Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jianyong Sheng"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Introduction Balloon flower root-derived exosome-like nanoparticles (BDEs) have recently been proposed as physiologically active molecules with no cytotoxicity. However, the therapeutic effects of drug-induced hepatotoxicity of BDEs have not
Externí odkaz:
https://doaj.org/article/42b20f11af1e467ebef1cf1ba908c921
Autor:
Qiujun Qiu, Sunhui Chen, Huining He, Jixiang Chen, Xinyi Ding, Dongdong Wang, Jiangang Yang, Pengcheng Guo, Yang Li, Jisu Kim, Jianyong Sheng, Chao Gao, Bo Yin, Shihao Zheng, Jianxin Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 5091-5106 (2023)
Despite exciting achievements with some malignancies, immunotherapy for hypoimmunogenic cancers, especially glioblastoma (GBM), remains a formidable clinical challenge. Poor immunogenicity and deficient immune infiltrates are two major limitations to
Externí odkaz:
https://doaj.org/article/3527f99918d44dcbb638a2f5613534a2
Autor:
Xiaoyu Yang, Jianyong Sheng, Jitang Chen, Tianhao Peng, Xiquan Yin, Wei Liu, Ming Liang, Jiangling Wan, Xiangliang Yang
Publikováno v:
Journal of Functional Foods, Vol 57, Iss , Pp 309-316 (2019)
The present study aims to investigate the effect of Longan Arillus extract (ELA) on oral absorption of bioactive peptides (cationic P1: VEGNLQVLRPR, anionic P2: HNLDTQTESDV) derived from defatted walnut meal hydrolysates (DWMH). Oral co-delivery of E
Externí odkaz:
https://doaj.org/article/4b3672686b544eaa82fde0b6d70d97e8
Autor:
Linlin Shi, Jianyong Sheng, Guozhong Chen, Changping Shi, Chaiwoo Park, Bixiang Zhang, Xiangliang Yang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Interleukin-2 (IL-2) serves as a pioneer of immunotherapeutic agent in cancer treatment. However, there is a considerable proportion of patients who cannot benefit from this therapy due to the limited clinical responses and dose-limiting t
Externí odkaz:
https://doaj.org/article/0da2f4c252f44dc49cf52bc3cd8ea641
Autor:
Jianyong Sheng, Xiangliang Yang, Jiangling Wan, Xiaoning Ren, Lisi Shi, Yu Li, Wenliang Liu, Ying Wan, Zhiqiang Luo, Xiaofeng Yu
Publikováno v:
Nanoscale. 12:12578-12588
Synergistic therapy with high efficacy and low side effects is of great significance in cancer treatment, and therefore the elaborate design of advanced nanocarriers to benefit diverse loading requirements of size-varied therapy agents is of critical
Autor:
Xiangliang Yang, Xiaoyu Yang, Tianhao Peng, Xiquan Yin, Wei Liu, Jitang Chen, Jiangling Wan, Ming Liang, Jianyong Sheng
Publikováno v:
Journal of Functional Foods, Vol 57, Iss, Pp 309-316 (2019)
The present study aims to investigate the effect of Longan Arillus extract (ELA) on oral absorption of bioactive peptides (cationic P1: VEGNLQVLRPR, anionic P2: HNLDTQTESDV) derived from defatted walnut meal hydrolysates (DWMH). Oral co-delivery of E
Autor:
Xiangliang Yang, Jianyong Sheng, Tianhao Peng, Xiquan Yin, Jiangling Wan, Jitang Chen, Xiaoyu Yang, Wei Liu, Ming Liang
Publikováno v:
Journal of Agricultural and Food Chemistry. 67:3305-3312
The peptide components of defatted walnut ( Juglans regia L.) meal hydrolysate (DWMH) remain unclear, hindering the investigation of biological mechanisms and exploitation of bioactive peptides. The present study aims to identify the peptide composit
Autor:
Jianyong Sheng, Jun Zhu, Mengli Wang, Xiangliang Yang, Linlin Shi, Liu Zhi, Han Luo, Bixiang Zhang
Publikováno v:
Theranostics
Galunisertib (Gal) is a transforming growth factor (TGF-β) blockade which is being investigated as a potential tumor immunotherapy candidate drug in clinical trials. However, primary or acquired resistance is often found in the recruited cancer pati
Autor:
Liu Zhi, Bei Li, Peng Zhu, Bixiang Zhang, Guozhong Chen, Xiangliang Yang, Linlin Shi, Chaiwoo Park, Changping Shi, Jingyi Wang, Jianyong Sheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundInterleukin-2 (IL-2) serves as a pioneer of immunotherapeutic agent in cancer treatment. However, there is a considerable proportion of patients who cannot benefit from this therapy due to the limited clinical responses and dose-limiting to
Autor:
Xiaoyu Yang, Qingyao Liu, Xiangliang Yang, Jiangling Wan, Jianyong Sheng, Ming Liang, Xiaoli Lan, Xiquan Yin, Wei Liu, Han Luo
Publikováno v:
Journal of agricultural and food chemistry. 68(3)
The present study aimed to investigate the combined effects of defatted walnut meal hydrolysate (DWMH) and tea polyphenols (TP) on learning improvement and to explain mechanistically why the combined treatments were more effective than either subject