Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jiaoyao Ma"'
Autor:
Yiyun Lou, Jiaoyao Ma, Yangnan Hu, Xiaoying Yao, Yaoqian Liu, Mingxuan Wu, Gaogan Jia, Yan Chen, Renjie Chai, Mingyu Xia, Wenyan Li
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract The physiological interactions between the peripheral and central auditory systems are crucial for auditory information transmission and perception, while reliable models for auditory neural circuits are currently lacking. To address this is
Externí odkaz:
https://doaj.org/article/14b5eceb7bc94fb2bc9fbe5259a7e7c4
Autor:
Mingyu Xia, Jiaoyao Ma, Mingxuan Wu, Luo Guo, Yan Chen, Geng-lin Li, Shan Sun, Renjie Chai, Huawei Li, Wenyan Li
Publikováno v:
Stem Cell Reports, Vol 18, Iss 1, Pp 319-336 (2023)
Summary: Functional cochlear hair cells (HCs) innervated by spiral ganglion neurons (SGNs) are essential for hearing, whereas robust models that recapitulate the peripheral auditory circuity are still lacking. Here, we developed cochlear organoids wi
Externí odkaz:
https://doaj.org/article/16a3a833ebe541f2b7af9bbf1f3af42a
Autor:
Xiaoling Lu, Huiqian Yu, Jiaoyao Ma, Kunkun Wang, Luo Guo, Yanping Zhang, Boan Li, Zehang Zhao, Huawei Li, Shan Sun
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Mammalian sensory hair cells (HCs) have limited capacity for regeneration, which leads to permanent hearing loss after HC death. Here, we used in vitro RNA-sequencing to show that the Hippo signaling pathway is involved in HC damage and self
Externí odkaz:
https://doaj.org/article/861a0c7295b449579d604e0fa8535a2c
Autor:
Cheng Cheng, Jiaoyao Ma, Xiaoling Lu, Panpan Zhang, Xiaohan Wang, Luo Guo, Peifan Li, Ying Wei, Geng-Lin Li, Xia Gao, Yuqiu Zhang, Renjie Chai, Huawei Li, Shan Sun
Publikováno v:
Neurobiology of Disease, Vol 183, Iss , Pp 106176- (2023)
Aminoglycoside antibiotics (AGAs) are widely used in life-threatening infections, but they accumulate in cochlear hair cells (HCs) and result in hearing loss. Increases in adenosine triphosphate (ATP) concentrations and P2X7 receptor expression were
Externí odkaz:
https://doaj.org/article/1cfb90319a0a41a699a1658c273fb20a
Publikováno v:
Neural Plasticity, Vol 2020 (2020)
Tinnitus, which is the perception of sound in the absence of a corresponding external acoustic stimulus, including change of hearing and neural plasticity, has become an increasingly important ailment affecting the daily life of a considerable propor
Externí odkaz:
https://doaj.org/article/a58abc8dde224955a1345e3f94bec9f6
Publikováno v:
Neural Plasticity, Vol 2018 (2018)
Sudden sensorineural hearing loss (SSHL) is a clinically common acute symptom in otolaryngology. Although the incidence of SSHL has increased around the world in recent years, the etiology of the disease is still unclear. It has been reported that in
Externí odkaz:
https://doaj.org/article/f325e31dae46418ea3b1161eceb25819
Autor:
Mingyu Xia, Jiaoyao Ma, Mingxuan Wu, Luo Guo, Yan Chen, Geng-lin Li, Shan Sun, Renjie Chai, Huawei Li, Wenyan Li
Publikováno v:
Stem cell reports.
Functional cochlear hair cells (HCs) innervated by spiral ganglion neurons (SGNs) are essential for hearing, whereas robust models that recapitulate the peripheral auditory circuity are still lacking. Here, we developed cochlear organoids with functi
Publikováno v:
Hearing research. 407
Loss of hair cells (HCs) accounts for most sensorineural hearing loss, and regeneration of cochlear HCs is considered as the ultimate strategy for restoring hearing. Several lines of evidence have shown that Lgr5+ progenitor cells can spontaneously r
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2018 (2018)
Neural Plasticity, Vol 2018 (2018)
Sudden sensorineural hearing loss (SSHL) is a clinically common acute symptom in otolaryngology. Although the incidence of SSHL has increased around the world in recent years, the etiology of the disease is still unclear. It has been reported that in
Bone morphogenetic proteins (BMPs) are the largest subfamily of the transforming growth factor-β superfamily, and they play important roles in the development of numerous organs, including the inner ear. The inner ear is a relatively small organ but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1797f6d9a845ee983f2bf0f29b0c4e
https://europepmc.org/articles/PMC6381002/
https://europepmc.org/articles/PMC6381002/