Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Jianyuan, Sun"'
Autor:
Mingming Xing, Yang Li, Yuqi Zhang, Juemou Zhou, Danting Ma, Mengqi Zhang, Minglei Tang, Ting Ouyang, Fumiao Zhang, Xiaofeng Shi, Jianyuan Sun, Zuxin Chen, Weiping J. Zhang, Shuli Zhang, Xiangyang Xie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The paraventricular hypothalamus (PVH) is crucial for food intake control, yet the presynaptic mechanisms underlying PVH neurons remain unclear. Here, we show that RUVBL2 in the PVH is significantly reduced during energy deficit, and knockou
Externí odkaz:
https://doaj.org/article/e355cb264c7f44cd8593ee4bc233abfe
Autor:
Yiwei Gao, Shuai Xu, Xiaoli Cui, Hao Xu, Yunlong Qiu, Yiqing Wei, Yanli Dong, Boling Zhu, Chao Peng, Shiqi Liu, Xuejun Cai Zhang, Jianyuan Sun, Zhuo Huang, Yan Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
The CaV2.3 channel is involved in synaptic plasticity and neurological disorders. Here, authors resolve the human CaV2.3 structure to explore functional heterogeneity of VSDs and elucidated the closed- and open-state inactivation mechanisms of the ch
Externí odkaz:
https://doaj.org/article/31904ce1f2d8423dbb6f6cc958e2934c
Autor:
Xiaojing Li, Feng Xu, Hao Xu, Shuli Zhang, Yiwei Gao, Hongwei Zhang, Yanli Dong, Yanchun Zheng, Bei Yang, Jianyuan Sun, Xuejun Cai Zhang, Yan Zhao, Daohua Jiang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
NaV1.3 is involved in neuronal development, hormone secretion and pain perception. Here, the authors elucidate the molecular mechanism for modulation of NaV1.3 by a site-2 neurotoxin bulleyaconitine A and a subtype selective antagonist ICA121431.
Externí odkaz:
https://doaj.org/article/4638d0c72f164f5d8a96ae7095873380
Autor:
Chen Xiang, Peihua Chen, Qin Zhang, Yinghui Li, Ying Pan, Wenchun Xie, Jianyuan Sun, Zhihua Liu
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102849- (2021)
Summary: The intestinal microbiota closely interacts with the neuroendocrine system and exerts profound effects on host physiology. Here, we report that nucleotide-binding oligomerization domain 1 (Nod1) ligand derived from intestinal bacteria modula
Externí odkaz:
https://doaj.org/article/9d9d158d1a484809b7ef4ff8ded2a59e
Publikováno v:
Journal of Marine Science and Engineering, Vol 10, Iss 10, p 1513 (2022)
To solve the problems of underwater image color deviation, low contrast, and blurred details, an algorithm based on color correction and detail enhancement is proposed. First, the improved nonlocal means denoising algorithm is used to denoise the und
Externí odkaz:
https://doaj.org/article/33a1fe62a54d4714b9531a52faaeb856
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Trimeric intracellular cation (TRIC) channels are crucial for Ca2+ handling in eukaryotes and are involved in K+ uptake in prokaryotes. Recent studies on the representative members of eukaryotic and prokaryotic TRIC channels demon
Externí odkaz:
https://doaj.org/article/09ca12df5b9d4497a89d15572249d3f4
Publikováno v:
IEEE Access, Vol 5, Pp 1398-1408 (2017)
Random Forests are powerful classification and regression tools that are commonly applied in machine learning and image processing. In the majority of random classification forests algorithms, the Gini index and the information gain ratio are commonl
Externí odkaz:
https://doaj.org/article/2ee384a7657f421ea7bd0893dfa13f55
Publikováno v:
Sun, J, Yu, H, Zhong, G, Dong, J, Zhang, S & Yu, H 2020, ' Random shapley forests: cooperative game based random forests with consistency ', IEEE Transactions on Cybernetics . https://doi.org/10.1109/TCYB.2020.2972956
The original random forests algorithm has been widely used and has achieved excellent performance for the classification and regression tasks. However, the research on the theory of random forests lags far behind its applications. In this paper, to n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86639a87913173cc75cde78adb686047
https://doi.org/10.1109/tcyb.2020.2972956
https://doi.org/10.1109/tcyb.2020.2972956
Autor:
Yiwei Gao, Shuai Xu, Xiaoli Cui, Hao Xu, Yunlong Qiu, Yiqing Wei, Yanli Dong, Boling Zhu, Chao Peng, Shiqi Liu, Xuejun Cai Zhang, Jianyuan Sun, Zhuo Huang, Yan Zhao
High-voltage-activated R-type CaV2.3 channel plays pivotal roles in many physiological activities and is implicated in epilepsy, convulsions, and other neurodevelopmental impairments. Here, we determine the high-resolution cryo-electron microscopy (c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740aea160856adb47e27ce756d824fd4
https://doi.org/10.1101/2022.12.19.521133
https://doi.org/10.1101/2022.12.19.521133
Autor:
Yalong Wang, Ying Zhu, Wanru Li, Shuxin Yan, Chao Li, Kunpeng Ma, Meiqin Hu, Cuilian Du, Lei Fu, Jianyuan Sun, Xi Zhang, Claire
Publikováno v:
Journal of Neuroscience; 9/6/2023, Vol. 43 Issue 36, p6230-6248, 19p