. Fixman, Jichuan Shan, Véronique Gaudreault, Haya Aldossary
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Sex differences in asthma prevalence are well-documented but poorly understood. Murine models have contributed to our understanding of mechanisms that could regulate this sex disparity, though the majority of these studies have examined responses pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b25a1efedacf010d18aed3124f912a
http://europepmc.org/articles/PMC6504808
http://europepmc.org/articles/PMC6504808
Autor:
Elizabeth D. Fixman, Soojin Lee, Bharat T. Srinivasa, Brian J. Ward, Li Xing, Louis Cyr, Katherine H. Restori, Jichuan Shan
Publikováno v:
Journal of Leukocyte Biology. 101:519-529
Respiratory syncytial virus (RSV)-related hospitalization during infancy is strongly associated with the subsequent development of asthma. Early life RSV infection results in a Th2-biased immune response, which is also typical of asthma. Murine model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a260c6f733ebc8f61802f897d1b3edb
https://doi.org/10.1189/jlb.4a0215-062rr
https://doi.org/10.1189/jlb.4a0215-062rr
Publikováno v:
Mucosal Immunology. 8:1248-1261
We sought to modulate mucosal immune responses using neonatal vaccination to avert the development of allergic airways disease (AAD). Pulmonary pathology in AAD is driven by T helper (TH)2 cytokines, in particular interleukin (IL)4 and IL13, the expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794ef30462d152749fe28835aefefdc0
https://doi.org/10.1038/mi.2015.15
https://doi.org/10.1038/mi.2015.15
Autor:
Nakada, Emily M.1, Jichuan Shan1, Kinyanjui, Margaret W.1, Fixman, Elizabeth D.1 elizabeth.fixman@mcgill.ca
Publikováno v:
Respiratory Research. 2014, Vol. 15 Issue 8, p1-14. 14p. 6 Graphs.
Autor:
Sabah N. A. Hussain, Kathy Levesque, Karuthapillai Govindaraju, William S. Powell, Jichuan Shan, David H. Eidelman
Publikováno v:
Nitric Oxide. 18:184-194
To investigate peroxidase induced 3'-nitrotyrosine (3NT) formation, neutrophil derived myeloperoxidase (MPO) (0.025 microM) was directly administered to A549 epithelial cells with or without H(2)O(2) (150 microM). Little evidence of 3NT was found. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad6fd4f770612c96cce62a9a34142e3
https://doi.org/10.1016/j.niox.2008.01.004
https://doi.org/10.1016/j.niox.2008.01.004
Autor:
Michelle Robinson, Julio F. Bernardes, Marc A. Tewfik, Jichuan Shan, Saul Frenkiel, David H. Eidelman
Publikováno v:
American Journal of Rhinology. 17:269-274
Background The presence of nitric oxide (NO) in high concentrations has been described in the nasal mucosa of patients with untreated allergic rhinitis. We sought to examine the role of exogenous, as well as endogenous, NO in the production of collag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5036431221a3938ffce6b36c71af3994
https://doi.org/10.1177/194589240301700504
https://doi.org/10.1177/194589240301700504
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 190(8)
The Th2 cytokine IL-13 regulates several aspects of the asthmatic phenotype, including airway inflammation, airway hyperresponsiveness, and mucus production. The Th17 cytokine IL-17A is also implicated in asthma and has been shown to both positively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcbf56cee91c7fe494300539ffc4d97
https://pubmed.ncbi.nlm.nih.gov/23509346
https://pubmed.ncbi.nlm.nih.gov/23509346