Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jiaxiang Shen"'
Autor:
Chuanchau J. Jou, Cammon B. Arrington, Spencer Barnett, Jiaxiang Shen, Scott Cho, Xiaoming Sheng, Patrick C. McCullagh, Neil E. Bowles, Chase M. Pribble, Elizabeth V. Saarel, Thomas A. Pilcher, Susan P. Etheridge, Martin Tristani-Firouzi
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 5, Pp 2021-2029 (2017)
Background/Aims: Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe bradycardia and prolonged pauses. Mutations in HCN4, the gene encoding inward Na+/K+ current (If), have been described as a cause o
Externí odkaz:
https://doaj.org/article/7737dfc076d945d09d15b2a1c15f6913
Autor:
Patrick C McCullagh, Susan P. Etheridge, Chase Pribble, Xiaoming Sheng, Spencer M. Barnett, Martin Tristani-Firouzi, Elizabeth V. Saarel, Cammon B. Arrington, Neil E. Bowles, Jiaxiang Shen, Chuanchau J. Jou, Thomas A. Pilcher, Scott Cho
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 5, Pp 2021-2029 (2017)
Background/Aims: Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe bradycardia and prolonged pauses. Mutations in HCN4, the gene encoding inward Na+/K+ current (If), have been described as a cause o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dda2af977b01203729c8b4ac892617
https://doi.org/10.1159/000479897
https://doi.org/10.1159/000479897
Publikováno v:
Documenta ophthalmologica. Advances in ophthalmology. 138(2)
Glaucoma is a common chronic neurodegenerative disease, which could lead to visual loss. In this study, we aimed to investigate whether fisetin, a natural flavone with anti-inflammatory and antioxidant properties, is able to alleviate glaucoma. We em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fc412e959900b0d27733eaf3281a09
https://pubmed.ncbi.nlm.nih.gov/31729593
https://pubmed.ncbi.nlm.nih.gov/31729593
Autor:
Jiaxiang Shen, Xianghai Guo
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 145:657-661
A green and practical method for the synthesis of thymine was established by using methyl acrylate under hydroformylation conditions to give the important intermediate methyl α-formylpropionate. The incorporation of this protocol into the synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24cd4f59821ee9806be547ac9ffc6756
https://doi.org/10.1007/s00706-013-1128-y
https://doi.org/10.1007/s00706-013-1128-y
Publikováno v:
Documenta Ophthalmologica. 139:169-169
The Editor-in-Chief of Documenta Ophthalmologica is publishing an editorial expression of concern for the manuscript "Fisetin rescues retinal functions by suppressing inflammatory response in a DBA/2J mouse model of glaucoma” by Li et al. (2019) [1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faff6fb88121d38de9e1ab6e26d08c42
https://doi.org/10.1007/s10633-019-09737-z
https://doi.org/10.1007/s10633-019-09737-z
Publikováno v:
Synthetic Communications. 41:2044-2052
An efficient and practical method for the synthesis of indole as a key starting material for many useful chemicals is described. Using 2-nitrotoluene as starting material, hydroxymethylation with formaldehyde under alkaline conditions gave 2-(2-nitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3b42d0aab975ec52c478afd1644ce10
https://doi.org/10.1080/00397911.2010.495828
https://doi.org/10.1080/00397911.2010.495828
Publikováno v:
Synlett. 2010:1959-1962
The synthesis of a new clitocine derivative was achieved through a convergent strategy. A protected 4,6-diamino-5-nitro-pyrimidine was condensed with p-chlorobenzoyl (PCB)-protected methyl 3'-azido-2',3'-dideoxyribofuranoside, followed by subsequentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ae0c3a0e858308075636734c917fa6
https://doi.org/10.1055/s-0030-1258503
https://doi.org/10.1055/s-0030-1258503
Autor:
Jennifer L. Robinson, Peter J. Schwartz, Michael H. Lehmann, G. Michael Vincent, Igor Splawski, Arthur J. Moss, Silvia G. Priori, Jiaxiang Shen, Mark T. Keating, Katherine W. Timothy, Jeffrey A. Towbin
Publikováno v:
Circulation. 102:1178-1185
Background —Long-QT Syndrome (LQTS) is a cardiovascular disorder characterized by prolongation of the QT interval on ECG and presence of syncope, seizures, and sudden death. Five genes have been implicated in Romano-Ward syndrome, the autosomal dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694dea925bbe19ce8ef26a2c3d24bdb5
https://doi.org/10.1161/01.cir.102.10.1178
https://doi.org/10.1161/01.cir.102.10.1178
Autor:
Donald L. Atkinson, Jiaxiang Shen, Michael C. Sanguinetti, M T Keating, Anruo Zou, Mark E. Curran, Peter S. Spector
Publikováno v:
Nature. 384:80-83
THE slowly activating delayed-rectifier K+ current, IKS, modulates the repolarization of cardiac action potentials. The molecular structure of the IKS channel is not known, but physiological data indicate that one component of theIKSchannel is minK (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc209ffd5668b7f2de445688bb47e83
https://doi.org/10.1038/384080a0
https://doi.org/10.1038/384080a0
Publikováno v:
Genomics. 34:9-16
The voltage-gated cardiac sodium channel, SCN5A, is responsible for the initial upstroke of the action potential. Mutations in the human SCN5A gene cause susceptibility to cardiac arrhythmias and sudden death in the long QT syndrome (LQT). In this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::661c507fd53840f17c132cc3a7502253
https://doi.org/10.1006/geno.1996.0236
https://doi.org/10.1006/geno.1996.0236