Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Jianzhong Shentu"'
Autor:
Jing Wu, Guolan Wu, Liangzhi Xie, Duo Lv, Chang Xu, Huili Zhou, Lihua Wu, Jingjing Zhang, Jianzhong Shentu
Publikováno v:
Drugs in R&D, Vol 23, Iss 2, Pp 175-183 (2023)
Abstract Background SCT510 is a recombinant humanized monoclonal antibody targeting vascular endothelial growth factor (VEGF), which is intended as a candidate biosimilar of bevacizumab that is approved for various metastatic cancers.Please confirm c
Externí odkaz:
https://doaj.org/article/fd1d35d60c1c4b679c36332c14da4253
Autor:
Zhijie Dai, Ronghua Zhu, Zhifeng Sheng, Guijun Qin, Xianghang Luo, Qun Qin, Chunli Song, Liping Li, Ping Jin, Guoping Yang, Yanxiang Cheng, Danhong Peng, Chong Zou, Lijuan Wang, Jianzhong Shentu, Qin Zhang, Zhe Zhang, Xiang Yan, Pingfei Fang, Qiangyong Yan, Lingfeng Yang, Xiao Fan, Wei Liu, Bo Wu, Rongrong Cui, Xiyu Wu, Yuting Xie, Chang Shu, Kai Shen, Wenhua Wei, Wei Lu, Hong Chen, Zhiguang Zhou
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
SHR-1222, a novel humanized monoclonal antibody targeting sclerostin, has been shown to induce bone formation and decrease bone resorption at a single dose ranging 50–400 mg in our previous phase 1 trial. This study was a randomized, double-blind,
Externí odkaz:
https://doaj.org/article/a89e55f5717f475a9a05befd69d69692
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Objective: Pharmacokinetic (PK) similarity between biosimilar candidate LRG201902 and European Union-sourced liraglutide reference product (Victoza®) was evaluated. Safety and immunogenicity were also assessed.Methods: This single-dose, randomized,
Externí odkaz:
https://doaj.org/article/acaa97258aa34e3b80aea3f5163530ee
Autor:
Lihua Wu, Zhe Zhang, Hainv Gao, Yuhua Li, Lihua Hou, Hangping Yao, Shipo Wu, Jian Liu, Ling Wang, You Zhai, Huilin Ou, Meihua Lin, Xiaoxin Wu, Jingjing Liu, Guanjing Lang, Qian Xin, Guolan Wu, Li Luo, Pei Liu, Jianzhong Shentu, Nanping Wu, Jifang Sheng, Yunqing Qiu, Wei Chen, Lanjuan Li
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 9, Pp 2078-2085 (2017)
Background: To determine the safety and immunogenicity of a novel recombinant adenovirus type 5 vector based Ebola virus disease vaccine (Ad5-EBOV) in Africans in China. Methods: A phase 1, dose-escalation, open-label trial was conducted. 61 healthy
Externí odkaz:
https://doaj.org/article/8ecc665b64cc4c5aa395a971db4e5a36
Autor:
Guolan Wu, Lihua Wu, Huili Zhou, Meihua Lin, Ling Peng, Yina Wang, You Zhai, Xingjiang Hu, Yunliang Zheng, Duo Lv, Jian Liu, Jianzhong Shentu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Purpose: The aim of this study was to compare the pharmacokinetics and safety between two vinorelbine formulations [a new oil-in-water emulsion formulation (ANX) versus a previously marketed solution formulation (Navelbine)] in Chinese patients with
Externí odkaz:
https://doaj.org/article/a455046d2af74312981059d239fdfda4
Autor:
Jianzhong Shentu, Guolan Wu, Junchun Chen, Xingjiang Hu, Huili Zhou, Jian Liu, Duo Lv, Lihua Wu
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Objective: A generic vaginal progesterone gel has recently been developed in China. Little is known about its pharmacokinetic properties in Chinese subjects. The purpose of our study was to investigate the pharmacokinetics of three forms of vaginal p
Externí odkaz:
https://doaj.org/article/264cf57a4ff44678abedc9cbd2ae4de4
Publikováno v:
Materials, Vol 5, Iss 12, Pp 2586-2596 (2012)
Quikclot has been used many years for treating external hemorrhage in the battle field. In this study, the hemostatic performance of NZG-JY (natural zeolite granules from Jinyun, China) was evaluated and compared with Quikclot in a lethal rabbit mode
Externí odkaz:
https://doaj.org/article/6f2cc30c770d480f8bc0b21426b3c2ae
Publikováno v:
Advances in Pharmacological Sciences, Vol 2014 (2014)
A simple, robust LC-MS/MS assay for quantifying cefuroxime in human plasma was developed. Cefuroxime and tazobactam, as internal standard (IS), were extracted from human plasma by methanol to precipitate protein. Separation was achieved on a Zorbax S
Externí odkaz:
https://doaj.org/article/81da5826793e4e44a0bcc302fae13357
Autor:
Yunliang Zheng, Xingjiang Hu, Jian Liu, Guolan Wu, Huili Zhou, Meixiang Zhu, You Zhai, Lihua Wu, Jianzhong ShenTu
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2014 (2014)
A highly sensitive, simple, and rapid liquid chromatography tandem mass spectrometry method to simultaneously determine blonanserin and blonanserin C in human plasma with AD-5332 as internal standard (IS) was established. A simple direct protein prec
Externí odkaz:
https://doaj.org/article/685413717722410eaa1646d7431e4dcf
Autor:
Lianlian, Fan, Peiwen, Zhang, Chunyan, Gan, Qian, Huang, Zhen, Shen, Xue, Xiao, Ying, Yang, Daicong, Qiu, Gang, Mai, Jianzhong, Shentu
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 61:37-44
The aims of this study were to evaluate and compare the pharmacokinetic profiles and bioequivalence of two tablet formulations of methylprednisolone (test formulation: Zhejiang Xianju Pharmaceutical Co., Ltd., China; reference formulation: Medrol, Pf