Výsledky vyhledávání - "Jibran Ja Wali"

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

Autor: Thomas W.H. Kay, Lut Overbergh, Dieter Rondas, Chantal Mathieu, Stacey Fynch, Jibran Ja Wali, Helen E. Thomas, Andreas Strasser, Mark D. McKenzie, Esteban Nicolas Gurzov, Yuxing Zhao, Shizuo Akira, Lorraine Elkerbout

Publikováno v: Cell death & disease, 5
Cell Death & Disease

Apoptosis of pancreatic beta cells is a feature of type 2 diabetes and its prevention may have therapeutic benefit. High glucose concentrations induce apoptosis of islet cells, and this requires the proapoptotic Bcl-2 homology domain 3 (BH3)-only pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de89d9a548d7de59388b8a4a9e4baac
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260216

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