Zobrazeno 1 - 10
of 692
pro vyhledávání: '"Jiaxi Xu"'
Autor:
Xingjuan Chen, Yunzheng Yan, Zhiqiang Liu, Shaokang Yang, Wei Li, Zhuang Wang, Mengyuan Wang, Juan Guo, Zhenyang Li, Weiyan Zhu, Jingjing Yang, Jiye Yin, Qingsong Dai, Yuexiang Li, Cui Wang, Lei Zhao, Xiaotong Yang, Xiaojia Guo, Ling Leng, Jiaxi Xu, Alexander G Obukhov, Ruiyuan Cao, Wu Zhong
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1817-1839 (2024)
Abstract Zika virus (ZIKV) infection may lead to severe neurological consequences, including seizures, and early infancy death. However, the involved mechanisms are still largely unknown. TRPC channels play an important role in regulating nervous sys
Externí odkaz:
https://doaj.org/article/f40606a0be644b1b80177e9be7140294
Publikováno v:
Brain Research Bulletin, Vol 214, Iss , Pp 110994- (2024)
Synaptotagmin-7 (SYT7) has been proposed as an innovative therapeutic strategy for treating cognitive impairment, while its contribution to Alzheimer’s disease (AD) alleviation remains unclear. In this study, we investigated the role and potential
Externí odkaz:
https://doaj.org/article/7b950cc6f92348a0ab50b3285fa3967c
Autor:
Jiaxi Xu, Hui Zeng, Guochao Zhang, Renda Li, Zhenlong Yuan, Jingyu Ren, Yufei Huang, Fangzhou Ren, Hao Zhang, Kailun Fei, Feiyue Feng, Fengwei Tan
Publikováno v:
Thoracic Cancer, Vol 14, Iss 31, Pp 3108-3118 (2023)
Abstract Background This study aimed to establish a nomogram for predicting risk of recurrence and provide a model for decision‐making between lobectomy and sublobar resection in patients with stage IA lung adenocarcinoma. Methods Patients diagnose
Externí odkaz:
https://doaj.org/article/98c6070734d4449aaf61b067df38f264
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0289248 (2024)
BackgroundAgomelatine (AGO) is an antidepressant with unique pharmacological effects; however, its underlying mechanisms remain unknown. In this study, we examined agomelatine's effects on catalase activity, oxidative stress, and inflammation.Methods
Externí odkaz:
https://doaj.org/article/47fe3339aa704853a4c7a3d903265f37
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
BackgroundAs the impact of COVID-19 on normal production and living conditions diminishes, this serious emergency is come to an end. China’s policy framework has facilitated positive adjustment over the past 3 years by timely modifying its emergenc
Externí odkaz:
https://doaj.org/article/78ad7f25d74545828da4317e1e627ef5
Autor:
Jiaxi Xu
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 687-699 (2023)
Phostams, phostones, and phostines are a series of 1,2-azaphosphaheterocycle and 1,2-oxaphosphaheterocycle 2-oxide derivatives. They are phosphorus analogues of lactams and lactones and important biologically active compounds. The strategies for the
Externí odkaz:
https://doaj.org/article/db669f7bcb884cadb803101ded9e9ff9
Publikováno v:
Molecules, Vol 29, Iss 13, p 2978 (2024)
The PyBox–La(OTf)3-catalyzed enantioselective Diels–Alder cycloaddition of 2-alk-2-enoylpyridines with cyclopentadiene is realized, producing enantiopure disubstituted norbornenes, which possess four contiguous stereocenters and are biologically
Externí odkaz:
https://doaj.org/article/eea3f851c4f748c4ad6b277922b8a716
Publikováno v:
Molecules, Vol 29, Iss 9, p 1963 (2024)
The chiral aziridine-containing vicinal iminophenol tridentate ligands (named salazins) are a class of readily prepared chiral ligands from enantiopure aziridines and salicylaldehydes. Their scandium and yttrium triflate complexes show excellent reac
Externí odkaz:
https://doaj.org/article/9c952a9f182f4dacb68d1ad10cdf1d89
Autor:
Jiaxi Xu
Publikováno v:
Molecules, Vol 29, Iss 7, p 1454 (2024)
The π-stacking interaction is one of the most important intramolecular and intermolecular noncovalent interactions in organic chemistry. It plays an important role in stabilizing some structures and transition states in certain reactions via both in
Externí odkaz:
https://doaj.org/article/76116eca0bd04c1a85b0a52dfd915ef8
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 214 (2024)
Ulcerative colitis is an inflammatory bowel disease with multiple pathogeneses. Here, we aimed to study the therapeutic role of ulinastatin (UTI), an anti-inflammatory bioagent, and its associated mechanisms in treating colitis. Dextran sulfate sodiu
Externí odkaz:
https://doaj.org/article/2588e721cf5d474abfcbb146636962b4