Using Local Anesthesia for Burr Hole Surgery of Chronic Subdural Hematoma Reduces Postoperative Complications, Length of Stay, and Hospitalization Cost: A Retrospective Cohort Study From a Single Center

Autor: Zerui Zhuang, Zelin Chen, Hui Chen, Bin Chen, Jianzhi Zhou, Anmin Liu, Jianming Luo

Publikováno v: Frontiers in Surgery, Vol 9 (2022)

PurposeThe purpose of the current study was to compare the effects of local anesthesia (LA) and general anesthesia (GA) on the surgical process and postoperative recovery of patients with unilateral chronic subdural hematoma (CSDH).Patients and Metho

Externí odkaz: https://doaj.org/article/af73126427434cccaa9c0c255555dc2c

Prenatal exposure to lipopolysaccharide results in local RAS activation in the adipose tissue of rat offspring.

Autor: Meng Gao, Xingxing Zhang, Xin Chen, Cunyun Mi, Yujie Tang, Jianzhi Zhou, Xiaohui Li

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111376 (2014)

BACKGROUND: Adult metabolic syndrome may originate in part during fetal or early life. This study was designed to investigate the effects of prenatal exposure to lipopolysaccharide (LPS) on adipose development and local renin-angiotensin system (RAS)

Externí odkaz: https://doaj.org/article/9748a4fe1e6b4dee9a188c95a28ae65e

scSTATseq: Diminishing Technical Dropout Enables Core Transcriptome Recovery and Comprehensive Single-cell Trajectory Mapping

Autor: Ying Wan, Xingzhao Wen, Gang Chen, Xiangyu Tang, Xin Qiu, Fa Xu, Qingshan Ni, Hao Xu, Zhou Peng, Zihan Zheng, Haili Yu, Yiwen Zhou, Liyun Zou, Jianzhi Zhou, Haiyang Wu

The advent of single-cell RNA sequencing has provided illuminating information on complex systems. However, large numbers of genes tend to be scarcely detected in common scRNAseq approaches due to technical dropout. Although bioinformatics approaches

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0add9abc9be3ba6ef4279f878a72e70b

TLR2-Deficiency Promotes Prenatal LPS Exposure-Induced Offspring Hyperlipidemia

Autor: Xin Chen, Shuhui Li, Wenjing Lai, Dayan Cao, Jianzhi Zhou, Xiaoyong Huang, Xiaohui Li, Wen-jia Wang

Publikováno v: Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology

Toll-like receptor 2 (TLR2), which recognizes several lipopeptides and transduces inflammatory signaling, promotes the pathogenesis of diet-induced dyslipidemia and obesity. TLR2-deficient mice were shown to have improved insulin sensitivity and redu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf708f0fe0a9cda5620894cd811eba0
https://www.frontiersin.org/article/10.3389/fphys.2019.01102/full

Prenatal Exposure to Lipopolysaccharide Results in Myocardial Fibrosis in Rat Offspring

Autor: Meng Gao, Jianzhi Zhou, Yujie Tang, Xiaohui Li, Xin Chen, Shugang Qin

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 10986-10996 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 5
Pages 10986-10996

The epigenetic plasticity hypothesis indicates that exposure during pregnancy may cause adult-onset disorders, including hypertension, myocardial infarction and heart failure. Moreover, myocardial fibrosis coincides with hypertension, myocardial infa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837a1ab295ce44a94795257c4eb1e20c
https://doi.org/10.3390/ijms160510986