Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Jichao, He"'
1
Akademický článek
Operational strategies to alleviate thermal impacts of the large-scale borehole heat exchanger array in Beijing Daxing Airport
Autor: Yaqian Ren, Yanlong Kong, Yonghui Huang, Shu Bie, Zhonghe Pang, Jichao He, Wei Yi, Bin He, Jiyang Wang
Publikováno v: Geothermal Energy, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Large-scale ground source heat pump (GSHP) systems are increasingly used for space heating and cooling. In comparison with smaller ones, large GSHP systems are often coupled with much more borehole heat exchangers (BHEs). Because of the inte
Externí odkaz: https://doaj.org/article/0341cfb5b61c4f4e8bba117531354772
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2
Akademický článek
A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy
Autor: Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang, Bob van de Water
Publikováno v: Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Abstract Background The effective treatment of triple-negative breast cancer (TNBC) remains a profound clinical challenge. Despite frequent epidermal growth factor receptor (EGFR) overexpression and reliance on downstream signalling pathways in TNBC,
Externí odkaz: https://doaj.org/article/d7a9858eb35e4f8bbbf909c779d15779
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3
MPS-Net: Learning to recover surface normal for multispectral photometric stereo
Autor: Feng Gao, Yakun Ju, Xinghui Dong, Junyu Dong, Lin Qi, Jichao He
Publikováno v: Neurocomputing. 375:62-70
Multispectral Photometric Stereo (MPS) estimates per-pixel surface normals from one single image captured under three colored (red, green and blue) light sources. Unlike traditional Photometric Stereo, MPS can therefore be used in dynamic scenes for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12ba7cd6e9d6ef146e97701cc94e4e75
https://doi.org/10.1016/j.neucom.2019.09.084
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4
Multi-targeted kinase inhibition alleviates mTOR inhibitor resistance in triple-negative breast cancer
Autor: John A. Foekens, Gerard J. P. van Westen, Jichao He, Bob van de Water, Vera E. van der Noord, John W.M. Martens, Ronan P. McLaughlin, Yinghui Zhang
Publikováno v: Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 178(2), 263-274. Springer New York
Breast Cancer Research and Treatment, 178(2), 263-274
Purpose Owing to its genetic heterogeneity and acquired resistance, triple-negative breast cancer (TNBC) is not responsive to single-targeted therapy, causing disproportional cancer-related death worldwide. Combined targeted therapy strategies to blo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0caa5eb313c946bd778de6baf1b4ee
https://doi.org/10.1007/s10549-019-05380-z
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5
Optimization of the Global Largest Ground Source Heat Pump System
Autor: Yaqian Ren, Yanlong Kong, Jichao He, Yonghui Huang, Haibing Shao, Zhonghe Pang, Bin He, Jiyang Wang, Wei Yi
Publikováno v: SSRN Electronic Journal.
Large-scale ground source heat pump systems (GSHPs) are increasingly used for space heating and cooling. In comparison to small-scale GSHPs, large GSHPs are often coupled with hundreds of borehole heat exchangers (BHE), which are more susceptible to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7dfa346f9e8d3bf19aa39682fb64922
https://doi.org/10.2139/ssrn.3946175
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6
Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression
Autor: Marcel Smid, Bob van de Water, Sander Canisius, John A. Foekens, Ronan P. McLaughlin, John W.M. Martens, Yinghui Zhang, Lambert van der Beek, Lodewyk F. A. Wessels, Jichao He
Publikováno v: Oncogene
Oncogene, 39(20), 4118-4131
Oncogene, 39(20), 4118-4131. Nature Publishing Group
The genetically heterogeneous triple-negative breast cancer (TNBC) continues to be an intractable disease, due to lack of effective targeted therapies. Gene amplification is a major event in tumorigenesis. Genes with amplification-dependent expressio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cadcc244ee05c50a4711058e9e7692
https://hdl.handle.net/1887/137155
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7
FRET biosensor-based kinase inhibitor screen for ERK and AKT activity reveals differential kinase dependencies for proliferation in TNBC cells
Autor: Bob van de Water, Jichao He, Hans de Bont, Steven Wink, Yinghui Zhang, Sylvia E. Le Dévédec
Publikováno v: Biochemical Pharmacology, 169, 113640
Enhanced expression and activity of protein kinases are critical in tumor cell proliferation and cancer progression. These various cancer-related kinases form intricate interdependent signaling networks. Evaluation of the effect of various kinase inh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44f41bd58ac5b930328fa313dd3161f
https://doi.org/10.1016/j.bcp.2019.113640
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8
A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy
Autor: Yinghui Zhang, Marcel Smid, Jichao He, Ronan P. McLaughlin, Vera E. van der Noord, John W.M. Martens, Jevin Redel, Bob van de Water, John A. Foekens
Publikováno v: Breast Cancer Research : BCR
Breast Cancer Research, 21, 77
Breast Cancer Research
Breast Cancer Research, Vol 21, Iss 1, Pp 1-15 (2019)
Breast Cancer Research, 21:77. BioMed Central Ltd.
Background The effective treatment of triple-negative breast cancer (TNBC) remains a profound clinical challenge. Despite frequent epidermal growth factor receptor (EGFR) overexpression and reliance on downstream signalling pathways in TNBC, resistan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cadad1eae435379a4058f43e2b53bf
https://pubmed.ncbi.nlm.nih.gov/31262335
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9
IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer
Autor: Lynn Wester, Marjo de Graauw, Tamar Geiger, John W.M. Martens, Yinghui Zhang, Chantal Pont, Bob van de Water, Jean A. Helmijr, Maurice P.H.M. Jansen, Maxime P. Look, Marja Moerkens, Caroline H M van Deurzen, John H. N. Meerman, Els M.J.J. Berns, Erik H.J. Danen, Mieke M. Timmermans, Ram Siddappa, Jichao He
Publikováno v: Oncogene, 37(14), 1869-1884. Nature Publishing Group
Antiestrogen resistance in estrogen receptor positive (ER+) breast cancer is associated with increased expression and activity of insulin-like growth factor 1 receptor (IGF1R). Here, a kinome siRNA screen has identified 10 regulators of IGF1R-mediate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474be77ac75a490aa422f25e9f8034a7
https://hdl.handle.net/1887/3202823
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10
Nonparametric Tree-Based Predictive Modeling of Storm Outages on an Electric Distribution Network
Autor: Jichao, He, David W, Wanik, Brian M, Hartman, Emmanouil N, Anagnostou, Marina, Astitha, Maria E B, Frediani
Publikováno v: Risk analysis : an official publication of the Society for Risk Analysis. 37(3)
This article compares two nonparametric tree-based models, quantile regression forests (QRF) and Bayesian additive regression trees (BART), for predicting storm outages on an electric distribution network in Connecticut, USA. We evaluated point estim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fbea10e6d9a5bc009d777a58c79b679
https://pubmed.ncbi.nlm.nih.gov/28418593
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