Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jichao Qin"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract Chemotherapy is a crucial treatment for colorectal tumors. However, its efficacy is restricted by chemoresistance. Recently, Golgi dispersal has been suggested to be a potential response to chemotherapy, particularly to drugs that induce DNA
Externí odkaz:
https://doaj.org/article/02e8417970c24de8a3dc5f63fa2f0ee2
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-12 (2022)
Abstract Uneven oxygen supply in solid tumors leads to hypoxic and normoxic regions. Hypoxic cells exhibit increased secretion of lactate, which creates an acidic tumor microenvironment (TME). This acidic TME is positively associated with tumor metas
Externí odkaz:
https://doaj.org/article/2f0785ab157d4eb6880b1d931835201e
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe purpose of this study is to construct a novel and practical nomogram and risk stratification system to accurately predict cancer-specific survival (CSS) of early-onset locally advanced rectal cancer (EO-LARC) patients.MethodsA total of
Externí odkaz:
https://doaj.org/article/0fae8104e26447978e597b3c7bd96409
Publikováno v:
Gastroenterology Research and Practice, Vol 2021 (2021)
Background. The optimal timing of temporary ileostomy closure with respect to the time of adjuvant chemotherapy following sphincter-saving surgery for rectal cancer remains unclear. The aim of this study is to investigate the clinical and oncological
Externí odkaz:
https://doaj.org/article/cbcc829f871544568ca442075020a68f
Autor:
Jie Shen, Beibei Cao, Yatao Wang, Aitang Xiao, Jichao Qin, Jianhong Wu, Qun Yan, Yuanlong Hu, Chuanyong Yang, Zhixin Cao, Junbo Hu, Ping Yin, Daxing Xie, Jianping Gong
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Although radical gastrectomy with D2 lymph node dissection has become the standard surgical approach for locally advanced gastric cancer, patients still have a poor prognosis after operation. Previously, we proposed laparoscopic d
Externí odkaz:
https://doaj.org/article/0934a7b0b54240aabd48cef408e6fb24
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125625 (2015)
Chemotherapy resistance observed in patients with colorectal cancer (CRC) may be related to the presence of cancer stem cells (CSCs), but the underlying mechanism(s) remain unclear. Carcinoma-associated fibroblasts (CAFs) are intimately involved in t
Externí odkaz:
https://doaj.org/article/9cb306a17cea4a439d73ece523f704a6
Autor:
Hong Yan, Xin Chen, Qiuping Zhang, Jichao Qin, Hangwen Li, Can Liu, Tammy Calhoun-Davis, Luis Della Coletta, Jim Klostergaard, Izabela Fokt, Stanislaw Skora, Waldemar Priebe, Yongyi Bi, Dean G Tang
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24397 (2011)
Cancer stem cells (CSCs) possess high tumor-initiating capacity and have been reported to be resistant to therapeutics. Vice versa, therapy-resistant cancer cells seem to manifest CSC phenotypes and properties. It has been generally assumed that drug
Externí odkaz:
https://doaj.org/article/c7e5d31bf56b45a887f8e349390ab53d
Autor:
He-Ge Chen, Wen-Jun Han, Mi Deng, Jichao Qin, Dan Yuan, Jin-Ping Liu, Ling Xiao, Lili Gong, Songping Liang, Jian Zhang, Yun Liu, David Wan-Cheng Li
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7019 (2009)
Protein phosphatases-2A (PP-2A) is a major serine/threonine phosphatase and accounts for more than 50% serine/threonine phosphatase activity in eukaryotes. The holoenzyme of PP-2A consists of the scaffold A subunit, the catalytic C subunit and the re
Externí odkaz:
https://doaj.org/article/c32429e7e4a24cf28c23fa725b9d13e1
Autor:
Yangkun Li, Qilin Li, Lei Mu, Yibing Hu, Chang Yan, Hui Zhao, Yulong Mi, Xiaolan Li, Deding Tao, Jichao Qin
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 7, p2748-2762, 15p
Publikováno v:
European Journal of Surgical Oncology. 49:433-439
Due to the difficult evaluation of the risk of anastomotic leakage (AL) after rectal cancer resection, the decision to perform a temporary ileostomy is not easily distinguishable. The aim of the present study was to develop an artificial intelligence