Zobrazeno 1 - 1
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pro vyhledávání: '"Jibran Nehal Syed"'
Autor:
Abdalla Ahmed, Jibran Nehal Syed, Lijun Chi, Yaxu Wang, Carmina Perez-Romero, Dorothy Lee, Etri Kocaqi, Amalia Caballero, Jielin Yang, Quetzalcoatl Escalante-Covarrubias, Akihiko Ishimura, Takeshi Suzuki, Lorena Aguilar-Arnal, Gerard Bryan Gonzales, Kyoung-Han Kim, Paul Delgado-Olguín
Publikováno v:
Nature Cardiovascular Research. 2:174-191
Cardiac metabolism is deranged in heart failure, but underlying mechanisms remain unclear. Here, we show that lysine demethylase 8 (Kdm8) maintains an active mitochondrial gene network by repressing Tbx15, thus preventing dilated cardiomyopathy leadi