Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jiaoling Chen"'
Autor:
Xin Tang, Jiaqi Wang, Jiaoling Chen, Wanting Liu, Pei Qiao, Huiyi Quan, Zhiguo Li, Erle Dang, Gang Wang, Shuai Shao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract The skin epidermis is continually influenced by a myriad of internal and external elements. At its basal layer reside epidermal stem cells, which fuels epidermal renovation and hair regeneration with powerful self-renewal ability, as well as
Externí odkaz:
https://doaj.org/article/7dc8567f10ca4f9fb627beba63ffbba1
Autor:
Jiaoling Chen, Yaxing Bai, Ke Xue, Zhiguo Li, Zhenlai Zhu, Qingyang Li, Chen Yu, Bing Li, Shengxian Shen, Pei Qiao, Caixia Li, Yixin Luo, Hongjiang Qiao, Erle Dang, Wen Yin, Johann E. Gudjonsson, Gang Wang, Shuai Shao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Neutrophils have a pathogenic function in inflammation via releasing pro-inflammatory mediators or neutrophil extracellular traps (NETs). However, their heterogeneity and pro-inflammatory mechanisms remain unclear. Here, we demonstrate that
Externí odkaz:
https://doaj.org/article/a172614790d5444b9e797f479b8ca744
Autor:
Qingyang Li, Shuai Shao, Zhenlai Zhu, Jiaoling Chen, Junfeng Hao, Yaxing Bai, Bing Li, Erle Dang, Gang Wang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Dysfunction of vascular endothelial cells (ECs) facilitates imbalanced immune responses and tissue hyperinflammation. However, the heterogeneous functions of skin ECs and their underlying mechanism in dermatoses remain to be determined. Here, focusin
Externí odkaz:
https://doaj.org/article/53ec58ac014d49129ec697e9fbd7e72b
Autor:
Yixin Luo, Zhenlai Zhu, Bing Li, Xiaocui Bai, Hui Fang, Pei Qiao, Jiaoling Chen, Chen Zhang, Dalong Zhi, Erle Dang, Gang Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity response to skin contact allergens in which keratinocytes are critical in the initiation of early responses. Keratin 17 (K17) is a cytoskeletal protein inducible under stressful con
Externí odkaz:
https://doaj.org/article/e51c4bdd280c4f1ab7b9f75058fe5085
Autor:
Shuai Shao, Jiaoling Chen, William R. Swindell, Lam C. Tsoi, Xianying Xing, Feiyang Ma, Ranjitha Uppala, Mrinal K. Sarkar, Olesya Plazyo, Allison C. Billi, Rachael Wasikowski, Kathleen M. Smith, Prisca Honore, Victoria E. Scott, Emanual Maverakis, J. Michelle Kahlenberg, Gang Wang, Nicole L. Ward, Paul W. Harms, Johann E. Gudjonsson
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
Altered epidermal differentiation along with increased keratinocyte proliferation is a characteristic feature of psoriasis and pityriasis rubra pilaris (PRP). However, despite this large degree of overlapping clinical and histologic features, the mol
Externí odkaz:
https://doaj.org/article/b201715a6d7340b8bcc4b0a37d7e6e2f
Autor:
FEI SHA, DAISHAN XIN, JUN XU, ZHIWEI ZHENG, WENXIN LIN, XIAORUI CAI, FEI LIN, MINGHAO ZHENG, JIAOLING CHEN
Publikováno v:
Biocell; 2024, Vol. 48 Issue 3, p443-451, 9p
Autor:
Tianyu Cao, Xu Yuan, Hui Fang, Jiaoling Chen, Ke Xue, Zhiguo Li, Erle Dang, Gang Wang, Shuai Shao
Publikováno v:
Experimental Dermatology. 32:368-378
The infiltration of neutrophils in the epidermis and the release of neutrophil extracellular traps (NETs) are important events in the pathogenesis of psoriasis, but the regulatory roles and internal mechanism of NETs in psoriasis are largely unknown.
Autor:
JinLei Yu, Pu Song, YaXing Bai, Erle Dang, Yixin Luo, Jiaoling Chen, Meng Fu, Jieyu Zhang, Pei Qiao, Wei Guo, Gang Wang, Shuai Shao
Publikováno v:
Journal of Investigative Dermatology.
Background: Obesity is associated with an increased risk of atopic dermatitis (AD) and may accelerate its development. Keratinocyte dysfunction has been observed in obesity-related skin diseases, including psoriasis and acanthosis nigricans, but is n
Autor:
Yixin Luo, Bingyu Pang, Junfeng Hao, Qingyang Li, Pei Qiao, Chen Zhang, Yaxing Bai, Chunying Xiao, Jiaoling Chen, Dalong Zhi, Ying Liu, Erle Dang, Gang Wang, Bing Li
Publikováno v:
International Journal of Biological Sciences; 2023, Vol. 19 Issue 11, p3395-3411, 17p
Autor:
Xianying Xing, Bogi Andersen, Alexander A. Merleev, Jiaoling Chen, Lam C. Tsoi, Joseph Kirma, Mrinal K. Sarkar, Chang Zeng, Robert L. Modlin, Shuai Shao, William R. Swindell, Rachael Wasikowski, Olesya Plazyo, Allison C. Billi, Matteo Pellegrini, Feiyang Ma, Johann E. Gudjonsson, Nicole L. Ward, Jingru Sun, Yanyun Jiang, J. Michelle Kahlenberg, Ranjitha Uppala, Stephan Weidinger, Emanual Michael Maverakis, Bethany E. Perez White, Paul W. Harms, Gang Wang, John J. Voorhees
Publikováno v:
J Invest Dermatol
The Journal of investigative dermatology, vol 141, iss 10
The Journal of investigative dermatology, vol 141, iss 10
Many inflammatory skin diseases are characterized by altered epidermal differentiation. Whether this altered differentiation promotes inflammatory responses has been unknown. Here, we show that IRAK2, a member of the signaling complex downstream of I