Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jiayin Bao"'
Publikováno v:
Pharmaceutical Chemistry Journal. 54:1033-1039
Solid dispersions (SDs) containing co-carrier were developed to improve in vitro dissolution and in vivo pharmacokinetics of celecoxib (CXB). Various polymers, including PVP K30, PEG4000, PEG6000, Poloxamer 188, Eudragit E100 and colloidal SiO2, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca8f44375fb7293fbb203258fefd3f5d
https://doi.org/10.1007/s11094-021-02316-0
https://doi.org/10.1007/s11094-021-02316-0
Autor:
Haiyu, Chen, Qiuqing, Ke, Guoxing, Weng, Jiayin, Bao, Jie, Huang, Licheng, Yan, Fuzhen, Zheng
Publikováno v:
Am J Transl Res
Objective: This study was designed to investigate the risk factors of postoperative acute kidney injury (AKI) in patients with complex congenital heart disease (CHD) and the significance of early detection of serum transcription factor Nkx2.5. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66cd80287538fa6f81db1e8fc9e020e2
https://pubmed.ncbi.nlm.nih.gov/34306387
https://pubmed.ncbi.nlm.nih.gov/34306387
BACKGROUNDː This study compared the perioperative and follow-up period data of patients who underwent redo tricuspid valve replacements performed via thoracoscopic surgery or median sternotomy. The purpose was to evaluate the feasibility, safety, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e7ad1106e7c1edd9afaae261bf1241
https://doi.org/10.21203/rs.3.rs-17615/v1
https://doi.org/10.21203/rs.3.rs-17615/v1
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:408-415
In the present study, a febuxostat (FEB) solid dispersion was prepared via the solvent evaporation method, and the dispersion's solubility, dissolution rate and oral bioavailability were investigated. To select the appropriate carriers for the FEB so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33b6feee961900348269b5e7f4dc350e
https://doi.org/10.1016/j.jddst.2018.06.005
https://doi.org/10.1016/j.jddst.2018.06.005
Publikováno v:
Journal of Microencapsulation. 35:454-466
The research aimed to prepare febuxostat (FEB) solid dispersion through solvent evaporation. Optimised solid dispersion composed of FEB, polyvinylpyrrolidone (PVP K30) and poloxamer at a ratio of 1:3:3 was characterised. Powder X-ray diffraction (XRD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8a9e17b46c264b17c0cf4c02c4eb84
https://doi.org/10.1080/02652048.2018.1526339
https://doi.org/10.1080/02652048.2018.1526339
Autor:
Svetlana M. Krylova, Jiayin Bao, Sergey N. Krylov, Philip E. Johnson, S. S. Beloborodov, Agnesa Shala-Lawrence
Publikováno v:
Journal of Chromatography B. 1073:201-206
DNA aptamers are attractive capture probes for affinity chromatography since, in contrast to antibodies, they can be chemically synthesized and, in contrast to tag-specific capture probes (such as Nickel-NTA or Glutathione), they can be used for puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c932b28ae7793edb10e5f14a22467e6
https://doi.org/10.1016/j.jchromb.2017.12.024
https://doi.org/10.1016/j.jchromb.2017.12.024
Autor:
Nicolas Sisavath, Jean Luc Rukundo, J.C. Yves Le Blanc, Victor A. Galievsky, Jiayin Bao, Sven Kochmann, Alexander S. Stasheuski, Sergey N. Krylov
Current methods for finding the equilibrium dissociation constant, Kd, of protein-small molecule complexes have inherent sources of inaccuracy.We introduce “Accurate Kd via Transient Incomplete Separation” (AKTIS), an approach that is free of kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5f7f16964ffb6a8a1d9d551382fb73
https://doi.org/10.26434/chemrxiv.7607078
https://doi.org/10.26434/chemrxiv.7607078
Autor:
Haiyu Chen, Weiwei Zhang, Guoxing Weng, Shun Yu, Huan Wang, Jiayin Bao, Xiying Cao, Zhi Dou, Min Li
Publikováno v:
Experimental Biology and Medicine. 241:1819-1824
Embolus-related cerebral injury is still a serious adverse event after cardiopulmonary bypass (CPB). But there is no stable animal model for basic and clinical research purposes. We chose miniature pig to establish a stable animal model of embolus-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfea036e169bc8cce6fd900d2d8468d0
https://doi.org/10.1177/1535370216648804
https://doi.org/10.1177/1535370216648804
Autor:
Robert L. Hale, Sergey N. Krylov, Christopher C. Arico-Muendel, Jiayin Bao, Leonid T. Cherney, Alex Shaginian, Svetlana L. Belyanskaya, Svetlana M. Krylova, Cynthia H. Chiu
Publikováno v:
Analytical Chemistry. 88:5498-5506
Selection of target-binding ligands from DNA-encoded libraries of small molecules (DELSMs) is a rapidly developing approach in drug-lead discovery. Methods of kinetic capillary electrophoresis (KCE) may facilitate highly efficient homogeneous selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d29181ac67b48105e738365c19bece5
https://doi.org/10.1021/acs.analchem.6b00980
https://doi.org/10.1021/acs.analchem.6b00980
Autor:
J. C. Yves LeBlanc, Sergey N. Krylov, Philip E. Johnson, Jiayin Bao, Derek J. Wilson, Leonid T. Cherney, Patrick Pribil, Svetlana M. Krylova
Publikováno v:
Analytical Chemistry. 86:10016-10020
Studying the kinetics of reversible protein− small molecule binding is a major challenge. The available approaches require that either the small molecule or the protein be modified by labeling or immobilization on a surface. Not only can such modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c748b7607172395f6991313795568e83
https://doi.org/10.1021/ac503391c
https://doi.org/10.1021/ac503391c