Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jiazhong Cai"'
Autor:
Yu Lin, Zhifang Zhao, Wenqiang Nie, Manting Huang, Jiazhong Cai, Yadong Wang, Hesong Wang, Yongmei Huang, Yang Bai
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Colorectal cancer (CRC) is a harmful cancer with high morbidity and poor prognosis. There is growing evidence that RNA methylation is closely related to the occurrence of cancer and its malignant biological behavior. N6-methyladenosine (m
Externí odkaz:
https://doaj.org/article/d8d3cc92803d4bfc885129f6158b4e47
Autor:
Wenjia Lin, Shiying Liu, Zhuojian Huang, Haiwen Li, Tianyu Lu, Yongxin Luo, Jiamin Zhong, Zewen Xu, Yu Liu, Yanwu Li, Peiwu Li, Qian Xu, Jiazhong Cai, Huibiao Li, Xin-lin Chen
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
ObjectivesFor Crohn’s disease (CD), the alternation of the active phase and inactive phase may be related to humoral immunity and cellular immunity. This study aims to understand the characteristics of immune cells in patients with active CD (CDa)
Externí odkaz:
https://doaj.org/article/e4c45ca0ace844abbadb1fa07c6e1b7d
Autor:
Yongxin Luo, Shiying Liu, Huibiao Li, Jiangtao Hou, Wenjia Lin, Zewen Xu, Tianyu Lu, Yanwu Li, Bin Peng, Shijing Zhang, Xue Han, Zuoliang Kuang, Yi Wen, Jiazhong Cai, Fengbin Liu, Xin-Lin Chen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background: The pathogenesis of ulcerative colitis (UC) is closely related to immunity. The immune characteristic differences between active UC (UCa) and inactive UC (UCin) have not been completely explained. Mass cytometry (CyTOF) and single-cell RN
Externí odkaz:
https://doaj.org/article/5f04cef77b264171a9f3680b69394664
Autor:
Yulan Liu, Lan Xiao, Jian-Ying Wang, Shan Cao, Hong-Ying Wang, Myriam Gorospe, Jiazhong Cai, Sudhakar Kalakonda, Hee Kyoung Chung, Jaladanki N. Rao, Ning Chen, Xiao-Xue Li
Publikováno v:
Gastroenterology
Background & Aims Paneth cells secrete antimicrobial proteins including lysozyme via secretory autophagy as part of the mucosal protective response. The ELAV like RNA-binding protein 1 (ELAVL1, also called HuR) regulates stability and translation of
Autor:
Lin-Lin Chen, Yunzhan Zhang, Jiazhong Cai, Jaladanki N. Rao, Jian-Ying Wang, Xiang-Xue Ma, Lan Xiao, Hee K Chung
Publikováno v:
Am J Physiol Cell Physiol
Homeostasis of the intestinal epithelium is tightly regulated by numerous extracellular and intracellular factors including vitamin D and the vitamin D receptor (VDR). VDR is highly expressed in the intestinal epithelium and is implicated in many asp
Autor:
Yuqi Si, Xiaoyi Xin, Zhijun Deng, Zhisen Pan, Shaoxiang Xian, Jiazhong Cai, Shuangcheng Wu, Qingyin Huang, Haoxiang Wu, Junmei Zhang, Hong Liu, Haitao Tu, Chuangpeng Shen, Chong Zhong, Zhangzhi Zhu, Min Liu, Mingxuan Zheng, Zhangzhou Liu, Shaoyang Lan, Yuanyuan Yu, Jiewen Guo, Yanhua Zhong
Publikováno v:
Journal of Ethnopharmacology. 279:114340
Background Cassia mimosoides Linn (CMD) is a traditional Chinese herb that clears liver heat and dampness. It has been widely administered in clinical practice to treat jaundice associated with damp-heat pathogen and obesity. Emodin (EMO) is a major
Autor:
Jueyu Wang, Yong Gao, Zhao Chen, Guohui Zhang, Chuangpeng Shen, Da-ke Cai, Meijing Liu, Chao-Zhan Lin, Chen-Chen Zhu, Jiazhong Cai, Xin Jin, Chuanquan Lin, Yanwu Li, Meng Song, Changhui Liu
Publikováno v:
Journal of ethnopharmacology. 248
Ethnopharmacological relevance The pregnane-X-receptor (PXR) is involved in inflammatory bowel disease (IBD). Patchouli alcohol (PA) has anti-inflammatory effects; however, the effect of PA on IBD pathogenesis remains largely unknown. Aim of the stud
Publikováno v:
The FASEB Journal. 33
Autor:
Yueling Zhang, Shuqi Pu, Xiaoting Wu, Haiyong Jin, Yan Liu, Ruliu Li, Xiaoying Yang, Ling Hu, Xiaojie Wu, Yun-kai Dai, Yunzhan Zhang, Jianhong Cao, Yong Gao, Qizhi Cao, Jiazhong Cai, Xiaona Cui
Publikováno v:
Current drug metabolism. 20(1)
Background: Diabetes, with an increased prevalence and various progressive complications, has become a significant global health challenge. The concrete mechanisms responsible for the development of diabetes still remain incompletely unknown, althoug
Autor:
Lin Hu, Ruliu Li, Yong Gao, Lu Yao, Jinwei Zhong, Xiaojie Wu, Xiaoying Yang, Yanwu Li, Juji Dai, Jiazhong Cai, Xiaona Cui, Haiyong Jin, Yan Wang, Ke Chen, Qun Du
Publikováno v:
Current drug metabolism. 20(1)
Background: PXR (Pregnane X Receptor) and CAR (Constitutive Androstane Receptor) are termed as xenobiotic receptors, which are known as core factors in regulation of the transcription of metabolic enzymes and drug transporters. However, accumulating