Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Jiazuan, Ni"'
Autor:
Bingyu Ren, Jiaxin Situ, Xuelian Huang, Qiulong Tan, Shifeng Xiao, Nan Li, Jing Tian, Xiubo Du, Jiazuan Ni, Qiong Liu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract Lower selenium levels are observed in Alzheimer’s disease (AD) brains, while supplementation shows multiple benefits. Selenoprotein W (SELENOW) is sensitive to selenium changes and binds to tau, reducing tau accumulation. However, whether
Externí odkaz:
https://doaj.org/article/aa5d96de944c46ac9e1724ca0b635269
Autor:
Shuangxue Han, Zhijun He, Xia Hu, Xiaoqian Li, Kaixin Zheng, Yingying Huang, Peng Xiao, Qingguo Xie, Jiazuan Ni, Qiong Liu
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 722 (2023)
The reduction of the cerebral glucose metabolism is closely related to the activation of the NOD-like receptor protein 3 (NLRP3) inflammasome in Alzheimer’s disease (AD); however, its underlying mechanism remains unclear. In this paper, 18F-flurode
Externí odkaz:
https://doaj.org/article/1a0c54f39917419f8e3c0d3215af5a44
Autor:
Liang Jiang, Yiqian Lu, Lin Zheng, Gaopeng Li, Lianchang Chen, Maona Zhang, Jiazuan Ni, Qiong Liu, Yan Zhang
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Selenium is an essential trace element, and selenocysteine (Sec, U) is its predominant form in vivo. Proteins that contain Sec are selenoproteins, whose special structural features include not only the TGA codon encoding Sec but a
Externí odkaz:
https://doaj.org/article/81ba8e74992e4c9bb7d10a8fcf17f68d
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Background: Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that affects millions of people worldwide. However, there are currently no reliable biomarkers for ASD diagnosis.Materials and Methods: The strategy of computational
Externí odkaz:
https://doaj.org/article/5f7d21cb9af44090a89a4d2964dc158f
Autor:
Zhijun He, Shuangxue Han, Huazhang Zhu, Xia Hu, Xiaoqian Li, Chaofan Hou, Chong Wu, Qingguo Xie, Nan Li, Xiubo Du, Jiazuan Ni, Qiong Liu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Alzheimer’s disease (AD) is a widely distributed neurodegenerative disease characterized clinically by cognitive deficits and pathologically by formation of amyloid-β (Aβ) plaque and neurofibrillary tangles (NFTs) in the brain. Vanadium is a biol
Externí odkaz:
https://doaj.org/article/dc737b0862384e938737f261ca0ce92b
Autor:
Jing Tian, Jiapan Liu, Jieqiong Li, Jingxin Zheng, Lifang Chen, Yujuan Wang, Qiong Liu, Jiazuan Ni
Publikováno v:
Nutrition & Metabolism, Vol 15, Iss 1, Pp 1-9 (2018)
Abstract Background Selenoprotein F (SELENOF, was named as 15-kDa selenoprotein) has been reported to play important roles in oxidative stress, endoplasmic reticulum (ER) stress and carcinogenesis. However, the biological function of SELENOF is still
Externí odkaz:
https://doaj.org/article/28e363032abd4606aff98e90b64a3bf3
Autor:
Fang Yao, Kaoyuan Zhang, Yan Zhang, Yi Guo, Aidong Li, Shifeng Xiao, Qiong Liu, Liming Shen, Jiazuan Ni
Publikováno v:
Frontiers in Neurology, Vol 9 (2019)
Background: Alzheimer's disease (AD) is the major cause of dementia in population aged over 65 years, accounting up to 70% dementia cases. However, validated peripheral biomarkers for AD diagnosis are not available up to present. In this study, we ad
Externí odkaz:
https://doaj.org/article/69f5bdae7c2a484485f27dacbe44142a
Autor:
Zhijun He, Wen Xiao, Nan Li, Jianxi Song, Chong Wu, Xiubo Du, Xiaoqian Li, Jiazuan Ni, Xuexia Li, Huazhang Zhu, Qiong Liu
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 26:551-568
Endoplasmic reticulum stress (ER stress) plays a critical role in neuronal apoptosis along with the aggravation of Alzheimer's disease (AD). Nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcriptio
Publikováno v:
Cells, Vol 8, Iss 5, p 479 (2019)
Changes of Selenoprotein F (SELENOF) protein levels have been reported during selenium supplementation, stressful, and pathological conditions. However, the mechanisms of how these external factors regulate SELENOF gene expression are largely unknown
Externí odkaz:
https://doaj.org/article/2c4c0615aec3418593bab28e2e8ec464
Autor:
Yan Zhang, Lianchang Chen, Lin Zheng, Maona Zhang, Qiong Liu, Jiazuan Ni, Gaopeng Li, Yiqian Lu, Liang Jiang
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
BMC Genomics
BMC Genomics
Background Selenium is an essential trace element, and selenocysteine (Sec, U) is its predominant form in vivo. Proteins that contain Sec are selenoproteins, whose special structural features include not only the TGA codon encoding Sec but also the S