Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jibran A Wali"'
Autor:
Jibran A. Wali, Duan Ni, Harrison J. W. Facey, Tim Dodgson, Tamara J. Pulpitel, Alistair M. Senior, David Raubenheimer, Laurence Macia, Stephen J. Simpson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The metabolic effects of sugars and fat lie at the heart of the “carbohydrate vs fat” debate on the global obesity epidemic. Here, we use nutritional geometry to systematically investigate the interaction between dietary fat and the majo
Externí odkaz:
https://doaj.org/article/f5a90d3a385d45ddb77b2968864670c5
Autor:
Jian Tan, Duan Ni, Jemma Taitz, Gabriela Veronica Pinget, Mark Read, Alistair Senior, Jibran Abdul Wali, Reem Elnour, Erin Shanahan, Huiling Wu, Steven J. Chadban, Ralph Nanan, Nicholas Jonathan Cole King, Georges Emile Grau, Stephen J. Simpson, Laurence Macia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Secretory IgA plays vital roles interfacing between the host immune system and the resident microbiota at the mucosal surface. Here the authors explore the effect of dietary protein on the production of secretory IgA, driven by the production of extr
Externí odkaz:
https://doaj.org/article/1a558a672c5147d9bc844ff084a46355
Autor:
Jiabao Yan, Cuiru Ren, Yunlong Dong, Jibran A. Wali, Hongjie Song, Ying Zhang, Hengrui Zhang, Guangning Kou, David Raubenheimer, Zhenwei Cui
Publikováno v:
Nutrients, Vol 15, Iss 1, p 251 (2023)
Obesity is a serious public health issue worldwide. Growing evidence demonstrates the efficacy of the ketogenic diet (KD) for weight loss, but there may be some adverse side effects such as dyslipidemia and hepatic steatosis. Aerobic exercise is a wi
Externí odkaz:
https://doaj.org/article/f4ce853ce8cd4524ad463ab441ac9726
Autor:
Jian Tan, Duan Ni, Jibran Abdul Wali, Darren Anthony Cox, Gabriela Veronica Pinget, Jemma Taitz, Claire Immediato Daïen, Alistair Senior, Mark Norman Read, Stephen James Simpson, Nicholas Jonathan Cole King, Laurence Macia
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102835- (2021)
Summary: While diet modulates immunity, its impact on B cell ontogeny remains unclear. Using mixture modeling, a large-scale isocaloric dietary cohort mouse study identified carbohydrate as a major driver of B cell development and function. Increasin
Externí odkaz:
https://doaj.org/article/7a5e95ba684f4b70858620e02385dd8d
Autor:
Juliano Morimoto, Alistair Senior, Kate Ruiz, Jibran A Wali, Tamara Pulpitel, Samantha M Solon-Biet, Victoria C Cogger, David Raubenheimer, David G Le Couteur, Stephen J Simpson, Joerg Eberhard
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0212796 (2019)
While there is a burgeoning interest in the effects of nutrition on systemic inflammatory diseases, how dietary macronutrient balance impacts local chronic inflammatory diseases in the mouth has been largely overlooked. Here, we used the Geometric Fr
Externí odkaz:
https://doaj.org/article/3be45fd96d7e483fb5cd8fc45277fcfe
Autor:
Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali, Tamara Pulpitel, Ximonie Clark, David Raubenheimer, Alistair M. Senior, David A. Sinclair, Gregory J. Cooney, Rafael de Cabo, Victoria C. Cogger, Stephen J. Simpson, David G. Le Couteur
Publikováno v:
Cell Reports, Vol 25, Iss 8, Pp 2234-2243.e6 (2018)
Summary: Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether they are beneficial for brain health. We compared hippoca
Externí odkaz:
https://doaj.org/article/01bfc1c1dff647aeb3faeae44f8706aa
Publikováno v:
Biology, Vol 10, Iss 4, p 336 (2021)
Obesity caused by the overconsumption of calories has increased to epidemic proportions. Insulin resistance is often associated with an increased adiposity and is a precipitating factor in the development of cardiovascular disease, type 2 diabetes, a
Externí odkaz:
https://doaj.org/article/c96ce5319f674b04b3a4f150c75d11bd
Autor:
Jibran A. Wali, Natalia Jarzebska, David Raubenheimer, Stephen J. Simpson, Roman N. Rodionov, John F. O’Sullivan
Publikováno v:
Nutrients, Vol 12, Iss 5, p 1505 (2020)
The majority of the epidemiological evidence over the past few decades has linked high intake of fats, especially saturated fats, to increased risk of diabetes and cardiovascular disease. However, findings of some recent studies (e.g., the PURE study
Externí odkaz:
https://doaj.org/article/d62afd7d69934c6abc2fabdf49edfb22
Autor:
Glen P Lockwood, Josephine M. Forbes, Belinda Yau, Alistair M. Senior, Amanda E. Brandon, Samantha M. Solon-Biet, David Raubenheimer, Rosilene V Ribeiro, John F. O'Sullivan, David G. Le Couteur, Alison W S Luk, Kim S. Bell-Anderson, Gregory J. Cooney, Annabelle J. Milner, Andrew J. Holmes, Harrison J. W. Facey, Mitchell A. Sullivan, Jibran A Wali, Victoria C. Cogger, Stephen J. Simpson, Melkam A. Kebede, Tamara Pulpitel, Tim Dodgson, Laurence Macia, Yen Chin Koay, Devin Wahl
Publikováno v:
Nature Metabolism. 3:810-828
Reduced protein intake, through dilution with carbohydrate, extends lifespan and improves mid-life metabolic health in animal models. However, with transition to industrialised food systems, reduced dietary protein is associated with poor health outc
Publikováno v:
Cells, Vol 2, Iss 2, Pp 266-283 (2013)
Pancreatic beta-cell apoptosis is an important feature of islets in type 2 diabetes. Apoptosis can occur through two major pathways, the extrinsic or death receptor mediated pathway, and the intrinsic or Bcl-2-regulated pathway. Hyperglycaemia, hyper
Externí odkaz:
https://doaj.org/article/74e719a366404598acdd509b9860f9c5