Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jiazhao Xie"'
Autor:
Lu Tan, Jiazhao Xie, Chenqi Liao, Xiaoguang Li, Weiyun Zhang, Changchun Cai, Liming Cheng, Xiong Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Ferroptosis represents a nonapoptotic type of programmed cell death induced by excessive intracellular iron accumulation. Ferroptosis is an essential driver of the pathogenesis of Alzheimer’s disease (AD). Tetrahedral framework
Externí odkaz:
https://doaj.org/article/3d24e44d7a3f4c1a86415eb89e8dcff4
Autor:
Yang Gao, Yuying Wang, Huiyang Lei, Zhendong Xu, Shihong Li, Haitao Yu, Jiazhao Xie, Zhentao Zhang, Gongping Liu, Yao Zhang, Jie Zheng, Jian‑Zhi Wang
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/c5997c37c6234ecba8753c48a298e3c8
Autor:
Xiong Wang, Jiazhao Xie, Lu Tan, Yanjun Lu, Na Shen, Jiaoyuan Li, Hui Hu, Huijun Li, Xiaoguang Li, Liming Cheng
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-19 (2023)
Abstract Background Synaptic degeneration occurs in the early stage of Alzheimer's disease (AD) before devastating symptoms, strongly correlated with cognitive decline. Circular RNAs (circRNAs) are abundantly enriched in neural tissues, and aberrant
Externí odkaz:
https://doaj.org/article/2b2f0b20ab494595814f8a09a17d083b
Autor:
Yang Gao, Yuying Wang, Huiyang Lei, Zhendong Xu, Shihong Li, Haitao Yu, Jiazhao Xie, Zhentao Zhang, Gongping Liu, Yao Zhang, Jie Zheng, Jian-Zhi Wang
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-15 (2023)
Abstract Background Intraneuronal accumulation of hyperphosphorylated tau is a defining hallmark of Alzheimer’s disease (AD). However, mouse models imitating AD-exclusive neuronal tau pathologies are lacking. Methods We generated a new tet-on trans
Externí odkaz:
https://doaj.org/article/2c87f6cabb794cbcb2d49af1789302e8
Autor:
Dongqin Wu, Nana Yu, Yang Gao, Rui Xiong, Luping Liu, Huiyang Lei, Sen Jin, Jiale Liu, Yingzhou Liu, Jiazhao Xie, Enjie Liu, Qiuzhi Zhou, Yanchao Liu, Shihong Li, Linyu Wei, Jingru Lv, Huilin Yu, Wenbo Zeng, Qiang Zhou, Fuqiang Xu, Min-Hua Luo, Yao Zhang, Ying Yang, Jian-Zhi Wang
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background Abnormal tau accumulation and cholinergic degeneration are hallmark pathologies in the brains of patients with Alzheimer’s disease (AD). However, the sensitivity of cholinergic neurons to AD-like tau accumulation and strategies
Externí odkaz:
https://doaj.org/article/39fe4c579b394e849b92ba74dcf1104c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Brain infiltration of the natural killer (NK) cells has been observed in several neurodegenerative disorders, including Parkinson’s disease (PD). In a mouse model of α-synucleinopathy, it has been shown that NK cells help in clearing α-synuclein
Externí odkaz:
https://doaj.org/article/e938f7af62874dacac715f552417928f
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Alternative splicing (AS) is a common phenomenon and correlates with aging and aging-related disorders including Alzheimer’s disease (AD). We aimed to systematically characterize AS changes in the cerebral cortex of 9-month-old APP/PS1 mice. The GS
Externí odkaz:
https://doaj.org/article/25d3a3fd74994e72ab500c92ba0897d0
Publikováno v:
Aging. 14:6554-6566
Numerous alternative splicing (AS) events have been documented in Alzheimer's disease (AD). However, cell type-specific AS analysis is still lacking. We described AS events in the hippocampal microglia sorted by CD45 and CD11b from Aβ precursor prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb45bb3c82402bc74472023aa79ff8a
https://doi.org/10.18632/aging.204223
https://doi.org/10.18632/aging.204223
Background Elevated serum homocysteine (Hcy) is an independent risk factor of Alzheimer’s disease (AD). It has been reported that Hcy dramatically accelerates the aging of endothelial progenitor cells or endothelial cells. However, whether and how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a4deca03f02a95c660a1ebe7da977cf
https://doi.org/10.21203/rs.3.rs-1120464/v1
https://doi.org/10.21203/rs.3.rs-1120464/v1
Publikováno v:
Frontiers in Immunology; 9/20/2022, Vol. 13, p1-10, 10p