Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jianzhao Peng"'
Publikováno v:
Journal of the American Chemical Society. 145:10998-11004
Autor:
Yuqing Deng, Jianzhao Peng, Feng Xiong, Yinan Song, Yu Zhou, Jianfu Zhang, Fong Sang Lam, Chao Xie, Wenyin Shen, Yiran Huang, Ling Meng, Xiaoyu Li
Publikováno v:
Angewandte Chemie. 132:15075-15082
Publikováno v:
Chemical Communications. 56:6134-6137
Aldehyde is a versatile chemical handle for protein modification. Although many methods have been developed to label proteins with aldehyde, target-specific methods amenable to endogenous proteins are limited. Here, we report a simple affinity probe
Autor:
Chao Xie, Wenyin Shen, Ling Meng, Yiran Huang, Jianzhao Peng, Jianfu Zhang, Fong Sang Lam, Yuqing Deng, Yinan Song, Yu Zhou, Feng Xiong, Xiaoyu Li
Publikováno v:
Angewandte Chemie (International ed. in English). 59(35)
Dynamic combinatorial libraries (DCLs) is a powerful tool for ligand discovery in biomedical research; however, the application of DCLs has been hampered by their low diversity. Recently, the concept of DNA encoding has been employed in DCLs to creat
Publikováno v:
Biochemical and biophysical research communications. 533(2)
DNA-encoded chemical library (DEL) has emerged as a powerful technology for ligand discovery in biomedical research. Recently, we have developed a DNA-encoded dynamic library (DEDL) approach by incorporating the concept of dynamic combinatorial libra
Autor:
Qingrong Li, Xin Li, Xuhui Huang, Liangxu Xie, Xiang David Li, Xiaoyu Li, Chen Li, Yu Zhou, Ling Meng, Jianzhao Peng, Jianfu Zhang
Publikováno v:
Journal of the American Chemical Society. 140:15859-15867
Dynamic combinatorial library (DCL) has emerged as an efficient tool for ligand discovery and become an important discovery modality in biomedical research. However, the applications of DCLs have been significantly hampered by low library diversity a
Publikováno v:
Bioorganic & Medicinal Chemistry. 45:116328
DNA-encoded chemical library (DEL) has emerged to be a powerful ligand screening technology in drug discovery. Recently, we reported a DNA-encoded dynamic library (DEDL) approach that combines the principle of traditional dynamic combinatorial librar
Publikováno v:
Angewandte Chemie (International ed. in English). 59(40)
Histone deacetylase (HDAC) is a major class of deacetylation enzymes. Many HDACs exist in large protein complexes in cells and their functions strongly depend on the complex composition. The identification of HDAC-associated proteins is highly import
Publikováno v:
European Journal of Organic Chemistry. 2016:535-540
Organocatalytic asymmetric domino reactions of γ-nitro ketones and enones have been developed for the construction of functionalized cyclohexane skeletons with four stereogenic carbon atoms, including one tetrasubstituted carbon stereocenter. 5-Nitr
Publikováno v:
Proceedings of the 2016 3rd International Conference on Materials Engineering, Manufacturing Technology and Control.
This paper is aimed at improving the LCA method of carbon emissions on construction. Because when using the LCA method for computing carbon emissions of the construction, low-load operating time and quitting time of construction machinery are calcula