Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jiawang Zhu"'
Publikováno v:
Chinese Journal of Lung Cancer, Vol 23, Iss 12, Pp 1066-1072 (2020)
Background and objective To compare the clinical efficacy of stereotactic body radiotherapy (SBRT) versus surgery for early-stage non-small cell lung cancer through evidence based medicine analysis. Methods A systematic search was performed in the Pu
Externí odkaz:
https://doaj.org/article/47e4c6becb6f4353997b5891552096b2
Autor:
Smriti Joseph, Janan Jona, Jason Brooks Human, Leyla Arik, Gondi N. Kumar, Toshihiro Aya, Randall W. Hungate, Jian J. Chen, Kaustav Biswas, Tanya Peterkin, Jiawang Zhu, Zufan Wu, Wenyuan Qian, Hong-Xun Guo, Eileen Johnson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:1061-1067
In a series of bradykinin B1 antagonists, we discovered that replacement of oxopiperazine acetamides with dehydro-oxopiperazine acetamides provided compounds with enhanced activity against the B1 receptor. The synthesis and SAR leading to potent anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebdb6efcda7e8ebe5c15c876f3b315d
https://doi.org/10.1016/j.bmcl.2011.11.112
https://doi.org/10.1016/j.bmcl.2011.11.112
Autor:
Yuelie Lu, Ling Wang, Michael Handley, Ning Xi, Stephen Arvedson, Andrew Tasker, Jiandong Zhang, Tingjian Xiang, Osslund Timothy D, Celia Dominguez, Qi Huang, Liang Huang, David Powers, Nianhe Han, Gladys Nunez, Qingyian Liu, Jiawang Zhu, Shawn Eisenberg, Shimin Xu, Alexander S. Kiselyov, Richard Kendall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:2905-2909
Novel αvβ3 antagonists based on the N-aryl-γ-lactam scaffold were prepared. SAR studies led to the identification of potent antagonists for αvβ3 receptor with excellent selectivity against the structurally related αIIbβ3 receptor. Additional i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6327503f49e45e3cee545d9f88871868
https://doi.org/10.1016/j.bmcl.2004.03.033
https://doi.org/10.1016/j.bmcl.2004.03.033
Publikováno v:
Journal of the American Chemical Society. 120:6690-6697
Two types of silylcarbocyclization reactions (SiCaCs) of 1,6-diynes are discussed: (i) silylcarbocyclization−hydrosilylation (SiCaC−HS) reactions giving 3-(silylmethylene)-4-(silylmethyl)pyrrolidi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef58818f26172a1072e5647d9c0d99ba
https://doi.org/10.1021/ja980907l
https://doi.org/10.1021/ja980907l
Publikováno v:
The Journal of Organic Chemistry. 62:7704-7710
Optically active chromium aminocarbene complexes were α-alkylated and then photolyzed in the presence of 2,4,5-trichlorophenol to produce a number of optically active activated α-amino esters. These underwent coupling with amino acid esters or a so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41b531e95847d94d9f1d49d344706d97
https://doi.org/10.1021/jo9709817
https://doi.org/10.1021/jo9709817
Autor:
Tom Nguyen, Mary Vedamuthu, Jiawang Zhu, Mary Chung, Chul Hee Cho, Shihua Yao, G. Wilse Robinson, Surjit Singh, J. Lee
Publikováno v:
The Journal of Physical Chemistry. 99:7806-7812
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::790569629414f10f71d67497aec92f6c
https://doi.org/10.1021/j100019a070
https://doi.org/10.1021/j100019a070
Autor:
Tanya Peterkin, Kaustav Biswas, Neil G. Andersen, Babak Riahi, Jian J. Chen, Gondi N. Kumar, Janan Jona, Kevin Yang, Judy Wang, Derin C. D'amico, Jason Brooks Human, Benny C. Askew, Thomas T. Nguyen, Qingyian Liu, Augustus Kamassah, Margaret M. Faul, Nobuko Nishimura, Christopher H. Fotsch, Wenyuan Qian, Eileen Johnson, Jiawang Zhu, Toshihiro Aya, Nianhe Han, Randall W. Hungate, John T. Colyer
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(11)
The discovery of novel and highly potent oxopiperazine based B1 receptor antagonists is described. Compared to the previously described arylsulfonylated (R)-3-amino-3-phenylpropionic acid series, the current compounds showed improved in vitro potency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb9aeb3661b15590aeaea60c2a5a66d
https://pubmed.ncbi.nlm.nih.gov/21514825
https://pubmed.ncbi.nlm.nih.gov/21514825
Autor:
Louis S. Hegedus, Jiawang Zhu
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c748c1105b86c7146c6d6cda0f1d1c3
https://doi.org/10.1002/chin.199603207
https://doi.org/10.1002/chin.199603207
Publikováno v:
ChemInform. 28
The silylcarbobicyclization of 4,4-disubstituted 1,6-heptadiynes with tert-butyldimethylsilane catalyzed by Rh(acac)(CO)2, Co2Rh2(CO)12, or (t-BuNC)4RhCo(CO)4 under 50 atm of carbon monoxide gives ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caf6235d22d3d6697e520cd71ea40d6a
https://doi.org/10.1002/chin.199712081
https://doi.org/10.1002/chin.199712081
Publikováno v:
ChemInform. 29
Optically active chromium aminocarbene complexes were α-alkylated and then photolyzed in the presence of 2,4,5-trichlorophenol to produce a number of optically active activated α-amino esters. These underwent coupling with amino acid esters or a so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9669167dbee6d14a5e0e001a0fe5146
https://doi.org/10.1002/chin.199813174
https://doi.org/10.1002/chin.199813174