Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jiawu Zhao"'
Autor:
Senbuer Bao, Qizhi Chen, Wenjiang Shi, Peng Wang, Yanwei Wang, Shuwei Zhang, Lixin Wang, Deyuan Zou, Shuai Dong, Fanxing Meng, Jiawu Zhao, Shujun Xiang
Publikováno v:
Materials Research Express, Vol 11, Iss 6, p 065006 (2024)
The physical mixing of inorganic fillers and a polymer matrix is a common method for constructing superhydrophobic coatings. Nevertheless, the interface bonding strength between the polymer and nanofiller was weak. The construction of interacting cov
Externí odkaz:
https://doaj.org/article/e41dbde985a54c2e9a976ec469cd32e3
Publikováno v:
Cells, Vol 13, Iss 2, p 113 (2024)
Low-dose aspirin (LDA) is efficacious in preventing preeclampsia, but its mechanism of action is unclear. Conflicting evidence suggests that it may inhibit placental trophoblast release of soluble fms-like tyrosine kinase-1 (sFlt1), a key mediator of
Externí odkaz:
https://doaj.org/article/d2327c7727c54a95b118b414b48d9920
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Pre-eclampsia (PE) is increased ~4-fold by maternal diabetes. Elevated plasma antiangiogenic factors, soluble fms-like tyrosine kinase (sFLT-1) and soluble endoglin (sENG), precede PE onset. We investigated whether diabetes-related stres
Externí odkaz:
https://doaj.org/article/a1868336f5cf4185930e78f9d0f7cf4b
Autor:
Mei Chen, Jose R Hombrebueno, Chang Luo, Rosana Penalva, Jiawu Zhao, Liza Colhoun, Sudha Pirya Soundara Pandi, John V Forrester, Heping Xu
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61381 (2013)
Previous studies have shown that CCL2/CX3CR1 deficient mice on C57BL/6N background (with rd8 mutation) have an early onset (6 weeks) of spontaneous retinal degeneration. In this study, we generated CCL2(-/-)CX3CR1(GFP/GFP) mice on the C57BL/6J backgr
Externí odkaz:
https://doaj.org/article/4196744f55274fb18c65bf0d1e52bc03
Autor:
Jeremy Y. Yu, Jiawu Zhao, Michelle B. Hookham, Rebecca P. Chow, Rebecca H. McLeese, Timothy J. Lyons
Publikováno v:
Zhao, J, Chow, R P, McLeese, R H, Hookham, M B, Lyons, T J & Yu, J Y 2020, ' Modelling Preeclampsia: A Comparative Analysis of the Common Human Trophoblast Cell Lines ', FASEB BioAdvances . https://doi.org/10.1096/fba.2020-00057
FASEB BioAdvances
FASEB BioAdvances
Preeclampsia remains a challenge without an effective therapy. Evidence supports targetability of soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and soluble endoglin (sEng), which are released excessively from the placenta under ischemic and hypox
Publikováno v:
Chen, M, Luo, C, Zhao, J, Devarajan, G & Xu, H 2019, ' Immune regulation in the aging retina ', Progress in Retinal and Eye Research, vol. 69, pp. 159-172 . https://doi.org/10.1016/j.preteyeres.2018.10.003
The retina is an immune privileged tissue, which is protected from external and internal insults by its blood-retinal barriers and immune suppressive microenvironment. Apart from the avoidance and tolerance strategies, the retina is also protected by
Publikováno v:
BMJ Open Diabetes Research & Care
McLeese, R H, Zhao, J, Fu, D, Yu, J Y, Brazil, D P & Lyons, T J 2021, ' Effects of modified lipoproteins on human trophoblast cells: a role in pre-eclampsia in pregnancies complicated by diabetes ', BMJ open diabetes research & care, vol. 9, e001696 . https://doi.org/10.1136/bmjdrc-2020-001696
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
McLeese, R H, Zhao, J, Fu, D, Yu, J Y, Brazil, D P & Lyons, T J 2021, ' Effects of modified lipoproteins on human trophoblast cells: a role in pre-eclampsia in pregnancies complicated by diabetes ', BMJ open diabetes research & care, vol. 9, e001696 . https://doi.org/10.1136/bmjdrc-2020-001696
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
IntroductionPre-eclampsia (PE) is increased ~4-fold by maternal diabetes. Elevated plasma antiangiogenic factors, soluble fms-like tyrosine kinase (sFLT-1) and soluble endoglin (sENG), precede PE onset. We investigated whether diabetes-related stress
Publikováno v:
Diabetes. 68
Preeclampsia is a life-threatening complication of pregnancy that occurs four times more frequently in the presence of maternal diabetes. The anti-angiogenic factor soluble fms-like tyrosine kinase-1 (sFlt1), released from the placenta, plays a cruci
Autor:
Giuliana Silvestri, Judith Lechner, Mei Chen, Jiawu Zhao, Levente Toth, Usha Chakravarthy, Heping Xu, Ruth E Hogg, Adrien Kissenpfennig
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Current Molecular Medicine
Europe PubMed Central
Current Molecular Medicine
Infiltrating macrophages are critically involved in pathogenic angiogenesis such as neovascular agerelated macular degeneration (nAMD). Macrophages originate from circulating monocytes and three subtypes of monocyte exist in humans: classical (CD14(+
Publikováno v:
Diabetes. 67
Preeclampsia (PE) complicates 2-8% of pregnancies worldwide. In women with diabetes, the risk for PE is substantially increased by approximately 4 fold. Evidence indicates that an increased release of two anti-angiogenic factors, soluble fms-like tyr